Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound   Target Concepts: Gene/Protein Disease Symptom Drug Enzyme Compound

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Query: UMLS:C0042963 (vomiting)
31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Posterior reversible encephalopathy syndrome (PRES) is characterized clinically by headache, seizures, vomiting, altered mental status, and blurred vision. However, with overlapping and atypical clinical symptoms, PRES becomes a diagnostic challenge. We describe the imaging findings of PRES in magnetic resonance imaging and ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography in an 11-year-old child who presented with features of hypertensive encephalopathy.
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PMID:Posterior Reversible Encephalopathy Syndrome: Pattern on ¹⁸F-Fluorodeoxyglucose Positron Emission Tomography-Computed Tomography Correlated with Magnetic Resonance Imaging in Pediatric Hypertensive Encephalopathy. 3194 77

Posterior circulation acute ischaemic stroke in childhood is a rare but life-threatening disease. We describe a paediatric case of a 17-year-old Indian boy who was admitted to our centre for headache, nausea, vomiting, asthenia, and fever for two days. Computed tomography angiography (CTA), magnetic resonance angiography (MRA) and digital subtraction angiography (DSA) were performed, showing a thrombotic occlusion of the basilar artery due to focal dissection into the proximal third of the left vertebral artery. In a multidisciplinary fashion, we decided to perform a direct aspiration first pass technique (ADAPT), which led to the complete recanalization of either the left vertebral artery or the basilar artery. Twenty-four hours later, despite the anti-edemigenic medical therapy, a preventive occipital craniectomy was performed because of the presence of cerebral oedema to avoid the possible worsening of the patient and compression on the brainstem. Our experience emphasizes the importance of a multidisciplinary and preventive approach in the management of a paediatric posterior fossa ischaemic stroke.
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PMID:A Multidisciplinary Approach in the Management of a Paediatric Posterior Fossa Ischaemic Stroke: A Case Report. 3198 19

Posterior reversible encephalopathy syndrome (PRES) is a neurological disorder which is characterised by variable symptoms, which include visual disturbances, headache, vomiting, seizures and altered consciousness. The exact pathophysiology of PRES has not been completely explained, but hypertension and endothelial injury seem to be almost always present. Vasoconstriction resulting in vasogenic and cytotoxic edema is suspected to be responsible for the clinical symptoms as well as the neuro-radiological presentation. On imaging studies, Symmetrical white matter abnormalities suggestive of edema are seen in the computer tomography (CT) and magnetic resonance imaging (MRI) scans, commonly but not exclusively in the posterior parieto-occipital regions of the cerebral hemispheres. The management is chiefly concerned with stabilization of the patient, adequate and prompt control of blood pressure, prevention of seizures and timely caesarean section in obstetric cases with pre-eclampsia/eclampsia. In conclusion, persistently elevated blood pressures remain the chief culprit for the clinical symptoms as well as the neurological deficits. Early diagnosis by diffusion weighted MRI scans, and differentiation from other causes of altered sensorium i.e. seizures, meningitis and psychosis, is extremely important to initiate treatment and prevent further complications. Although most cases resolve successfully and carry a favorable prognosis, patients with inadequate therapeutic support or delay in treatment may not project a positive outcome.
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PMID:Posterior reversible encephalopathy syndrome (PRES): presentation, diagnosis and treatment. 3246 4


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