Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042963 (vomiting)
 31,883 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The case reported here was a 6-year-old girl who complained of sudden headache and nausea followed by vomiting and visited our clinic. Physical examination revealed mental confusion, right abducent palsy and papilledema. Computed tomography demonstrated a round high-density area surrounded by a low-density zone indicating cystic nature and including high-density part. The lesion was located in the right parietal lobe attaching to the flax. Right frontoparietal craniotomy disclosed a brain tumor containing a large cyst in which bleeding from the tumor was confirmed. This mass lesion was totally resected out. Histo-pathological diagnosis was meningioma to contained cystic formation and hemorrhage from the tumor. Therefore, further discussion on the pathogenesis of cyst formation and bleeding from this tumor was presented.
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PMID:[Cystic meningioma associated with intratumoral hemorrhage in a child--report of a case and review of the literature]. 712 32

A case of brain tumor complicating a full-term pregnancy is reported. The literature is reviewed to show the effect of pregnancy on these tumors, the method of diagnosis, and management. Pregnancy often unmasks the existence of an intracranial neoplasm. The diagnosis can easily be missed, as the symptoms such as headache, vomiting, visual disturbance etc. are often encountered in pregnancy with or without pre-eclampsia. A high index of suspicion on the part of the obstetrician is a key to timely diagnosis. Computerized axial tomography is extremely useful in confirming or refuting the diagnosis of brain tumor. Generally speaking, neurosurgical intervention is best deferred until after delivery. In most cases, pregnancy may be allowed to continue under close supervision until the baby is reasonably mature. Labor may be induced in suitable cases, and the baby should be delivered by elective forceps as soon as the second stage of labor is reached to cut down maternal bearing-down efforts.
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PMID:Brain tumors and pregnancy. Presentation of a case and a review of the literature. 719 55

A 37-year-old housewife who had episodes of surgical removal for an alveolar soft-part sarcoma of her right leg 15 years ago, and total removal for right lung metastasis 2 years ago, was admitted to our service with complaints of headache, vomiting, dyscalculia and recent memory disturbance which started about 4 months prior to admission. Neurological examination revealed papilledema and disorientation. Left carotid angiography and CT scan showed a ball-like vascular tumor in the left frontal lobe. Presumptive diagnosis of metastatic brain tumor in the left frontal lobe was made in our service. Left fronto-parietal craniotomy was carried out on Feb. 22, 1977 and total removal for the metastatic tumor were made. Specimens of the tumor showed typical feature of alveolar soft-part sarcoma histologically. Postoperative course was well and she was discharged without neurological deficits. Two years after the previous surgery for cerebral metastasis, another metastatic tumor was found in the left frontal lobe again. Total removal for this solitary metastatic tumor was performed again. Histological and electron microscopical examination was made with this tumor specimen. Typical feature of alveolar soft-part sarcoma was confirmed. She was discharged with a marked improvement of her symptoms. At present, it has been passed about a year after the second surgery on her, she is doing well without neurological deficits. Clinical features of alveolar soft-part sarcoma were discussed, especially with the comparison of clinical feature between the reported cases of Japan and the cases of foreign countries. Regarding the choice of the treatment of this tumor, total removal was seemed to be the best management. Therefore, all efforts should be focussed to discover in the earlier stage of this tumor.
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PMID:[A case of alveolar soft-part sarcoma with lung and cerebral metastasis (author's transl)]. 724 44

The activation of oncogenes and the inactivation of tumor suppressor genes within neoplastic cells lead to transformation and loss of growth control. The key clinical feature that should arouse suspicion of a primary brain tumor and lead to a prompt evaluation is the progressive nature of the signs and symptoms, which include headaches, nausea and emesis, double vision, change in personality or cognition, speech difficulty, seizures and weakness. Neuroimaging with contrast-enhanced computed tomography or magnetic resonance imaging is the best method of confirming the presence of a primary brain tumor. Initial treatment in most patients is biopsy or surgical resection. For malignant and selected benign primary brain tumors, further treatment is necessary and may include radiation therapy, chemotherapy or experimental protocols.
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PMID:Primary brain tumors: review of etiology, diagnosis and treatment. 794 21

Neonatal brain tumor is rare, but is so important a disease when considering the pathogenesis of the brain tumor that numerous review articles have been described. Today, the availability of noninvasive imaging procedures such as CT and MRI make it easy to diagnose, and some successful operative cases have been reported. We report three cases of neonatal brain tumors presented clinically within the first 2 weeks. Case 1: A full term boy admitted with projectile vomiting, enlarged head and left peripheral type facial palsy at the age of 12 days. CT scan revealed a large heterogeneous mixed-density mass in the left cerebellar hemisphere. Partially removed surgical specimen consisted of primitive glial cells differentiating with the ependymal cell immunohistochemically and electron microscopically, and diagnosed as ependymoblastoma. He had whole brain irradiation postoperatively, but died from respiratory distress 7 months later without tumor regrowth indicated on CT. Case 2: A full term boy admitted with progressive enlarging of the head at the age of 10 days. CT scan revealed a high-density mass in the cerebellar vermis and an obstructive hydrocephalus. Partially removed surgical specimen, diagnosed as medulloblastoma. He was irradiated throughout the whole brain and spinal cord, but died from intracranial dissemination 5 months later. Case 3: A 32-year-old female multipara was diagnosed as hydramnion during 28 weeks gestation. The concentration of AFP was very high in the amniotic fluid. A premature female fetus, weighing 1,650 g, was delivered by cesarean section for premature separation of the placenta during an estimated 30 weeks gestation.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Neonatal brain tumor, a report of three cases]. 816 55

The authors report a case of 6-month-old boy with cerebellar medulloblastoma associated with malignant rhabdoid tumor of the kidney, presenting with an abdominal mass, large head and projectile vomiting. Following removal of the renal tumor, the mass arising from the superior vermis about 6 cm in diameter was removed by a combined right occipital transtentorial and suboccipital approach. The patient had been well for 3 months after surgery followed by chemotherapy but died eventually of tumor recurrence in the abdomen. Reported cases of malignant rhabdoid tumor of the kidney associated with brain tumor are reviewed and its characteristics are discussed.
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PMID:Medulloblastoma associated with malignant rhabdoid tumor of the kidney: case report. 822 Jul 86

This retrospective chart review was conducted to determine the presenting signs and symptoms of patients with primary brain tumors diagnosed in the emergency department. There were 101 patients (65 males and 36 females) identified with a hospital discharge diagnosis of primary brain tumor who were admitted through the emergency department. The presenting symptoms included headache (56 patients), altered mental status (51 patients), ataxia (41 patients), nausea or vomiting (37 patients), weakness (27 patients), speech deficits (21 patients), and sensory abnormalities (18 patients). The presenting signs included motor weakness (37 patients), ataxia (37 patients), papilledema (28 patients), cranial nerve palsies (26 patients), visual deficits (20 patients), and speech deficits (12 patients). The average age was 42.8 years, with a range of 3 days to 88 years. The majority of tumors were malignant astrocytomas. Tumor location was cortical in 68 patients, subcortical in 9 patients, and brainstem or cerebellum in 24 patients. In conclusion, patients of all ages may present to the emergency department with a variety of symptoms resulting from a primary brain tumor. Headache and altered mental status were common in our series of patients, but symptoms will depend on the size, location, and type of tumor. A complete neurologic examination is essential, including evaluation for papilledema.
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PMID:Signs and symptoms of patients with brain tumors presenting to the emergency department. 834 May 78

We reported a case of a patient who suffered from a cerebrovasculopathy after irradiation therapy for astrocytoma located at the left temporal lobe. An eleven year-old boy who presented himself with headache and vomiting as his chief complaints received partial removal of a tumor. Histological diagnosis of the tumor was astrocytoma (grade II). His preoperative cerebral angiograms showed mass sign solely, without stenosis or occlusion of the cerebral vessel. Postoperatively, he was treated with irradiation therapy involving the whole brain with a total of 30 Gy, and gamma knife therapy. Six months after irradiation, he started suffering from frequent cerebral ischemic attacks, but there was no regrowth of the tumor visible on CT scans. Cerebral angiograms were made again, and revealed multifocal stenoses in the bilateral internal carotid arteries, middle cerebral arteries, and the anterior cerebral artery. His symptoms did not improve after conservative treatment with steroids, calcium antagonist, or low molecular weight dextran. Although he received a superficial temporal artery-middle cerebral artery (STA-MCA) anastomoses bilaterally, multiple cerebral infarctions appeared. Although irradiation therapy is acceptable in patients with brain tumor, a cerebrovasculopathy after irradiation should be considered as one of the most important complications, and the risk incurred by irradiation therapy should lead to more careful consideration and caution when treating intracranial brain tumors, especially in children. From our experience, the usefulness of bypass surgery for radiation-induced cerebrovasculopathy is still controversial.
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PMID:[Radiation-induced cerebrovasculopathy: a case report and review of the literature]. 836 76

In Part I of this article, we present our data collected over the past 8 years on the clinical evaluations of pediatric brain tumors with an emphasis placed on the more common neoplasms. Our data consists of 385 children ranging in age from newborn to 18 years. The majority of children presented with signs of raised intracranial pressure (including nausea, vomiting, and headaches), seizures or other focal neurologic deficits. Five percent of our children presented to outlying hospitals with symptoms that retrospectively turned out to be due to brain neoplasms but were misdiagnosed as "gastroenteritis," "viral upper respiratory tract infection," or even viral meningitis. These delays in diagnosis can cause serious negative outcomes for these patients and can be avoided through more careful neurologic and ophthalmologic examination at the time of first presentation. Central nervous system neoplasms are not uncommon in children and any child presenting with nausea, vomiting, and headaches should raise the suspicion of a primary brain tumor and should receive both a thorough neurologic exam and screening for papilledema. If papilledema is present, these children should be referred for proper neuroradiologic evaluation (which will be addressed in Part II.
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PMID:The clinical and radiological evaluation of primary brain tumors in children, Part I: Clinical evaluation. 836 34

The incidence of sudden death due to undiagnosed primary intracranial tumor is low in forensic autopsy. The cause of death in a 20-year-old male found dead in his dormitory room was glioblastoma multiforme in the left temporal lobe. The direct cause of death was hemorrhage in the tumor. Three nights before the discovery of his body, he had several episodes of vomiting and had been absent from work since that time. On discovery of the body, it was thought that he had been dead for about 2 days. About 4 months before his death, he consulted an eye doctor for "fatigue of the eyes" and 1 month thereafter he visited the neurosurgical department of a hospital complaining headache. A diagnosis of tension headache was made; the possibility of brain tumor appears not to have been considered. A causal relationship between head trauma and hemorrhage in the tumor was excluded based on the circumstantial evidence.
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PMID:A case of sudden death by undiagnosed glioblastoma multiforme. 839 9


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