Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042755 (masculinization)
 2,562 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
androgen receptor 187
Sep 177
aromatase 140
Mol 118
ACTH 85
reductase 79
Leydig cell 76
21-hydroxylase 72
She 68
Y chromosome 63
FSH 61
insulin 50
chorionic gonadotropin 46
SRY 42
CYP21 41
estrogen receptor 40
Gen 36
CYP21A2 35
delta 4 30
Aromatase 27
LHRH 26
X-linked 26
P450 25
HSD 25
follicle-stimulating hormone 23
steroid 21-hydroxylase 23
HLA 22
renin 22
p53 22
growth hormone 21
beta-endorphin 19
prolactin 19
olfactory 18
CYP11B1 17
sex hormone-binding globulin 16
oxidoreductase 15
cytochrome P450 15
MRI 15
pseudogene 14
P450scc 14
FGF8 14
SRD5A2 14
H-Y 13
SOX9 13
17 beta-hydroxysteroid dehydrogenase 13
CYP19 13
3 beta-hydroxysteroid dehydrogenase 13
3 beta-HSD 12
spermatozoa 12
cryptic 11
vimentin 11
AMH 11
sex-determining region Y 11
HCG 11
AR protein 10
CYP19A1 10
cytokeratin 10
steroid 5 alpha-reductase 9
adrenocorticotropic hormone 9
SF-1 9
X-linked recessive 9
Androgen receptor 9
Pol 9
HSD3 9
P450c21 8
steroidogenic acute regulatory protein 8
nuclear receptor 8
NR5A1 8
microsomal 8
HSD3B2 8
ER beta 7
histone 7
sex hormone binding globulin 7
epididymal 7
HSD17B3 7
steroidogenic factor 1 7
Men 7
P450c17 7
X-chromosome 7
CYP17A1 7
DMRT1 7
alpha-fetoprotein 7
DNA-binding domain 6
progesterone receptor 6
WT1 6
HSD2 6
cytochrome 6
cytochrome P-450 6
TSPY 6
17beta-hydroxysteroid dehydrogenase 6
insulin receptor 6
glucocorticoid receptor 6
DHEAS 6
MIS 5
FISH 5
DAX1 5
FOXL2 5
estrogen receptor alpha 5
DDD 5
Ad4BP 5
zinc finger protein 5
DES 5
hedgehog 5
xenobiotic 5
ATC 5
WNT4 5
SF1 5
insulin-like growth factor I 5
prostate-specific antigen 5
thyroid hormone 5
CYP17 5
Ki-67 5
spinophilin 5
StAR 5
catenin 5
ZFY 5
leptin 5
thymus 5
fused 5
DBP 5
GSD 4
non-functional 4
angiotensin II 4
endoplasmic reticulum 4
Estrogen receptor 4
GABA 4
lymphoid 4
telomeric 4
Wnt4 4
vasopressin 4
ER-alpha 4
progranulin 4
RSPO1 4
AMP 4
beta-catenin 4
zinc finger 4
luteinizing hormone receptor 4
CA1 4
cyclooxygenase 4
calretinin 4
PIWI 4
calbindin 4
AE1 4
D. melanogaster 4
SDS 4
Hop 4
C21 4
TRA 4
kisspeptin 4
fruitless 4
synaptophysin 4
threonine 4
CYP11A 4
CYP11A1 4
Beckwith-Wiedemann syndrome 4
CYP11B2 3
ATF3 3
ubiquitin 3
PAIS 3
Sex hormone-binding globulin 3
more...
Disease
tumor 342
congenital adrenal hyperplasia 305
external genitalia 255
21-hydroxylase deficiency 145
cancer 105
hyperandrogenism 102
Cushing's syndrome 97
hypertension 75
infertility 69
wasting 67
acne 67
polycystic ovary syndrome 65
adrenocortical carcinoma 60
precocious puberty 54
uterus 54
amenorrhea 49
gynecomastia 49
carcinoma 42
obesity 40
adenoma 40
gonadal dysgenesis 38
aggression 38
scrotum 38
vagina 36
testicular feminization 35
metastases 34
hypogonadism 34
Turner syndrome 34
diabetes 34
primary amenorrhea 33
urethra 31
secondary amenorrhea 30
adrenal insufficiency 29
adrenal hyperplasia 29
hypogonadotropic hypogonadism 28
Sertoli-Leydig cell tumor 28
Sertoli-Leydig cell tumor 27
gonadoblastoma 27
stromal tumors 27
Leydig cell tumor 26
luteoma 26
epididymis 25
OHD 24
adrenal adenoma 21
chronic active hepatitis 21
breast cancer 20
AIS 19
depression 18
seminal vesicles 18
hypercortisolism 18
dysphoria 17
granulosa cell tumor 16
osteoporosis 16
hyperinsulinemia 16
enzyme deficiency 16
hermaphroditism 16
azoospermia 16
acanthosis nigricans 16
prostate cancer 15
malnutrition 14
genetic disorder 14
adrenal mass 14
11 beta-hydroxylase deficiency 13
confusion 12
Ovary 12
glucose intolerance 12
adenocarcinoma 12
HCG 12
Leydig cell hyperplasia 11
hypothyroidism 11
ovarian cysts 11
dysgerminoma 11
autism 11
delayed puberty 11
Cushing's disease 11
abortion 11
aldosteronism 11
Best 10
Krukenberg tumor 10
Steroids 10
WT1 10
seborrheic dermatitis 9
thecoma 9
metabolic syndrome 9
hyperprolactinemia 9
Testis 9
Testis 9
acne vulgaris 9
Conn 9
rare disease 8
male infertility 8
aggressiveness 8
tumorigenesis 8
anovulation 8
XX males 8
dysplasia 8
Aromatase deficiency 8
benign tumor 7
teratoma 7
hernia 7
choriocarcinoma 7
Testes 7
endometrial hyperplasia 7
ovarian neoplasm 7
Reifenstein syndrome 7
Beckwith-Wiedemann syndrome 6
type 2 diabetes 6
galactorrhea 6
Male pseudohermaphroditism 6
cold 6
SEM 6
hypertrichosis 6
Androgen excess 6
inguinal hernia 6
primary tumor 6
acromegaly 6
AGA 6
Syndrome 6
sexual dysfunction 6
pheochromocytoma 6
Klinefelter's syndrome 6
Mixed gonadal dysgenesis 5
galactorrhea 5
hypopituitarism 5
mental retardation 5
Female pseudohermaphroditism 5
Addison's disease 5
DES 5
cardiovascular disease 5
goiter 5
anemia 5
carcinoid 5
Hereditary angioedema 5
Nelson 5
hypercortisolemia 5
hepatoblastoma 5
DDD 5
Steroid 21-hydroxylase deficiency 5
testicular cancer 5
endocrine disorder 5
ABS 5
endometriosis 5
mental retardation 5
mental illness 4
Premature adrenarche 4
GSD 4
mammary tumor 4
transsexualism 4
Blocking 4
Steroid cell tumor 4
hypoglycemia 4
GSD 4
hyperthyroidism 4
Adrenal myelolipoma 4
pituitary tumor 4
dehydration 4
purpura 4
ATD 4
Addison's disease 4
SDS 4
more...
Symptom
masculinization 2562
abdominal pain 25
pain 13
POA 12
nausea 9
Cushingoid 9
Cushingoid 9
vomiting 8
fatigue 7
anesthesia 6
hoarseness 6
discomfort 5
discomfort 5
headache 4
overweight 3
nausea and vomiting 3
anosmia 3
hot flashes 3
flushing 3
seizures 3
pelvic pain 3
exertional dyspnea 2
acidity 2
acute abdomen 2
anorexia 2
voice change 2
thinning 2
weakness 2
dizziness 2
Balding 2
physical appearance 2
hot flushes 2
menometrorrhagia 2
cachexia 2
Ill 1
Fluctuation 1
Massive edema 1
absent menses 1
collapse 1
despair 1
Intermenstrual bleeding 1
distraction 1
Deafferentation 1
increased abdominal size 1
intermenstrual pain 1
CSR 1
bone pain 1
respiratory distress 1
chorea 1
chromosome marker 1
agitation 1
leg pain 1
night sweats 1
Welt 1
erythema 1
cough 1
lethargy 1
stomach pain 1
scant menses 1
low back pain 1
dysarthria 1
angina 1
dry skin 1
ENT 1
unable to conceive 1
excessive sweating 1
testicular lump 1
mastalgia 1
male puberty 1
myalgia 1
pallor 1
Coarse hair 1
Spots 1
hypothermia 1
polyuria 1
Frontal headache 1
Drug
EE2 25
Estrogens 15
Dihydrotestosterone 13
DHT 13
DHT 13
MAP 11
Dermatol 11
HCG 11
R1881 8
TES 6
Kenyan 4
Luteinizing 3
ICI 3
Norplant 3
Trenbolone acetate 3
Levonorgestrel 3
Drospirenone 2
Premarin 2
Indomethacin 2
Andriol 2
Asn 2
ENT 2
Pregnenolone 2
PCB 2
Factrel 1
Spectrum 1
Vitamin B12 1
Troglitazone 1
Finasteride 1
ETS 1
ACT 1
Sesame oil 1
Asthma 1
DMAP 1
Kainic acid 1
Zoladex 1
Guanethidine 1
Adriamycin 1
Nephron 1
Growth hormone 1
Ddc 1
VCR 1
Lisuride 1
Reserpine 1
IL-11 1
AC2 1
RFP 1
Ogen 1
Forskolin 1
Norplant 1
Spectrum 1
CSF 1
Prednisone 1
Mutagen 1
Gestodene 1
VCR 1
CPR 1
Ipriflavone 1
Cortrosyn 1
Cortrosyn 1
Ethanol 1
HCH 1
Growth hormone 1
CTX 1
lysine 1
caffeine 1
Enzyme
21-hydroxylase 79
5alpha-reductase 29
5alpha-reductase 28
HSD 25
renin 22
3beta-hydroxysteroid dehydrogenase 17
luciferase 11
protein kinase 7
17beta-HSD 5
cytochrome P-450scc 5
prostate-specific antigen 5
17beta-HSD 4
11beta-hydroxysteroid dehydrogenase 4
NOS 4
monoamine oxidase 3
phospholipase A2 3
ERK 3
focal adhesion kinase 3
Lod 3
acetylcholinesterase 3
catalase 3
mitogen-activated protein kinase 3
trypsin 3
peroxidase 3
alkaline phosphatase 2
sulfatase 2
chloramphenicol acetyltransferase 2
20beta-hydroxysteroid dehydrogenase 2
tyrosine hydroxylase 2
AGT 2
20alpha-hydroxysteroid dehydrogenase 2
choline acetyltransferase 2
endonuclease 2
deoxyribonuclease 1
glyceraldehyde-3-phosphate dehydrogenase 1
PDH 1
reverse transcriptase 1
steroid sulfotransferase 1
STK11 1
5beta-reductase 1
triphosphatase 1
CPR 1
17-ketoreductase 1
glyceraldehyde-3-phosphate dehydrogenase 1
DNase 1
TGT 1
NQO1 1
cortisone alpha-reductase 1
cholesterol oxidase 1
kallikrein 1
deoxyribonuclease 1
ribonuclease 1
CGT 1
estrogen sulfotransferase 1
PRA 1
alcohol dehydrogenase 1
3(17)alpha-hydroxysteroid dehydrogenase 1
ACE 1
ATPase 1
RNase 1
protein kinase C 1
glyceraldehyde-3-phosphate dehydrogenase 1
flavin-containing monooxygenase 1
glutathione reductase 1
3alpha-hydroxysteroid dehydrogenase 1
demethylase 1
GCA 1
gamma-glutamyl transpeptidase 1
lipoprotein lipase 1
ribonuclease 1
arylsulfatase 1
succinate dehydrogenase 1
RNase 1
glutathione S-transferase 1
glyceraldehyde-3-phosphate dehydrogenase 1
glyceraldehyde-3-phosphate dehydrogenase 1
phosphoglucose isomerase 1
acyl-CoA oxidase 1
cytochrome oxidase 1
DNA methyltransferase 1
ornithine decarboxylase 1
estrogen sulfotransferase 1
E-2 1
Compound
Clin 257
Dec 178
DNA 123
salt 101
ACTH 85
Testosterone 75
Testosterone 75
Androgen 71
water 50
sulfate 49
acetate 44
aldosterone 42
17-OHP 32
Estrogen 27
DHT 26
Adrenal 25
DHA 22
Androstenedione 18
glucose 17
His 17
Estrogen 17
sodium 15
Estradiol 15
Dexamethasone 15
arginine 13
Cortisol 12
POA 12
cAMP 12
glutamine 12
Progesterone 10
COS 10
androstane 9
ethanol 9
FTA 9
DBP 8
Insulin 8
Salt 7
threonine 7
glutamate 7
5-HT 7
alanine 7
potassium 7
retinoic acid 6
PGE 6
PGE2 6
calcium 6
Bisphenol A 6
cysteine 6
methionine 6
leucine 6
Bisphenol A 6
serine 6
A 3 5
Letrozole 5
GABA 5
DDD 5
SDS 5
DBP 5
androstan-3-one 5
DES 5
GABA 4
Norethisterone 4
Danazol 4
AMPA 4
iodine 4
phosphate 4
AMP 4
nitric oxide 4
DEHP 4
valine 4
silver 4
tyrosine 4
silicon 3
Premarin 3
ICI 3
NADPH 3
Thyroid 3
NMDA 3
Dianabol 3
vitamin D 3
RU-486 3
Spironolactone 3
Isoproterenol 3
17alpha-hydroxypregnenolone 3
iron 3
TRH 3
Ile 3
NADPH 3
GTP 3
MPT 3
Trenbolone 3
DDP 2
Dopamine 2
Mibolerone 2
Primatol 2
CAT 2
Primatol 2
Levonorgestrel 2
sodium chloride 2
tin 2
Primatol 2
Optimal 2
Organon 2
gamma-aminobutyric acid 2
CAT 2
Pregnenolone 2
aldehyde 2
Adiol 2
hyaluronic acid 2
Nandrolone 2
TTA 2
Premarin 2
zinc 2
DDE 2
Vimentin 2
dUTP 2
ITP 2
NBQX 2
Cholesterol 2
LIN 2
Indomethacin 2
NAD 2
Cyproterone acetate 2
DSM 2
nitrogen 2
TBT 2
HCP 2
hydrogen 2
aldehyde 2
Metyrapone 2
o,p'-DDD 2
Cereb 2
Tamoxifen 2
DSS 2
Corticosterone 2
Metyrapone 2
CAT 2
proline 2
Tamoxifen 2
Nodular 1
Phe 1
Asp 1
CI-628 1
DDT 1
Desogestrel 1
aspartic acid 1
creatinine 1
Hearts 1
lysine 1
Cocaine 1
COX 1
ammonia 1
Fenarimol 1
Oxazepam 1
isoleucine 1
PMA 1
Reserpine 1
strontium 1
Norepinephrine 1
nicotinamide 1
more...