Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042571 (vertigo)
 7,148 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

We report a 73-year-old right-handed female who presented with an acute amnesic syndrome. On November 18, 1991, she was admitted to a local hospital complaining of sudden-onset vertigo and nausea, but immediately after the admission she developed an amnesic syndrome. On November 27, she was transferred to our hospital for further assessment of her memory disturbance. Neurologically she was normal except for mild right hemianopsia and increased deep tendon reflexes in the extremities. Neuropsychological assessments were performed over 3 weeks. She was always alert, attentive, and cooperative. She had no confabulation. On the Wechsler Adult Intelligence Scale revised (WAIS-R), her total IQ was 110. Frontal, verbal, and perceptual functions and motor performance were normal. She had no signs of a callosal disconnection. Despite these preserved functions, her memory function was obviously disturbed. Several memory betteries showed that her recent memory for both verbal and visual modalities was impaired, while her immediate memory such as digit span was preserved. For remote memory her retrograde episodic memory concerning both personal and public events was almost intact, although she had a profound anterograde amnesia. In particular she recalled her personal information about just-premorbid events in detail. On the other hand, her semantic memory, for example understanding of proverbs, geography, and scientific law, was preserved. Taken together, her procedural memory on learning tasks, such as "Tower of Hanoi" and mirror drawing, was intact. Computed tomography demonstrated a low-density area medial to the trigon of the left ventricle.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[A case of cerebral infarction presenting as retrosplenial amnesia]. 130 33

300 women aged 16-37 received analgesic-sedative preparations for miniabortions preprandially after admittance to the clinic. Anamnesis was followed by routine blood pressure check, then 0.01 mg/kg-1 atropine, 0.1 mg/kg-1 diazepam iv, or 0.05 mg/kg-1 midazolam iv was given to 25 women. 1-2 minutes later 0.5 mg/kg-1 ketamine iv was given, and at the time of insertion of the aspiration cannula into the cervix, another dose of 0.25 mg/kg-1 of ketamine was given iv. The total dose did not exceed 1 mg/kg-1 iv. All patients also received a ketamine-benzodiazepine combination of analgesia prior to the miniabortion procedure. In psychic, unstable women anxiolytic effects were apparent, but in all of them vertigo and the sensation of floating ensued with horizontal and vertical nystagmus, although information could be extracted from them depending on the degree of analgesia. Anterograde amnesia followed, and the systolic and diastolic pressure increased. The maximum duration of analgesic effect was 3-5 minutes, most women became well-oriented without ataxia and returned home 4 hours after the operation. No psychic effects lasted, and nausea or vomiting was minimal. The hallucinogenic effect of ketamine was attributable to the stimulation of the central dopaminergic system, while diazepam (Spofa) influenced the limbic system causing anterograde amnesia. The potential of midazolam-benzodiazepine combination for future sue lies in its very short biological half-life (1.5-2.5 hours) compared with diazepam (24-36 hours).
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PMID:[Analgesia-sedation using ketamine and benzodiazepines in mini-abortion]. 271 9

A 54-year-old, right-handed male suffered sudden onset of vertigo and vomiting. He was diagnosed with brainstem hemorrhage, and treatment was administered. After the vertigo improved, he showed disturbance of attention and anterograde amnesia. Magnetic resonance imaging revealed a hematoma across the pons on both sides, but no lesions were obvious in the cerebellum or the cerebrum. Single photon emission tomography showed decreased perfusion not only in the brainstem but also in the bilateral frontal and temporal lobes. Amnesia and executive dysfunction decreased in the 8 months following the stroke onset, with improvement in regional cerebral blood flow to the frontal and temporal lobes. These findings suggest that a hemorrhage in the pons caused diaschisis resulting in a secondary reduction of activity in the cerebral cortex and the occurrence of cortical symptoms.
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PMID:Cognitive dysfunction in a patient with brainstem hemorrhage. 2022 78