Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042963 (vomiting)
 31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Hypertrophic pyloric stenosis (HPS) is a common entity with an incidence of 2-4 per 1000 live births. Current definitive treatment is with pyloromyotomy, which is usually performed laparoscopically. The procedure is generally well tolerated with resolution of the patient's symptoms. In a small percentage of patients, however, there is recurrent vomiting which warrants further investigation. In this pictorial review, the expected post-operative appearance of the pylorus will be described, and the imaging findings and clinical course of two patients with recurrent vomiting after pyloromyotomy will be presented.
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PMID:Imaging findings in infants with recurrent vomiting after pyloromyotomy: a pictorial review. 2632 22

Hypertrophic pyloric stenosis is a common surgical cause of vomiting in infants. Following appropriate fluid resuscitation, the mainstay of treatment is pyloromyotomy. This article reviews the aetiology and pathophysiology of hypertrophic pyloric stenosis, its clinical presentation, the role of imaging, the preoperative and postoperative management, current surgical approaches and non-surgical treatment options. Contemporary postoperative feeding regimens, outcomes and complications are also discussed.
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PMID:Contemporary management of pyloric stenosis. 2752 12

Hypertrophic pyloric stenosis (HPS) is the most common surgically treated disease causing vomiting in infancy, and pyloromyotomy presents around 30% of all operations in this period. Recurrence of the disease is the most serious complication in its treatment. For 16 years period (2000 - 2015) 154 children with HPS were operated n Pediatric Surgery, Plovdiv. Four of them (2.6%), two boys and two girls, were reoperated due to recurrent HPS. Three of the children were sent by other hospital, one of which having Pediatric Surgery, and the other two from regional hospitals. In one case the pyloromyotomy was performed by a general surgeon. The fourth child with recurrent HPS was operated in our clinic. Reoperations were performed between 3rd and 12th day after the first operation (mean 7.5 days). In one case a Heineke mikulicz pyloroplasty was the procedure of choice, and in the other three cases a new pyloromyotomy was made in a different place. Pyloromyotomy for HPS is a routine procedure in pediatric surgery, which has its typical complications and one such is the recurrent HPS. Insufficiently performed pyloromyotomy is among the leading causes for recurrent HPS, therefore, a high level of competence in every surgeon performing it is crucial.
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PMID:[Recurrent hypertrophic pyloric stenosis - diagnostics and treatment]. 2966 82

A male infant aged 45 days presented with projectile nonbilious vomiting for 2 weeks. Ultrasound showed picture of idiopathic hypertrophic pyloric stenosis. Laparoscopic pyloromyotomy was done, but postoperative vomiting that was mainly nonbilious continued without improvement. After 4 days of persistent vomiting, laparoscopic exploration was done and complete pyloromyotomy was confirmed and malrotation with complete Ladd's band was found, then case converted to open laparotomy and Ladd's procedure was done. Postoperatively, vomiting stopped completely and baby began gradual feeding till reaching full feed. Despite that the presentation of concurrent Idiopathic Hypertrophic Pyloric Stenosis with malrotation is extremely rare; a formal laparoscopic abdominal exploration should be done as the first step before proceeding to pyloromyotomy.
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PMID:Idiopathic Hypertrophic Pyloric Stenosis with Complete Ladd's Band: A Rare Association. 3176 28


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