Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042961 (volvulus)
 4,305 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Very little of the original primary forest remains in Sierra Leone and the savanna is mainly woodland or a forest-savanna mosaic. The prevalence of microfilariae of Onchocerca volvulus, nodules and moderate or severe skin lesions was higher in forest than savanna villages. In forest villages the prevalence of microfilariae was 71.8% at the iliac crest, 36.6% (outer canthus), 12.8% (cornea) and 34.1% in the anterior chamber of the eye. Corresponding figures for the savanna villages were 51.9%, 20.5%, 5.6% and 21.8%. The overall prevalence of nodules in the forest and savanna was 70.5% and 53.2% respectively, while the prevalence of head and upper body nodules was 14.8% (forest) and 11.0% (savanna). The prevalence of moderate or severe skin lesions was 17.7% in forest and 13.0% in savanna villages. Lesions of the groin and scrotum were few in both zones. In persons aged 30 years or more the prevalence rates of severe eye lesions--sclerosing keratitis, iritis, optic atrophy and choroidoretinitis--were 4.3%, 16.1%, 13.9% and 14.8% respectively in forest villages. Corresponding figures for the savanna villages were 3.7%, 8.7%, 14.2% and 11.3%. Males were more commonly affected than females. At least one of these lesions was found in 32% persons in forest and 24% in savanna villages.
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PMID:Onchocerciasis in Sierra Leone.2: A comparison of forest and savanna villages. 325 13

A study was carried out in selected parts of the Niger Delta Basin on human filariasis and its relationship to clinical signs. One hundred and seventy-six (13.0%) of 1351 individuals examined were infected with microfilaria. Forty-six percent of microfilaria positive cases had M. perstans; 25.6% had W. bancrofti, 19.3% had L. loa, and 9.0% had O. volvulus. The prevalence of filariasis increased with age. Microfilarial density was generally low, 28.4% of infected individuals had counts of 50-100 microfilaria per 20 mm3 blood, 12.5% had counts less than five microfilaria per 20 mm3 blood. Onchocerca microfilariae did not exceed five microfilaria per snip. Microfilarial density was high among individuals aged between 20 and 49 years, but declined with increasing age above 50 years. Acute clinical signs of febrile attack, sink eruptions, and chronic clinical signs of chyluria, hydrocoele, elephantiasis and ocular lesions were observed in 61.9% of infected individuals, 73.4% of clinical cases were febrile attack and skin eruptions, 5.5% were chyluria, 12.8% were elephantiasis of the leg and scrotum, 7.3% were hydrocoele and 0.9% were ocular lesions. Chronic clinical signs were more prevalent in individuals over 40 years of age.
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PMID:The status of human filariasis in relation to clinical signs in endemic areas of the Niger Delta. 353 45

A case of idiopathic or Fournier's gangrene of the scrotum is described with unusual extension to the perineum. The clinical features of this disease are summarized. The literature is reviewed for extra genital extension of this gangrene of unknown aetiology. Coincidental association between infections with Onchocerca volvulus and scrotal gangrene was observed.
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PMID:A case of idiopathic scrotal gangrene (Fournier) with perineal extension. 666 Sep 68

We have experienced a case of shunt tube perforation into the transverse colon in which a Pudenz infantile V-A shunt tube was installed for a hydrocephalic baby. The shunt operation was performed at a year and one month of his age in this patient and bowel perforation was disclosed and corrected twenty months following the operation. From a retrospective point of view, however, slight sign of meningitis could be suspected two months earlier and judging from his symptoms of transient intracranial hypertension, the bowel perforation might be traced back even earlier. In the past twenty year history of V-P shunt maneuver, quite a number of papers on various kinds of specific complications have been reported. On reviewing these reported cases out of English and Japanese literature, numerous abdominal complications such as twenty-eight perforations, fifty CSF ascites or pseudocysts, three umbilical perforations, two vaginal perforations, five migrations into scrotum, and some volvulus and bladder perforations can be collected. These are summarized and discussed briefly in this paper.
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PMID:[Abdominal complications of V-P or L-P shunt operation --a bowel perforation and historical review (author's transl)]. 723 31

In a cross-sectional epidemiological and clinical study of human filariasis, 630 individuals were examined for Onchocerca volvulus, Wuchereria bancrofti and Mansonella perstans infections in five communities in the Kaiyamba Chiefdom, Moyamba District, Sierra Leone. The overall prevalence of O. volvulus infection in males 144(39.1%) and females 94(35.9%) was not significantly different and the sex prevalence rate between communities was also not significant (G = 3, d.f. = 4, P > 0.05). Prevalence of O. volvulus was significantly lower (G = 42.331, d.f. = 5, P < 0.001) in the 5-9 age group (13.3%) compared to the 40-49 age group (61.9%). Sixty-four (10.2%) and 38(6.0%) of individuals examined were positive for W. bancrofti and M. perstans infections respectively and prevalence of both infections in the five communities was not significant. Mixed infections with the all three filaria parasites were recorded in 10(3.2%) of the individuals. One hundred and sixty-four (71.3%) clinical cases due to W. bancrofti were inflammatory in nature; 36.5% were chronic, of which, 26.6% were hydroceles and 9.4% involved elephantiasis of both the scrotum and the lower legs. All 19(3.0%) of M. perstans-related clinical cases were inflammatory. Ninety-three(63.3%) of O. volvulus positive individuals that presented symptoms were inflammatory in nature, 14(9.5%) had ocular symptoms and 57(38.8%) had subcutaneous nodules. These data indicate that infections due to O. volvulus, W. bancrofti and M. perstans may be of public health importance in Sierra Leone.
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PMID:Filariasis in the Kaiyamba Chiefdom, Moyamba District Sierra Leone: an epidemiological and clinical study. 866 63

Meconium periorchitis is uncommon. In the unborn child the peritoneum vaginal canal is open and, secondary to intestinal perforation due to any cause (intestinal atresia, volvulus, and others), meconium peritonitis occurs. The intestinal content reaches the scrotal vaginal cavity. Meconium peritonitis can heal spontaneously and without consequences. Calcified remnants of this event may remain in the peritoneal cavity and/or scrotum. In the newborn, a hydrocele and scrotal mass can be observed; the ultrasound will show a heterogeneous image with calcifications. Meconium periorchitis or meconium vaginalitis resolves spontaneously. The lack of awareness of this disease could lead to unnecessary surgery in the newborn. We present a 33 days old patient with a scrotal mass in whom surgery was performed with the pathological diagnosis of meconium periorchitis.
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PMID:[Meconium periorchitis: A case report]. 2659 10