Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042755 (masculinization)
 2,562 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
androgen receptor 187
Sep 177
aromatase 140
Mol 118
ACTH 85
reductase 79
Leydig cell 76
21-hydroxylase 72
She 68
Y chromosome 63
FSH 61
insulin 50
chorionic gonadotropin 46
SRY 42
CYP21 41
estrogen receptor 40
Gen 36
CYP21A2 35
delta 4 30
Aromatase 27
X-linked 26
LHRH 26
P450 25
HSD 25
steroid 21-hydroxylase 23
follicle-stimulating hormone 23
p53 22
renin 22
HLA 22
growth hormone 21
beta-endorphin 19
prolactin 19
olfactory 18
CYP11B1 17
sex hormone-binding globulin 16
cytochrome P450 15
MRI 15
oxidoreductase 15
SRD5A2 14
P450scc 14
more...
Disease
tumor 342
congenital adrenal hyperplasia 305
external genitalia 255
21-hydroxylase deficiency 145
cancer 105
hyperandrogenism 102
Cushing's syndrome 97
hypertension 75
infertility 69
wasting 67
acne 67
polycystic ovary syndrome 65
adrenocortical carcinoma 60
precocious puberty 54
uterus 54
gynecomastia 49
amenorrhea 49
carcinoma 42
obesity 40
adenoma 40
gonadal dysgenesis 38
scrotum 38
aggression 38
vagina 36
testicular feminization 35
diabetes 34
Turner syndrome 34
hypogonadism 34
metastases 34
primary amenorrhea 33
urethra 31
secondary amenorrhea 30
adrenal insufficiency 29
adrenal hyperplasia 29
hypogonadotropic hypogonadism 28
Sertoli-Leydig cell tumor 28
stromal tumors 27
gonadoblastoma 27
Sertoli-Leydig cell tumor 27
Leydig cell tumor 26
more...
Symptom
masculinization 2562
abdominal pain 25
pain 13
POA 12
Cushingoid 9
Cushingoid 9
nausea 9
vomiting 8
fatigue 7
anesthesia 6
hoarseness 6
discomfort 5
discomfort 5
headache 4
seizures 3
flushing 3
anosmia 3
hot flashes 3
nausea and vomiting 3
overweight 3
pelvic pain 3
acute abdomen 2
exertional dyspnea 2
physical appearance 2
menometrorrhagia 2
acidity 2
hot flushes 2
thinning 2
anorexia 2
voice change 2
weakness 2
dizziness 2
Balding 2
cachexia 2
scant menses 1
excessive sweating 1
collapse 1
distraction 1
Deafferentation 1
increased abdominal size 1
more...
Drug
EE2 25
Estrogens 15
DHT 13
Dihydrotestosterone 13
DHT 13
Dermatol 11
HCG 11
MAP 11
R1881 8
TES 6
Kenyan 4
ICI 3
Norplant 3
Levonorgestrel 3
Trenbolone acetate 3
Luteinizing 3
Drospirenone 2
PCB 2
Premarin 2
Indomethacin 2
Pregnenolone 2
Asn 2
ENT 2
Andriol 2
Cortrosyn 1
Spectrum 1
Vitamin B12 1
Finasteride 1
ETS 1
ACT 1
DMAP 1
Kainic acid 1
Zoladex 1
Sesame oil 1
Asthma 1
VCR 1
Adriamycin 1
Guanethidine 1
Growth hormone 1
Lisuride 1
more...
Enzyme
21-hydroxylase 79
5alpha-reductase 29
5alpha-reductase 28
HSD 25
renin 22
3beta-hydroxysteroid dehydrogenase 17
luciferase 11
protein kinase 7
17beta-HSD 5
prostate-specific antigen 5
cytochrome P-450scc 5
17beta-HSD 4
NOS 4
11beta-hydroxysteroid dehydrogenase 4
phospholipase A2 3
ERK 3
focal adhesion kinase 3
Lod 3
acetylcholinesterase 3
catalase 3
mitogen-activated protein kinase 3
trypsin 3
monoamine oxidase 3
peroxidase 3
alkaline phosphatase 2
20alpha-hydroxysteroid dehydrogenase 2
chloramphenicol acetyltransferase 2
AGT 2
tyrosine hydroxylase 2
sulfatase 2
20beta-hydroxysteroid dehydrogenase 2
choline acetyltransferase 2
endonuclease 2
deoxyribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
steroid sulfotransferase 1
triphosphatase 1
glyceraldehyde-3-phosphate dehydrogenase 1
DNase 1
more...
Compound
Clin 257
Dec 178
DNA 123
salt 101
ACTH 85
Testosterone 75
Testosterone 75
Androgen 71
water 50
sulfate 49
acetate 44
aldosterone 42
17-OHP 32
Estrogen 27
DHT 26
Adrenal 25
DHA 22
Androstenedione 18
glucose 17
Estrogen 17
His 17
Dexamethasone 15
sodium 15
Estradiol 15
arginine 13
Cortisol 12
glutamine 12
cAMP 12
POA 12
Progesterone 10
COS 10
ethanol 9
FTA 9
androstane 9
Insulin 8
DBP 8
alanine 7
potassium 7
glutamate 7
threonine 7
more...