Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042875 (vitamin E deficiency)
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Human Gene/Protein
ATLD 12.8
alpha-tocopherol transfer protein 12.7
IOSCA 12.1
ATTP 11.9
SANDO 11.8
POLG protein 11.5
Caytaxin 11.5
OSBP2 11.3
SACS 10.5
Type I iodothyronine deiodinase 10.3
SPTBN2 10.2
SRR 9.8
senataxin 9.8
TTP 9.8
DYT11 9.7
RRR 9.6
cellular retinaldehyde-binding protein 9.5
frataxin 9.5
DARS2 9.4
3-beta-hydroxysteroid dehydrogenase 9.2
CRALBP 9.2
ALS4 9.2
FRDA 9.1
RLF 8.9
Fibrillarin 8.9
PLTP 8.9
LDLC 8.8
epsilon-sarcoglycan 8.7
vigilin 8.6
NARP 8.6
collapsin response mediator protein 8.5
SGCE 8.5
SYNE1 8.5
CRMP2 8.5
LIG 8.5
Kell blood group 8.4
Frataxin 8.4
SPG7 8.3
HEMO 8.3
calcium-independent phospholipase A2 8.3
EA1 8.2
aprataxin 8.2
holocarboxylase synthetase 8.1
D-amino-acid oxidase 8.0
axon guidance molecule 8.0
DC-STAMP 8.0
cubilin 8.0
McLeod syndrome 7.9
oxysterol-binding protein 7.8
Glutathione peroxidase 7.8
nuclear envelope protein 7.7
sterol regulatory element binding protein-1 7.7
erythrocyte glutathione peroxidase 7.7
Thymidine kinase 7.7
phospholipid hydroperoxide glutathione peroxidase 7.7
biotinidase 7.5
Megalin 7.4
PGDH 7.4
MERRF 7.4
NOVA 7.4
CVID 7.4
IGFBP7 7.3
AHS 7.3
FADH2 7.3
glutamic dehydrogenase 7.3
tenascin-R 7.3
EDD 7.2
SMG 7.2
cysteine proteinase inhibitor 7.1
GAA 7.1
cellular retinoic acid-binding protein 6.9
complement component 3 6.9
propionyl-CoA carboxylase 6.8
thyroxine-binding prealbumin 6.8
glutathione peroxidase 1 6.7
Hsp25 6.6
15-hydroxyprostaglandin dehydrogenase 6.6
alpha-tropomyosin 6.6
GPX2 6.6
SCA1 6.6
phospholipid transfer protein 6.5
APOB 6.5
MSS 6.5
NPQ 6.5
CACNA1A 6.5
cathepsin H 6.5
SCAR 6.4
AOA 6.4
TGT 6.4
carnitine acetyltransferase 6.3
TIS) 6.3
SCA3 6.3
GPX1 6.3
Apolipoprotein B 6.3
megalin 6.3
P100 6.3
jerky 6.2
SC35 6.1
glutathione peroxidase 6.1
DYT1 6.1
lysosomal acid lipase 6.1
pyruvate kinase 6.1
swan 6.0
mitochondrial carrier 6.0
glutathione peroxidase 4 6.0
phosphotyrosine phosphatase 6.0
15-lipoxygenase 5.9
ATP-binding cassette transporter A1 5.9
selenoprotein P 5.9
HSP72 5.9
Trio 5.9
TSK 5.9
neutral sphingomyelinase 5.9
methylmalonyl-CoA mutase 5.9
EDL 5.8
CPI 5.8
MELAS 5.8
vasodilator-stimulated phosphoprotein 5.8
B-12 5.7
pleiotrophin 5.6
transcobalamin II 5.6
4EBP1 5.6
CD166 5.6
TPN 5.5
Glial fibrillary acidic protein 5.5
acyl-CoA dehydrogenase 5.5
apolipoprotein A1 5.5
PDC 5.5
ATA 5.5
GABA transaminase 5.5
12-lipoxygenase 5.4
cytosolic phospholipase A2 5.4
glutathione transferase 5.4
ACD 5.4
microphthalmia-associated transcription factor 5.4
glutathione reductase 5.3
CPK 5.3
B protein 5.3
LCAT 5.3
RER 5.3
gamma-glutamylcysteine synthetase 5.2
CDA 5.2
LPO 5.2
Phospholipase A2 5.2
ATF 5.2
B12 5.2
TM1 5.2
Hepcidin 5.1
Creatine kinase 5.1
CYP7A1 5.0
Prx 5.0
apolipoprotein B 5.0
aryl hydrocarbon hydroxylase 4.9
CCL4 4.9
SDH 4.9
selenoprotein 4.9
Alpha-fetoprotein 4.9
Cu/Zn superoxide dismutase 4.8
FMLP 4.8
creatine kinase 4.8
more...
Disease
vitamin E deficiency 15.1
Dietetic microangiopathy 15.1
Steatitis 14.1
Brown bowel syndrome 13.9
Nutritional muscular dystrophy 13.5
Exudative diathesis 13.5
Detergent sensitivity 13.1
ATLD 13.1
SCAE 13.1
Spastic ataxia 12.8
tocopherol deficiency 12.6
DYT15 12.5
Early Onset Cerebellar Ataxia 12.5
Pseudo-Bartter syndrome 12.3
IOSCA 12.3
Pansteatitis 12.3
VED 12.2
SANDO 11.8
Mitochondrial neurogastrointestinal encephalopathy 11.5
chylomicron retention disease 11.4
MILS 11.0
Selenium deficiency 11.0
Neuroaxonal dystrophy 10.5
Spinocerebellar degeneration 10.3
Zieve's syndrome 10.3
AOA2 10.2
hypobetalipoproteinemia 10.0
white muscle disease 10.0
Distemper 10.0
calorie deficiency 9.9
DYT11 9.8
Friedreich's ataxia 9.8
Thiamine-responsive megaloblastic anemia 9.8
FRDA 9.7
Cholestatic liver disease 9.6
hepatosis 9.6
encephalomalacia 9.6
TTP 9.6
lipoproteinemia 9.5
avitaminosis 9.5
lipoprotein disorder 9.4
Channelopathies 9.4
acanthocytosis 9.4
cholestatic cirrhosis 9.0
TTP 9.0
paraphimosis 9.0
Cerebellar atrophy 9.0
Refsum disease 8.9
retroviral disease 8.8
basal ganglia disease 8.8
hereditary ataxia 8.7
malabsorption 8.7
riboflavin deficiency 8.5
steatorrhea 8.4
McLeod syndrome 8.4
vitamin C deficiency 8.4
hypovitaminosis 8.4
Chronic progressive external ophthalmoplegia 8.2
vitamin K deficiency 8.1
Werdnig-Hoffmann disease 8.0
lymphangiosarcoma 8.0
ABL 8.0
HDL1 7.9
vitamin A deficiency 7.8
tropical sprue 7.7
hypervitaminosis 7.7
Keshan disease 7.7
cerebellar syndrome 7.6
nutritional disorder 7.4
MERRF 7.4
pancreatic insufficiency 7.3
vitamin B6 deficiency 7.2
choline deficiency 7.2
iatrogenic disease 7.1
lipidosis 7.1
myopathy 7.0
CHAC 7.0
beriberi 6.9
Zinc deficiency 6.9
short bowel syndrome 6.9
xanthomatosis 6.9
diabetic angiopathy 6.9
AOS 6.9
Vascular lesions 6.8
apraxia 6.8
Copper deficiency 6.7
retinitis pigmentosa 6.7
cholestasis 6.6
retinopathy of prematurity 6.6
Whipple's disease 6.6
sensory neuropathy 6.6
biliary atresia 6.6
PGS 6.6
peripheral neuropathy 6.5
MSS 6.5
SCA1 6.5
APOB 6.5
muscular dystrophy 6.5
sideroblastic anemia 6.5
AOA 6.4
Multiple system atrophy 6.4
DYT1 6.3
Machado-Joseph disease 6.3
night blindness 6.2
MELAS 6.2
Leigh syndrome 6.1
thrombocytosis 6.1
Lower limb 6.1
hereditary motor and sensory neuropathy 6.1
hypersplenism 6.1
Diaphragm 6.1
hemangiosarcoma 6.1
Tangier disease 6.0
mitochondrial myopathy 6.0
coxsackievirus 6.0
macrocytic anemia 5.9
MELAS 5.9
hypertension in pregnancy 5.9
vitamin B12 deficiency 5.8
Common variable immunodeficiency 5.8
primary biliary cirrhosis 5.8
obstructive airway disease 5.8
AEM 5.8
megaloblastic anemia 5.8
Kearns-Sayre syndrome 5.8
polyneuropathy 5.7
neuromuscular disorder 5.7
chest infection 5.7
bronchopulmonary dysplasia 5.7
Overweight and obesity 5.7
Dystonia 5.6
pernicious anemia 5.6
Gaucher disease 5.5
OHD 5.5
hemolytic anemia 5.5
cystic fibrosis 5.5
Spinocerebellar ataxia 5.5
nephrosis 5.5
pulmonary insufficiency 5.5
PDC 5.4
CLN3 5.4
folate deficiency 5.4
kwashiorkor 5.4
failure to thrive 5.3
cryoglobulinemia 5.3
Hypertrophic 5.3
RDA 5.3
polycythemia 5.3
neuropathy 5.3
ACD 5.3
pica 5.3
hyperoxaluria 5.3
Leber's hereditary optic neuropathy 5.2
malnutrition 5.2
vitamin D deficiency 5.2
premenstrual syndrome 5.2
motor neuron disease 5.2
CDA 5.1
intellectual impairment 5.1
Testis 5.1
more...
Symptom
ataxia 8.3
cerebellar ataxia 7.8
Physical findings 6.7
dysarthria 6.5
hypoproteinemia 6.5
emaciation 6.0
hyperoxia 5.9
ophthalmoplegia 5.7
dysesthesia 5.2
abnormal gait 4.9
dystonia 4.6
incoordination 4.3
weakness 4.3
paresis 4.2
chorea 4.0
myoclonus 4.0
spasticity 4.0
hepatosplenomegaly 4.0
tremor 3.9
bradykinesia 3.9
splenomegaly 3.8
acute abdomen 3.5
exertional dyspnea 3.4
diarrhea 3.1
anorexia 2.9
paresthesia 2.8
lethargy 2.6
hepatomegaly 2.6
hypotonia 2.6
respiratory distress 2.4
hypercapnia 2.1
hypothermia 2.0
syncope 1.9
dizziness 1.8
constipation 1.8
nausea 1.6
overweight 1.4
functional recovery 1.4
exhaustion 1.3
collapse 1.3
acidity 1.2
seizures 1.1
chest pain 1.0
angina 0.7
discomfort 0.6
discomfort 0.5
anesthesia 0.3
abdominal pain 0.2
vomiting 0.1
fatigue -0.6
pain -1.9
Drug
Anoxomer 15.1
Vitamin-E 10.8
Vitamin E 10.6
vitamin E 10.4
Pentane 10.1
Tocopherol 9.3
Liposyn 8.3
Idebenone 8.2
RbCl 7.0
RbCl 7.0
Vitamin A 6.7
SBT 6.5
Singular 6.1
linolenate 5.9
ascorbate 5.5
Riboflavin 5.5
Photofrin 5.2
niacin 5.2
Serum albumin 4.8
Vitamin B12 4.8
Vitamin B 4.8
Scopolamine 4.7
Lovastatin 4.7
Glutathione 4.7
NaI 4.3
NaI 4.3
NaI 4.3
NaI 4.3
ALA 3.6
NADH 3.5
Retinoic acid 3.4
EPA 3.3
Adriamycin 2.9
Bifidobacterium 2.6
Spectrum 2.1
nitroglycerin 2.0
lysine 1.8
Nephron 1.5
Gel 1.2
MAP 1.1
lactose 1.1
Nephron 1.0
ROS 0.9
Leaf 0.7
IFN-gamma 0.3
IL-2 0.3
Dermatol -2.9
Enzyme
SRR 10.0
Delta6-desaturase 9.1
D-amino-acid oxidase 7.9
phospholipid hydroperoxide glutathione peroxidase 7.6
NAO 7.6
biotinidase 7.5
Lod 7.5
glutamic dehydrogenase 7.3
propionyl-CoA carboxylase 6.7
propionyl-CoA carboxylase 6.7
ficin 6.6
cathepsin H 6.6
beta-hydroxybutyrate dehydrogenase 6.5
methylmalonyl-CoA mutase 6.4
phospholipase A1 6.4
carnitine acetyltransferase 6.4
glutathione peroxidase 6.2
acyl-CoA oxidase 6.2
TGT 6.1
pyruvate kinase 6.1
NADH-cytochrome b5 reductase 6.0
cytochrome P-450scc 5.9
15-lipoxygenase 5.9
prostaglandin synthetase 5.8
15-hydroxyprostaglandin dehydrogenase 5.8
neutral sphingomyelinase 5.7
acyl-CoA dehydrogenase 5.5
GABA transaminase 5.4
12-lipoxygenase 5.3
glutathione reductase 5.3
succinic dehydrogenase 5.3
LasR 5.3
cholesterol esterase 5.2
CYP7A1 5.1
PTPase 5.1
DOPA decarboxylase 5.1
creatine kinase 5.0
pyruvate dehydrogenase 4.9
pyruvate dehydrogenase 4.9
lecithin:cholesterol acyltransferase 4.9
uricase 4.8
acyl-CoA dehydrogenase 4.6
gamma-glutamylcysteine synthetase 4.6
aldehyde dehydrogenase 4.6
aldehyde dehydrogenase 4.6
TOR 4.6
aldehyde dehydrogenase 4.6
glucose-6-phosphatase 4.5
aryl hydrocarbon hydroxylase 4.4
aldehyde dehydrogenase 4.3
aldolase 4.3
lipoxygenase 4.3
tryptophan hydroxylase 4.3
aspartate aminotransferase 4.3
pyruvate dehydrogenase 4.2
demethylase 4.2
superoxide dismutase 4.1
cholesterol acyltransferase 4.1
acid phosphatase 4.0
aldehyde dehydrogenase 4.0
glutamate dehydrogenase 4.0
glutamate dehydrogenase 4.0
matrix metalloproteinase 9 4.0
glutamate dehydrogenase 4.0
matrix metalloproteinase 2 3.9
glucose-6-phosphate dehydrogenase 3.7
peroxiredoxin 3.7
MDP 3.7
beta-glucosidase 3.6
phospholipase A2 3.6
catalase 3.6
alanine aminotransferase 3.5
isocitrate dehydrogenase 3.5
5'-nucleotidase 3.5
glutathione S-transferase 3.4
beta-glucosidase 3.4
isocitrate dehydrogenase 3.3
lactate dehydrogenase 3.3
NADPH-diaphorase 3.2
succinate dehydrogenase 3.1
cathepsin B 3.1
xanthine oxidase 3.1
citrate synthase 3.0
malate dehydrogenase 2.9
IKK 2.8
glutamine synthetase 2.8
NADPH oxidase 2.8
NADPH oxidase 2.6
diaphorase 2.6
AST 2.5
NQO1 2.5
caspase-1 2.5
CYP3A4 2.4
lipoprotein lipase 2.3
MAP 2.2
thymidine kinase 2.2
beta-glucuronidase 2.2
NO synthase 2.1
cytochrome oxidase 2.0
gamma-glutamyl transpeptidase 1.9
alcohol dehydrogenase 1.9
peroxidase 1.9
transcriptase 1.9
adenylate cyclase 1.9
thrombin 1.6
cholinesterase 1.5
thromboplastin 1.4
P-glycoprotein 1.4
tyrosine hydroxylase 1.2
ATPase 1.1
protein kinase C 1.1
DNA polymerase 1.0
trypsin 0.7
lysozyme 0.7
alkaline phosphatase 0.5
acetylcholinesterase 0.3
reverse transcriptase 0.1
RNA polymerase -0.0
caspase-3 -0.0
protein kinase -0.2
mitogen-activated protein kinase -1.5
Compound
Nodakenin 12.5
Vitamin E 10.5
Nitro blue tetrazolium 10.2
DPPD 10.1
Centrophenoxine 10.0
alpha-CEHC 10.0
alpha-Tocopherol 9.9
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
selenous acid 9.6
Centrophenoxine 9.2
Ethoxyquin 9.1
TTP 8.6
beta-tocopherol 8.6
4-Hydroxynonenal 8.1
Thromboxane B2 8.0
Tocopherols 8.0
8-hydroxyguanosine 7.4
Probucol 7.4
Potassium chloride 7.3
selenium 7.1
Methoxamine 7.1
Acridine Orange 7.1
Acridine Orange 7.1
Acridine Orange 7.1
Leupeptin 7.0
Menaquinone 6.9
Nitrofurantoin 6.9
Fluvastatin 6.7
BHA 6.7
Vitamin A 6.7
coenzyme Q10 6.7
Leupeptin 6.6
1,1,1-trichloroethane 6.6
Pyridoxine 6.5
Malondialdehyde 6.5
Triton WR-1339 6.5
12-hydroxyeicosatetraenoic acid 6.4
FB2 6.4
TGT 6.4
ubiquinol 6.3
octanal 6.3
octanal 6.3
SP-1 6.3
retinol 6.1
pentane 6.1
BHT 6.1
BHC 6.1
TXA2 6.0
Rhodamine 123 6.0
IPN 5.9
Thiobarbituric acid 5.9
Coenzyme Q10 5.9
butanal 5.8
CoQ 5.8
1,3,5-hexatriene 5.7
1,3,5-hexatriene 5.7
1,3,5-hexatriene 5.7
hexanal 5.6
Tiron 5.6
Lovastatin 5.6
Ascorbic acid 5.6
hexanal 5.6
Inulin 5.5
Menadione 5.5
Nembutal 5.5
Riboflavin 5.4
CCl4 5.4
Docosahexaenoic acid 5.4
Brefeldin A 5.4
Brefeldin A 5.4
Lac 5.3
2-butanone 5.3
CDA 5.2
ATF 5.2
Tween 20 5.1
Creatine 5.0
Staurosporine 5.0
GSSG 4.9
ATA 4.9
FMLP 4.9
nonyl 4.9
p-cresol 4.9
Staurosporine 4.9
Linoleic acid 4.9
Parenteral 4.8
Arachidonic acid 4.8
1,2-dimethylhydrazine 4.7
TTS 4.7
Lip 4.6
Acetone 4.6
Mato 4.6
Pentobarbital 4.6
tellurium 4.6
SO3 4.6
BUdR 4.6
prostacyclin 4.5
GSH 4.5
GSH 4.5
Inositol 4.4
TAP 4.4
cyclohexanone 4.3
p-cresol 4.3
Dopa 4.3
Chloroquine 4.2
Chloroquine 4.2
hydroxyindoleacetic acid 4.2
Methionine 4.1
1-chloro-2,4-dinitrobenzene 4.1
acetate 4.0
prostaglandin F2alpha 4.0
DHA 4.0
DHA 4.0
succinic acid 4.0
succinic acid 4.0
succinic acid 4.0
succinic acid 4.0
rubidium 4.0
BCNU 3.9
DHA 3.9
Hemoglobin 3.9
GPT 3.9
L-leucine 3.8
SEE 3.8
Lactic acid 3.7
Hearts 3.7
LTC4 3.6
MDA 3.5
vitamin D 3.5
NADH 3.5
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine 3.4
5-hydroxytryptophan 3.4
ANS 3.4
ANS 3.4
iron 3.3
succinic acid 3.3
NADPH 3.3
NADPH 3.3
EPA 3.3
noradrenaline 3.2
propylene glycol 3.2
2-oxoglutarate 3.2
STZ 3.2
homocysteine 3.2
propylene glycol 3.1
2-mercaptoethanol 3.1
Adriamycin 3.1
Adrenal 3.0
stearic acid 3.0
stearic acid 3.0
PGA 2.9
stearic acid 2.9
Hearts 2.8
tryptophan 2.8
MPTP 2.7
acetyl-CoA 2.7
NADP 2.6
tryptophan 2.6
more...