Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042755 (masculinization)
 2,562 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

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Human Gene/Protein
SCAMP1 protein 13.6
MYH10 protein 12.6
mitochondrial ribosomal protein S27 12.6
steroid 21-hydroxylase, CYP21 12.6
TTC27 12.6
tubulin-specific chaperone A 11.6
FEM1A 10.8
WNT-4 10.7
RPL37 10.6
RPL17 10.5
CXorf6 10.4
CYP21A2 10.3
LARP 10.1
HSD3 10.1
CYP21 10.1
Mog 10.0
ZNF216 10.0
17-ketoreductase 10.0
HSD17B3 10.0
21-hydroxylase 9.7
SRD5A2 9.6
steroid 21-hydroxylase 9.6
POF1 9.5
DAZ1 9.5
HEMGN 9.4
cytochrome P450 21-hydroxylase 9.4
steroid 5 alpha-reductase 9.3
P450c21 9.3
HSD3B2 9.3
SCAMP1 9.2
SCAMP 9.1
PPSH 9.1
17-beta-hydroxysteroid dehydrogenase 9.1
PAIS 9.1
NANOS3 8.9
Ad4BP 8.7
CYP11B1 8.7
Mullerian inhibiting substance 8.7
mago 8.7
NR5A1 8.7
RSPO1 8.6
prostaglandin reductase 1 8.6
RPS4Y 8.6
ALG6 8.5
Prokineticin 2 8.5
cytochrome P450c 8.5
DMRT1 8.5
20alpha-hydroxysteroid dehydrogenase 8.4
POPX2 8.4
17 beta-hydroxysteroid dehydrogenase 8.4
HSD17B12 8.4
CUL-2 8.4
PG8 8.3
GAPDS 8.3
NANOS2 8.3
P450C17 8.3
sex-determining region Y 8.1
spinophilin 8.1
testican 8.1
SRD5A1 8.1
TSPY 8.1
WNT4 8.1
desert hedgehog 8.1
MYH10 8.0
ciliary neurotrophic factor receptor 8.0
SRY 8.0
PRKRA 8.0
Leydig cell 8.0
FGF12 8.0
CYP11A 8.0
ZFY 7.9
FOG2 7.8
delta 4 7.8
HSD17B2 7.8
Ctr9 7.7
FHI 7.7
HSD17B1 7.7
cullin 1 7.7
AMH 7.6
CYP19A1 7.6
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Disease
Masculinization of female 13.6
trisomy Xq 13.2
Aromatase deficiency 12.8
Female pseudohermaphroditism 12.8
Arrhenoblastoma 12.6
Deficiency of 3beta-hydroxysteroid dehydrogenase 12.6
Steroid cell tumor 12.4
Feminization of male 12.3
Adrenocortical Tumor 12.3
17-KSR deficiency 12.0
Central hypogonadism 12.0
Bixler syndrome 12.0
Sex differentiation disorders 12.0
Male pseudohermaphroditism 11.8
luteoma 11.6
Freemartin 11.6
Sertoli cell tumor of testis 11.3
Testotoxicosis 11.3
Mixed gonadal dysgenesis 11.3
Other endocrine disorders 11.3
17,20-desmolase deficiency 11.1
Gynandroblastoma 11.0
Sertoli-Leydig cell tumor 10.8
Sertoli-Leydig cell tumor 10.8
5-alpha reductase deficiency 10.8
Clitoris 10.8
fertile eunuch syndrome 10.8
21-hydroxylase deficiency 10.8
11 beta-hydroxylase deficiency 10.7
Premature adrenarche 10.7
Reifenstein syndrome 10.6
congenital adrenal hyperplasia 10.5
Steroid 21-hydroxylase deficiency 10.5
external genitalia 10.5
Androgen excess 10.5
Infantile acne 10.4
Precocious pubarche 10.4
ACTH-producing pituitary tumor 10.1
3 beta-HSD deficiency 10.1
Secondary adrenal insufficiency 10.0
Gender dysphoria 9.7
Premature pubarche 9.7
neoplasm of uncertain malignant potential 9.7
nymphomania 9.6
Leydig cell insufficiency 9.6
Krukenberg tumor 9.6
Adrenal myelolipoma 9.5
Strumal carcinoid 9.5
Leydig cell hyperplasia 9.5
Leydig cell tumor 9.5
testicular feminization 9.5
Leydig cell hypoplasia 9.5
17-alpha-hydroxylase deficiency 9.4
gonadoblastoma 9.4
thecoma 9.4
Sclerosing stromal tumor 9.4
hyperandrogenism 9.2
adrenal neoplasm 9.2
XX males 8.9
Maternal phenylketonuria 8.8
adrenocortical carcinoma 8.8
Juvenile granulosa cell tumor 8.7
Adrenal suppression 8.7
primary amenorrhea 8.7
OHD 8.6
Swyer syndrome 8.6
secondary amenorrhea 8.6
adrenal disorder 8.6
adrenal hyperplasia 8.6
gonadal dysgenesis 8.6
HHG 8.5
Mucinous cystadenoma 8.5
metastatic adrenocortical carcinoma 8.4
adrenal adenoma 8.4
granulosa cell tumor 8.4
Kennedy syndrome 8.4
Hypothalamic hamartoma 8.2
precocious puberty 8.2
gynecomastia 8.2
XY females 8.2
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Symptom
masculinization 13.6
scant menses 13.6
Coarse hair 12.6
Frontal headache 12.0
increased abdominal size 10.8
absent menses 10.3
Massive edema 9.7
Balding 9.6
Cushingoid 9.0
intermenstrual pain 9.0
Cushingoid 9.0
testicular lump 8.7
Intermenstrual bleeding 8.6
POA 8.1
unable to conceive 8.0
voice change 7.3
menometrorrhagia 7.3
male puberty 7.2
chromosome marker 6.5
Deafferentation 6.2
hot flashes 5.1
mastalgia 5.0
Spots 4.8
hoarseness 4.7
stomach pain 4.6
anosmia 4.6
excessive sweating 4.4
Fluctuation 4.4
hot flushes 4.3
CSR 4.2
physical appearance 4.0
dry skin 3.6
night sweats 3.4
abdominal pain 3.3
pelvic pain 3.2
acute abdomen 3.0
despair 2.9
exertional dyspnea 2.9
leg pain 2.6
chorea 2.6
flushing 2.5
pallor 2.3
nausea 2.3
cachexia 2.1
polyuria 2.0
bone pain 2.0
nausea and vomiting 2.0
dysarthria 1.7
vomiting 1.6
discomfort 1.5
dizziness 1.4
discomfort 1.3
ENT 1.2
thinning 1.1
lethargy 1.1
myalgia 0.9
anorexia 0.8
fatigue 0.7
acidity 0.7
overweight 0.5
distraction 0.4
low back pain 0.3
Ill 0.2
agitation 0.0
erythema -0.1
headache -0.2
Welt -0.4
hypothermia -0.5
anesthesia -0.6
weakness -0.6
respiratory distress -0.7
pain -0.7
angina -0.8
cough -0.9
seizures -1.1
collapse -1.2
Drug
Ogen 10.3
Factrel 10.1
Trenbolone acetate 9.8
Andriol 9.4
Dihydrotestosterone 8.6
Drospirenone 8.4
Gestodene 7.8
Cortrosyn 7.6
Sesame oil 7.5
Cortrosyn 7.4
R1881 7.3
TES 7.0
Ddc 7.0
Ipriflavone 6.6
Lisuride 6.5
Pregnenolone 6.4
Estrogens 6.4
Premarin 6.3
DHT 6.2
DHT 6.1
Levonorgestrel 6.1
HCG 5.7
Guanethidine 5.5
EE2 5.3
Zoladex 5.3
AC2 5.2
Luteinizing 5.2
Finasteride 4.8
Troglitazone 4.5
Norplant 4.4
VCR 4.3
Kainic acid 4.3
Norplant 3.9
Kenyan 3.8
Reserpine 3.6
Prednisone 3.6
IL-11 3.5
DMAP 3.5
RFP 3.4
Vitamin B12 3.3
MAP 3.1
VCR 3.0
CPR 2.9
ICI 2.8
PCB 2.6
ACT 2.5
Forskolin 2.2
ETS 2.2
Growth hormone 2.1
Growth hormone 2.0
Indomethacin 2.0
HCH 1.8
Spectrum 1.6
ENT 1.5
Adriamycin 1.4
Asn 1.1
Mutagen 1.1
Spectrum 0.7
Ethanol 0.3
CTX 0.3
Nephron -0.5
caffeine -0.8
Dermatol -0.9
Asthma -1.0
CSF -1.3
lysine -2.2
Enzyme
cortisone alpha-reductase 12.6
3(17)alpha-hydroxysteroid dehydrogenase 11.0
21-hydroxylase 9.7
17-ketoreductase 9.6
steroid sulfotransferase 8.6
5alpha-reductase 8.4
5alpha-reductase 8.3
17beta-HSD 7.9
20beta-hydroxysteroid dehydrogenase 7.9
3beta-hydroxysteroid dehydrogenase 7.8
20alpha-hydroxysteroid dehydrogenase 7.6
Lod 7.6
17beta-HSD 7.5
5beta-reductase 7.4
cytochrome P-450scc 6.8
HSD 6.5
3alpha-hydroxysteroid dehydrogenase 6.1
estrogen sulfotransferase 5.7
11beta-hydroxysteroid dehydrogenase 5.3
AGT 5.0
CGT 4.8
STK11 4.7
TGT 4.6
estrogen sulfotransferase 4.5
PDH 4.2
cholesterol oxidase 4.2
GCA 4.2
E-2 4.1
acyl-CoA oxidase 3.7
flavin-containing monooxygenase 3.5
arylsulfatase 3.4
prostate-specific antigen 3.2
deoxyribonuclease 3.1
deoxyribonuclease 3.0
triphosphatase 3.0
sulfatase 3.0
renin 2.9
PRA 2.9
phosphoglucose isomerase 2.9
NOS 2.8
chloramphenicol acetyltransferase 2.3
choline acetyltransferase 2.0
luciferase 1.8
monoamine oxidase 1.8
glyceraldehyde-3-phosphate dehydrogenase 1.5
glyceraldehyde-3-phosphate dehydrogenase 1.5
glyceraldehyde-3-phosphate dehydrogenase 1.4
phospholipase A2 1.4
DNA methyltransferase 1.3
CPR 1.2
demethylase 1.2
glyceraldehyde-3-phosphate dehydrogenase 1.1
kallikrein 1.0
NQO1 1.0
ornithine decarboxylase 1.0
glyceraldehyde-3-phosphate dehydrogenase 0.9
ribonuclease 0.9
ribonuclease 0.9
lipoprotein lipase 0.8
tyrosine hydroxylase 0.8
DNase 0.7
succinate dehydrogenase 0.6
cytochrome oxidase 0.5
gamma-glutamyl transpeptidase 0.5
alcohol dehydrogenase 0.4
endonuclease 0.4
acetylcholinesterase 0.4
glutathione reductase 0.4
protein kinase 0.1
trypsin -0.2
focal adhesion kinase -0.2
RNase -0.4
RNase -0.5
ACE -0.6
catalase -0.6
peroxidase -0.8
glutathione S-transferase -0.9
alkaline phosphatase -0.9
reverse transcriptase -1.4
ERK -1.4
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Compound
tris(2,6-dimethylphenyl) phosphate 13.6
Norethandrolone 9.9
Trenbolone 9.7
Mibolerone 9.5
Testolactone 9.0
17-OHP 9.0
17alpha-hydroxypregnenolone 8.7
Diisononyl phthalate 8.7
Androstenediol 8.7
Dianabol 8.5
Infecundin 8.5
Adiol 8.5
Fenarimol 8.4
Cosyntropin 8.4
Norethisterone acetate 8.4
androstan-3-one 8.3
Androgen 8.2
Norethisterone 7.9
Androstenedione 7.8
Mestranol 7.7
Letrozole 7.7
Desogestrel 7.7
Prochloraz 7.6
Dianabol 7.5
POA 7.5
Vinclozolin 7.4
CI-628 7.3
CI-628 7.3
1-amino-1,3-cyclopentanedicarboxylic acid 7.3
Testosterone 7.3
Testosterone 7.3
Norgestrel 7.2
Nandrolone 7.2
Stanozolol 7.0
ED 20 7.0
Hydrocortisone acetate 7.0
Stanozolol 6.9
DHT 6.9
Stanozolol 6.9
4-octylphenol 6.9
Levonorgestrel 6.8
Fludrocortisone 6.8
Cyproterone acetate 6.6
Bifenthrin 6.6
Astemizole 6.6
NEA 6.5
FTA 6.5
Danazol 6.5
Pregnenolone 6.4
Methoxychlor 6.4
Premarin 6.3
Dehydroepiandrosterone sulfate 6.3
Oxazepam 6.2
TMF 6.2
MPT 6.2
androstane 6.2
Metyrapone 6.1
Metyrapone 6.1
TBT 6.1
Clomiphene 6.1
C12H8N2 6.0
diisobutyl phthalate 6.0
o,p'-DDD 6.0
DBCP 5.8
ACTH 5.7
Geigy 5.7
Spironolactone 5.7
Saccharin 5.6
Guanethidine 5.6
HCP 5.5
FBF 5.5
Miconazole 5.5
Premarin 5.5
Organon 5.4
DES 5.4
PH2 5.4
DHA 5.4
Betamethasone 5.2
Adrenal 5.2
TTA 5.2
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