Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042875 (vitamin E deficiency)
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Human Gene/Protein
ATLD 12.8
alpha-tocopherol transfer protein 12.7
IOSCA 12.1
ATTP 11.9
SANDO 11.8
Caytaxin 11.5
POLG protein 11.5
OSBP2 11.3
SACS 10.5
Type I iodothyronine deiodinase 10.3
SPTBN2 10.2
SRR 9.8
senataxin 9.8
TTP 9.8
DYT11 9.7
RRR 9.6
cellular retinaldehyde-binding protein 9.5
frataxin 9.5
DARS2 9.4
3-beta-hydroxysteroid dehydrogenase 9.2
CRALBP 9.2
ALS4 9.2
FRDA 9.1
RLF 8.9
Fibrillarin 8.9
PLTP 8.9
LDLC 8.8
epsilon-sarcoglycan 8.7
NARP 8.6
vigilin 8.6
collapsin response mediator protein 8.5
SGCE 8.5
SYNE1 8.5
CRMP2 8.5
LIG 8.5
Kell blood group 8.4
Frataxin 8.4
SPG7 8.3
HEMO 8.3
calcium-independent phospholipase A2 8.3
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Disease
Dietetic microangiopathy 15.1
vitamin E deficiency 15.1
Steatitis 14.1
Brown bowel syndrome 13.9
Nutritional muscular dystrophy 13.5
Exudative diathesis 13.5
ATLD 13.1
Detergent sensitivity 13.1
SCAE 13.1
Spastic ataxia 12.8
tocopherol deficiency 12.6
DYT15 12.5
Early Onset Cerebellar Ataxia 12.5
Pseudo-Bartter syndrome 12.3
Pansteatitis 12.3
IOSCA 12.3
VED 12.2
SANDO 11.8
Mitochondrial neurogastrointestinal encephalopathy 11.5
chylomicron retention disease 11.4
MILS 11.0
Selenium deficiency 11.0
Neuroaxonal dystrophy 10.5
Zieve's syndrome 10.3
Spinocerebellar degeneration 10.3
AOA2 10.2
hypobetalipoproteinemia 10.0
white muscle disease 10.0
Distemper 10.0
calorie deficiency 9.9
DYT11 9.8
Friedreich's ataxia 9.8
Thiamine-responsive megaloblastic anemia 9.8
FRDA 9.7
Cholestatic liver disease 9.6
hepatosis 9.6
encephalomalacia 9.6
TTP 9.6
lipoproteinemia 9.5
avitaminosis 9.5
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Symptom
ataxia 8.3
cerebellar ataxia 7.8
Physical findings 6.7
dysarthria 6.5
hypoproteinemia 6.5
emaciation 6.0
hyperoxia 5.9
ophthalmoplegia 5.7
dysesthesia 5.2
abnormal gait 4.9
dystonia 4.6
incoordination 4.3
weakness 4.3
paresis 4.2
chorea 4.0
myoclonus 4.0
spasticity 4.0
hepatosplenomegaly 4.0
tremor 3.9
bradykinesia 3.9
splenomegaly 3.8
acute abdomen 3.5
exertional dyspnea 3.4
diarrhea 3.1
anorexia 2.9
paresthesia 2.8
lethargy 2.6
hepatomegaly 2.6
hypotonia 2.6
respiratory distress 2.4
hypercapnia 2.1
hypothermia 2.0
syncope 1.9
dizziness 1.8
constipation 1.8
nausea 1.6
overweight 1.4
functional recovery 1.4
exhaustion 1.3
collapse 1.3
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Drug
Anoxomer 15.1
Vitamin-E 10.8
Vitamin E 10.6
vitamin E 10.4
Pentane 10.1
Tocopherol 9.3
Liposyn 8.3
Idebenone 8.2
RbCl 7.0
RbCl 7.0
Vitamin A 6.7
SBT 6.5
Singular 6.1
linolenate 5.9
ascorbate 5.5
Riboflavin 5.5
Photofrin 5.2
niacin 5.2
Serum albumin 4.8
Vitamin B12 4.8
Vitamin B 4.8
Scopolamine 4.7
Lovastatin 4.7
Glutathione 4.7
NaI 4.3
NaI 4.3
NaI 4.3
NaI 4.3
ALA 3.6
NADH 3.5
Retinoic acid 3.4
EPA 3.3
Adriamycin 2.9
Bifidobacterium 2.6
Spectrum 2.1
nitroglycerin 2.0
lysine 1.8
Nephron 1.5
Gel 1.2
MAP 1.1
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Enzyme
SRR 10.0
Delta6-desaturase 9.1
D-amino-acid oxidase 7.9
phospholipid hydroperoxide glutathione peroxidase 7.6
NAO 7.6
biotinidase 7.5
Lod 7.5
glutamic dehydrogenase 7.3
propionyl-CoA carboxylase 6.7
propionyl-CoA carboxylase 6.7
ficin 6.6
cathepsin H 6.6
beta-hydroxybutyrate dehydrogenase 6.5
methylmalonyl-CoA mutase 6.4
phospholipase A1 6.4
carnitine acetyltransferase 6.4
glutathione peroxidase 6.2
acyl-CoA oxidase 6.2
TGT 6.1
pyruvate kinase 6.1
NADH-cytochrome b5 reductase 6.0
cytochrome P-450scc 5.9
15-lipoxygenase 5.9
prostaglandin synthetase 5.8
15-hydroxyprostaglandin dehydrogenase 5.8
neutral sphingomyelinase 5.7
acyl-CoA dehydrogenase 5.5
GABA transaminase 5.4
12-lipoxygenase 5.3
glutathione reductase 5.3
succinic dehydrogenase 5.3
LasR 5.3
cholesterol esterase 5.2
CYP7A1 5.1
PTPase 5.1
DOPA decarboxylase 5.1
creatine kinase 5.0
pyruvate dehydrogenase 4.9
pyruvate dehydrogenase 4.9
lecithin:cholesterol acyltransferase 4.9
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Compound
Nodakenin 12.5
Vitamin E 10.5
Nitro blue tetrazolium 10.2
DPPD 10.1
Centrophenoxine 10.0
alpha-CEHC 10.0
alpha-Tocopherol 9.9
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
Centrophenoxine 9.2
Ethoxyquin 9.1
TTP 8.6
beta-tocopherol 8.6
4-Hydroxynonenal 8.1
Thromboxane B2 8.0
Tocopherols 8.0
8-hydroxyguanosine 7.4
Probucol 7.4
Potassium chloride 7.3
selenium 7.1
Methoxamine 7.1
Acridine Orange 7.1
Acridine Orange 7.1
Acridine Orange 7.1
Leupeptin 7.0
Menaquinone 6.9
Nitrofurantoin 6.9
Fluvastatin 6.7
BHA 6.7
Vitamin A 6.7
coenzyme Q10 6.7
Leupeptin 6.6
1,1,1-trichloroethane 6.6
Pyridoxine 6.5
Malondialdehyde 6.5
Triton WR-1339 6.5
12-hydroxyeicosatetraenoic acid 6.4
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