Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042963 (vomiting)
 31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Food poisoning due to "Godofu (Sasayuki tofu)" as a main causative foodstuff which broke out on July 14, 1988. There were 670 out of 918 persons who ingested this food who became ill (incidence 73.0%). The main symptoms were diarrhea (93.4%), fever (77.5%), abdominal pain (64.5%), and vomiting (19.9%). A high degree of fever and watery diarrhea were characteristic of this poisoning. The average latent period was 35 hours with a range of one to 156. The O164:H- strains of enteroinvasive Escherichia coli (EIEC) were detected from 22 of the 32 fecal samples collected from the patients, five of ten samples collected from workers engaged in tofu making, and one sample of left-over Godofu. The virulence of EIEC strains isolated from the patients, workers, and left-over food was confirmed by invasion into HeLa and HEp-2 cells, Sereny test, and ELISA test to detect invasive plasmid-derived protein of the organism (conducted at Tokyo Metropolitan Research Laboratory of Public Health). These EIEC strains were sensitive (less than or equal to 0.19 to 6.25 micrograms/ml) to GM, ABPC, CBPC, CER, CET, NA, PB, MINO, TC and CP as well as KM and OFLX which were used for treatment. However, their susceptibility to FOM varied to some extent (6.25 to 25.0 micrograms/ml) and one strain isolated from a tofu worker was resistant to MINO, TC, FOM and CP (25 to greater than or equal to 100 micrograms/ml). Since investigation revealed that Godofu was left at room temperature about 29 degrees C until ingested, we did a experiment to check the bacterial growth in Godofu under similar conditions at the time of outbreak.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Food poisoning caused by enteroinvasive Escherichia coli (O164:H-)--a case in which the causative agent was identified]. 143 58

We experienced a hospital outbreak of salmonella food poisoning after ingestion of omelet which was the hospital evening meal on August 8, 1999. Total number of patients was sixty-two (Male 25: female 37) and the mean age was 52.1 years old. Salmonella Enteritidis was isolated from the stool in 59 cases. Twenty-one of them were associated with the immunosuppression (12 with malignancy, 6 with DM, one with nephrotic syndrome, one with chronic nephritis and one with allergic purpura). Clinical symptoms of the patients were composed of watery diarrhea (100%), fever (88.7%), abdominal pain (82.3%), nausea (45.2%) and vomiting (25.8%). The laboratory data revealed leukocytosis (15/47 = 31.9%), increased CRP (44/46 = 95.7%), elevated creatinin (1/37 = 2.7%) and hypokalemia (5/42 = 11.9%). MICs of 20 strains isolated in our laboratory almost coincided with each other indicating that the source of bacteria was probably the same. In vitro, S. Enteritidis were sensitive to OFLX, TFLX, FOM, most of PCs, CEPs, AGs but resistant to MPIPC, CAM, CLDM, VCM. Therefore we administered LVFX to 59 cases (alone in 45cases, combination with FOM in 6 cases), NFLX to two children and FMOX to one pregnant woman. Lactobacillus was administered to 28 cases (45.2%) and antidiarrhetics were given to 6 cases (9.7%). Finally all patients improved within two weeks. We suspect that the salmonella food poisoning was due to infected egg. The partially cooked omelet would permit the growth of a sufficient inoculum to cause disease. To prevent food poisoning, we have to be consistent in cooking the food well (at 75 degrees C, for more than 1 minute) and should not have omelets during the hot summer season.
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PMID:[Clinical and bacteriological studies on hospital outbreak of Salmonella enteritidis food poisoning]. 1126 Aug 76

Twenty-four Shigella strains of provisional serovars were isolated from travellers with diarrhea during 1993-2000 at Osaka Airport- and Kansai Airport-Quarantine Station. The outline of these cases were as follows. 1) The provisional serovars of these strains (number of cases) were S. dysenteriae 93-119 (2), S. dysenteriae 204/96 (4), S. dysenteriae I9809-73 (4), S. flexneri 88-893 (9), and S. boydii E16553 (5). 2) Symptoms of these cases were diarrhea, abdominal pain, fever, and vomiting. The ratios of each symptom were 100%, 50%, 50%, and 29.2%, respectively. Typical dysentery symptoms (mucous and bloody stool) were observed in three cases. 3) In six cases (25.0%), plural kinds of entero-pathogenic bacteria were isolated, and in four cases, two kinds of Shigella serovar (known and unknown type) were isolated. 4) The major regions where these travellers were infected was South-west Asia (79.2%). 5) Twenty-three of the Shigella strains (95.8%) of the provisional serovars were resistant to two or more drugs tested (SM, CP, TC, KM, ABPC, NA, and OFLX). The most predominant drug resistance pattern was SM. CP. TC. ABPC.
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PMID:[Isolation of provisional serovars of Shigella in diarrheal cases of tourists]. 1180 36