Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042963 (vomiting)
 31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 50-year-old fisherman was stung in his right hand by a Great Weever fish (Trachinus draco). The crew did not have sufficient medical knowledge to adequately treat him on board. Severe pain, oedema of the hand, fever, vomiting and syncope occurred. Treatment with antibiotics, on board, after disembarkation and later in hospital for six days reduced the severity of the symptoms. However, two years after the accident, the patient still suffered from a dysfunction of the right hand as well as extreme fatigue and intermittent joint complaints. The symptoms mostly commonly arising from a Weever fish sting are: severe pain, local erythema and oedema. Systemic symptoms may sometimes occur: headache, syncope, bradycardia, fever and hypotension. The symptoms of continuous joint pain and severe fatigue following a Weever sting have not been previously described. The Weever fish venom contains a mixture of biogenous amines, of which some are known: 5-hydroxytryptamine, epinephrine, norepinephrine and histamine. The venom's composition has yet to be fully elucidated. In the event of a Weever fish sting, the first aid which should be given is: clean the wound and immerse the affected part of the body for at least 30 minutes in water which is as hot as the victim can tolerate (40-45 degrees C). Persons at risk from Weever fish stings are bathers, especially from the Lesser Weever fish (Echiichthys vipera), and sea fishermen. General practitioners and first aiders in coastal areas as well as sea fishermen should be informed about the first aid to be given in the event of a Weever sting.
 ...
PMID:[Chronic pain and impairment of function after a sting by the great weaver fish (Trachinus draco)]. 1137 1

Stratify care by choosing the optimal medication for a migraine. Severe pain, significant disability, and associated features such as nausea or vomiting necessitate early treatment with specific, high efficacy therapy. Migraine patients may have a spectrum of headache presentations ranging from tension-type headaches to migraine headaches with or without aura. Mild headache types may respond to simple analgesics, though there is evidence that migraineurs will respond to migraine-specific medications such as the triptans for a range of headache phenotypes. Physicians should provide patients with medication to treat nausea and vomiting. They may be infrequent accompaniments, but medication such as a neuroleptic may avoid a trip to the emergency room. Provide rescue medication for an occasional failure of usual treatment to avoid further disability or emergency room visits. Avoid medication overuse by matching treatment to patient needs. A cycle of repetitive and escalating medication use can lead to transformation of migraine into chronic daily headache with analgesic-dependent rebound.
 ...
PMID:Initial Abortive Treatments for Migraine Headache. 1216 22

Severe pain experiences for children at home after tonsillectomy and adenoidectomy (T & A) have been described for more than a decade. Children and their parents are responsible for pain and symptom management during the postoperative home recovery. The purpose of this research was to more fully explore the pain experience and home management practices from the child's perspective. Diaries were used by 34 children (4-18 years of age) to document their pain and other symptoms. A home interview, stories, art work, and personal notes were also explored to fully capture the experience. From the evening of surgery through the second postoperative day, children reported mean pain intensity ratings of 3.1-3.3 out of a possible 4. Pain awakened 64.7% of the children from nighttime sleep and 52.9% reported vomiting associated with nausea. Children received an average of only 50% of the analgesic doses prescribed. Across the 3 postoperative days studied, pain remained severe and interventions offered minimal relief. Neither older children (chi(2) = 1.357, n = 13, df = 2, p = .259) nor younger children (chi(2) = 1.357, n = 12, df = 2, p = .507) reported significant differences in their mean pain intensity across the first 3 postoperative days. Results supported concerns for inadequate home pain management practices in the pediatric T & A population.
 ...
PMID:Pain after tonsillectomy and adenoidectomy: "ouch it did hurt bad". 1803 3