Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042963 (vomiting)
 31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A study was carried out on 62 male infant children, aged 3-24 months in San Jose, Puerto Rico. The purpose of the study was to discover if a mixture of glucose and amino acids enhances sodium and water absorption, thereby diminishing the volume of oral rehydration solution, stool output and duration of diarrhea. To investigate this hypothesis, the efficacies of two oral rehydration solutions (ORT) were compared: the ORT recommended by WHO (mmol/L) Na + 90, K + 20, C1- 80 Citrate 10, Glucose 110, yielding an osmolality of 310 (mosmol/kg H20) and one containing (mmol/L): Na+ 90, K+ 20, C1-80, Citrate 10, Glucose 67, Glycine 53, Glycylglycine 30, and yielding an osmolality of 350 (mosmol/kg H2)). Results are as follows: the infants were divided into two groups - A and B - with each consisting of 31 males per group; group A received the glycine based solution while group B received the WHO/ORS. There was no significant difference in: the mean age of the patients, mean time and mean number of vomiting, duration of diarrhea, number of stool motions, and duration of fever before admission between the two groups. The glycylglycine/glycine/ glucose electrolyte solution was found to be suitable for rehydration, but is not superior to the standard WHO/ORS. The glycine solution resulted in shortening the duration of diarrheal illness, but failed to decrease the ingested amount of ORS as well as the stool output volume.
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PMID:Comparison of efficacy of a glucose/glycine/glycylglycine electrolyte solution versus the standard WHO/ORS in diarrheic dehydrated children. 319 75