Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042875 (
vitamin E deficiency
)
916
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
The significance of selenium deficiency was investigated in pigs that died suddenly of microangiopathy (
MAP
, mulberry heart disease). Hepatic selenium concentration (mean +/- SD) in pigs with
MAP
(1.04 +/- 0.47 micrograms/g dry weight) was lower than in healthy pigs (1.23 +/- 0.53 micrograms/g). The lowest hepatic selenium values were found in pigs with
MAP
and in 22.2% of
MAP
pigs hepatic selenium concentration was below 0.5 microgram/g which reflects selenium deficiency. Thus, pigs with a low selenium status are at risk of
MAP
. The low selenium status together with
vitamin E deficiency
increases oxidative stress and thus contributes to the development of oxidative damage.
...
PMID:Hepatic selenium concentration in pigs with microangiopathy (mulberry heart disease)--an animal model for the study of oxidative damage. 221 Sep 65
