Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042961 (volvulus)
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Human Gene/Protein
64kDa) 11.6
hr44 11.3
mitochondrial solute carrier protein 10.5
ankyrin-related 9.9
64kD 9.9
glutathione S-transferase 2 9.7
Wol 9.7
Spermidine acetyltransferase 9.7
Leukocyte antigen 9.7
ALMS 9.2
AZI 8.5
RAL 8.4
ARID4A 8.3
allele b 8.3
IA-6 8.3
GST2 8.2
cathepsin Z 8.2
ATPase subunit 8 8.2
OC3 8.0
GST-1 7.8
PRKCZ 7.7
Glutamate-cysteine ligase 7.7
GlcNAc6ST-2 7.7
PEBP1 7.6
LADD 7.6
Hensin 7.6
GST1 7.5
PSS1 7.5
Nip3 7.4
HSP-60 7.3
EDN 7.1
NADH dehydrogenase subunit 4 6.9
proline isomerase 6.8
ASP 6.7
GlcNAc6ST-1 6.7
DQB1*0603 6.6
NALCN 6.5
eosinophil-derived neurotoxin 6.5
OV-1 6.5
CDH17 6.4
asparaginyl-tRNA synthetase 6.4
C.elegans 6.4
tropomyosin isoform 6.4
TARP 6.4
calumenin 6.3
ALMS1 6.3
C1qR 6.3
thioredoxin-like protein 6.3
SL1 6.2
CCL15 6.2
CCL23 6.1
CPL 6.1
ABC-transporter 6.0
beta-galactoside-binding lectin 6.0
MCP-4 6.0
SLC26A3 6.0
calgranulin C 6.0
NADP-dependent malic enzyme 6.0
dolichol kinase 5.9
LRP2 5.9
collagen-like protein 5.9
Phosphoglycerate mutase 5.9
SS-A 5.8
Eosinophil peroxidase 5.8
34 kD 5.8
thioredoxin peroxidase 5.8
SMC1A 5.8
KvLQT1 5.7
sorcin 5.7
Sara 5.7
sperm protein 5.7
TC4 5.7
TPN 5.6
macrophage-derived chemokine 5.6
eotaxin-2 5.6
CPZ 5.6
440 kDa 5.6
GK1 5.5
CISS 5.5
Cardiac troponin I 5.5
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Disease
Colonic volvulus 12.9
Diverticulosis of the jejunum 12.9
Intestinal hernia 12.9
Duodenal volvulus 12.9
volvulus 12.9
Mesenteroaxial gastric volvulus 12.9
Other filariases 12.9
Acute gastric volvulus 12.7
Chronic gastric volvulus 12.6
Leopard skin 12.3
Gastric dilatation 11.9
Acquired megacolon 11.9
Cutaneous onchocerciasis 11.9
Mansonella ozzardi infection 11.9
Lane's disease 11.9
Basal pneumonia 11.9
river blindness 11.7
Onchocerciasis 11.5
Splenic flexure 11.4
onchocerciasis 11.4
dipetalonemiasis 11.3
Ectopic ovary 11.3
vaginalitis 11.3
Recurrent intestinal obstruction 11.3
Congenital duodenal stenosis 11.3
Sowda 11.1
mansonelliasis 11.0
Transverse colon 10.9
Transverse colon 10.9
Mal seco 10.9
Mazzotti reaction 10.8
Neonatal intussusception 10.5
megasigmoid 10.5
facio-oculo-acoustico-renal syndrome 10.5
Mansonella perstans infection 10.3
splenoptosis 10.3
Sigmoid colon 10.2
Sigmoid colon 10.2
paraesophageal hernia 10.1
loiasis 10.1
Intestinal necrosis 10.0
argentaffinoma 10.0
Thygeson's superficial punctate keratitis 10.0
Meconium ileus 9.9
hydropneumopericardium 9.9
Ascending colon 9.9
Ascending colon 9.9
Diffuse unilateral subacute neuroretinitis 9.9
Pelvic abscess 9.9
Gastric necrosis 9.8
dolichocolon 9.7
Ileocolic intussusception 9.7
Taenia saginata infection 9.7
Wandering spleen 9.7
sclerokeratitis 9.6
visceroptosis 9.5
Acute hydrops 9.5
Brown bowel syndrome 9.4
pig-bel 9.3
Meckel's diverticulitis 9.2
Wuchereria 9.2
Meconium peritonitis 9.1
Ocular toxocariasis 9.1
chalasia 9.0
Colonic pseudo-obstruction 9.0
Duodenal obstruction 9.0
Small bowel obstruction 9.0
Meconium ileus equivalent 8.9
strangulated hernia 8.9
Colonic obstruction 8.9
obstipation 8.8
bowel obstruction 8.8
Afferent loop syndrome 8.7
Total colonic aganglionosis 8.7
aerophagia 8.6
Meckel's diverticulum 8.6
Stromal keratitis 8.6
AKE 8.6
Meckel's diverticulum 8.6
Diaphragmatic eventration 8.5
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Symptom
Fecal discharge 12.9
Central abdominal pain 12.9
Bilious vomiting 11.5
Rovsing's sign 10.9
Pain worsened 9.7
Persistent vomiting 9.2
abdominal rigidity 8.9
retching 8.6
dysorexia 8.5
Cullen's sign 8.5
Portal venous gas 8.3
McBurney's point 8.0
left lower quadrant pain 7.9
acute abdomen 7.9
generalized abdominal pain 7.8
acute abdominal pain 7.8
chronic constipation 7.3
colic 7.0
Infantile colic 7.0
Murphy's sign 6.9
Skin symptoms 6.7
epigastric pain 6.6
abdominal pain 6.5
right upper quadrant pain 6.4
vomiting 6.3
chyluria 6.2
hyperemesis 6.2
right lower quadrant pain 6.2
constipation 6.1
bloating 6.0
abdominal fullness 5.8
belching 5.7
Wind 5.7
abdominal discomfort 5.6
iliac fossa pain 5.6
Physical findings 5.5
scaly skin 5.4
precordial pain 5.4
Gastrointestinal symptoms 5.3
dyschezia 5.1
intestinal bleeding 4.8
hypoproteinemia 4.7
lethargy 4.4
tense 4.4
prostration 4.3
nausea 4.3
eye pain 4.3
renal colic 4.2
nausea and vomiting 4.1
heartburn 4.1
Respiratory symptoms 4.0
tenesmus 4.0
stomach pain 3.9
emaciation 3.8
anorexia 3.8
abdominal cramps 3.8
pallor 3.6
regurgitation 3.5
tachypnea 3.5
chest tightness 3.3
consciousness disturbance 3.2
respiratory distress 3.1
oliguria 3.0
diarrhea 3.0
shortness of breath 2.8
catatonia 2.7
decreased appetite 2.7
splenomegaly 2.6
tonic-clonic seizure 2.5
acute pain 2.5
chest pain 2.4
physical appearance 2.3
torticollis 2.2
enuresis 2.2
spasm 2.0
cyanosis 2.0
sneezing 2.0
chills 1.8
flank pain 1.8
hepatosplenomegaly 1.7
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Drug
Mectizan 10.7
RAL 8.6
Hetrazan 8.3
Gastrozepin 7.6
Oxfendazole 6.9
Moxidectin 6.9
Prulifloxacin 6.8
Flunixin meglumine 6.6
Syntocinon 6.3
CPZ 5.6
Meconium 5.5
Pentostam 5.5
Hypaque 5.4
Sumatran 4.6
Auranofin 4.5
Doxycycline 4.3
all-trans-retinol 4.2
Olive oil 4.2
Maltose 4.0
Dakar 3.8
Vicryl 3.8
Indocyanine green 3.7
Tuberculin 3.7
Meropenem 3.7
Metrizamide 3.6
Meropenem 3.5
Rutin 3.5
NAG 3.4
Secretin 3.3
AGG 3.2
Gastro 3.0
AMC 2.6
TAT 2.6
Aloe 2.6
Azithromycin 2.6
Fraction 2.5
Pronase 2.5
Glutathione 2.5
IL-2 2.4
Portal 2.4
Vitamin A 2.3
IFN-gamma 2.3
balanced salt solution 2.3
Acacia 2.2
CPR 2.1
Frontal 1.8
CDP 1.7
Ringer's solution 1.4
IFN-beta 1.3
Gel 1.0
Glucagon 1.0
Spectrum 0.9
lactose 0.8
ABC 0.7
Posture 0.5
NADH 0.4
CSF 0.3
nitroglycerin -0.3
vitamin E -1.2
lysine -2.0
Dermatol -2.1
Cardiovasc -3.2
Enzyme
dolichol kinase 6.9
cathepsin X 6.6
asparaginyl-tRNA synthetase 6.4
CPL 5.8
EC 1.1.1.40 5.2
arylamine N-acetyltransferase 5.1
S-adenosylmethionine decarboxylase 5.1
polyamine oxidase 5.0
astacin 4.9
HtrA 4.8
trehalase 4.6
chitinase 4.5
trypanothione reductase 4.4
legumain 4.3
arginine kinase 4.1
venom phosphodiesterase 4.0
PGM 4.0
TGT 3.8
arginine decarboxylase 3.8
prenyltransferase 3.7
CDH 3.7
collagenase 3.7
prenyltransferase 3.6
prenyltransferase 3.6
arginine decarboxylase 3.6
cathepsin L 3.5
peroxiredoxin 3.5
arylalkylamine N-acetyltransferase 3.5
chymase 3.5
gamma-glutamylcysteine synthetase 3.4
FAST 3.3
N-acetyltransferase 3.2
MDH 3.2
PAT 3.1
MDH 3.1
tryptase 3.0
glutathione S-transferase 2.8
proprotein convertase 2.8
TAT 2.6
TSA 2.6
enolase 2.6
acid phosphatase 2.5
phosphoglucomutase 2.4
proteinase K 2.4
P-glycoprotein 2.3
malate dehydrogenase 2.3
apyrase 2.3
xanthine oxidase 2.1
aldolase 2.1
cathepsin G 2.0
prolyl hydroxylase 2.0
prostaglandin synthetase 2.0
glyceraldehyde-3-phosphate dehydrogenase 2.0
cathepsin B 1.8
ornithine decarboxylase 1.8
NADH dehydrogenase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
papain 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.8
elastase 1.7
glyceraldehyde-3-phosphate dehydrogenase 1.7
MIP 1.6
thioredoxin reductase 1.6
diamine oxidase 1.6
PKG 1.6
thromboplastin 1.5
diaphorase 1.4
firefly luciferase 1.4
pepsin 1.4
diaphorase 1.3
5'-nucleotidase 1.2
furin 1.2
hexosaminidase 1.1
tissue plasminogen activator 1.0
phosphofructokinase 0.9
NADPH-diaphorase 0.9
cathepsin D 0.8
trypsin 0.8
aspartate aminotransferase 0.8
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Compound
Ivermectin 9.2
Diethylcarbamazine 9.2
Closantel 8.8
Naganol 8.3
Flubendazole 7.6
Diethylcarbamazine citrate 7.6
Hydroxylysine 7.1
undecanoic acid 7.0
undecanoic acid 7.0
undecanoic acid 7.0
DEC 6.6
barium 6.2
CPL 6.1
Berenil 6.1
Ethyl pyruvate 6.0
Geigy 6.0
N-F 5.9
Suramin 5.6
Mebendazole 5.6
L-Lactate 5.6
2-phosphoglycerate 5.6
Albendazole 5.5
Nifurtimox 5.5
Glyoxal 5.4
CPZ 5.3
Hypaque 5.3
Benin 5.3
Clofazimine 5.2
MGBG 4.9
MGBG 4.9
DEP 4.9
Antimycin 4.9
Pentamidine 4.9
Ecdysone 4.9
Levamisole 4.8
Akron 4.6
Betamethasone 4.5
glutaryl-CoA 4.4
Quinolinic acid 4.4
Doxycycline 4.4
Thiazide 4.2
Parenteral 4.2
TGT 4.1
IDU 4.1
Iodo 4.1
SVC 4.0
Maltose 4.0
Cortisone 4.0
AME 3.8
Alum 3.8
ECP 3.8
Sudan I 3.8
ECP 3.8
ECP 3.8
Quinacrine 3.8
Midazolam 3.6
N-acetyl-D-glucosamine 3.6
Deoxyribonucleic acid 3.6
XTT 3.6
STP 3.5
CDH 3.5
Methylglyoxal 3.5
DOS 3.5
Streptomycin 3.4
TTA 3.4
Chlorpromazine 3.4
PPD 3.4
DIM 3.3
A 42 3.3
Inulin 3.3
PPD 3.3
Secretin 3.3
PAT 3.2
Guo 3.2
PAG 3.2
Rutin 3.0
Azithromycin 3.0
Chloroquine 3.0
Chloroquine 3.0
Neurotensin 2.9
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