Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042571 (vertigo)
 7,148 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Two cases are presented of sudden deafness with vertigo and/or dizziness, a 19-year-old male and a 54-year-old female. Their onset condition was considered to be caused by vascular disorders in the area of the vertebrobasilar artery, but they showed no signs of the central nervous system disorders. Case 1 suffered right sudden deafness just after a super selective embolization for the peripheral area of the right vertebral artery, and case 2, just after the accidental cutting of the left vertebral artery during the procedure of neurovascular decompression surgery. The neurotologic findings in these cases were almost the same and the common characteristics were (1) irreversible total deafness of the affected ear, (2) canal paresis in caloric test, (3) retrolabyrinthine disorder of the vestibular system detected by the galvanic test, and (4) no obvious findings of central nervous system disorders, such as eye movement disorder or ataxy. These findings indicate that the sudden deafness was attributable to localized embolism in the inner ear artery caused by thrombosis in the area of the vertebrobasilar artery.
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PMID:Sudden deafness from vertebrobasilar artery disorder. 857 54

Neuro-otologic examination is very important in evaluation of balance system. Multiple sclerosis (MS) is the most common chronic, debilitating disease characterized by focal demyelinization that develop throughout of the central nerves system at varying time. Patients with MS presented various complaints and signs, so the aim of the study was the neuro-otologic presentation of multiple findings in patients with MS and comparison with reviewing literature. The study was carried out in 32 patients with MS (21 with relapsing-remitting, 9 with secondary progressive, 1 with primary progressive and 1 with progressive/relapsing types) the mean age was 38 +/- 10 years. Clinical neuro-otologic examinations were performed in all patients paying special attention to eye movement ability. Vertigo as the first symptom was found in 18.8% of patients but up to 68% of patients would complain this symptom at some point of disease. The hearing impairment and tinnitus complains 6.2% patients, optic neuritis 28% patients and double vision 46.9% of them. A few types of eye movement disorder like abnormalities of fixation, gaze-evoked nystagmus, acquired pendular nystagmus and vertical nystagmus in 46.8% patients were observed. The clinical signs of internuclear ophthalmoplegia were noticed in 2 patients. Disturbance in voluntary gaze either in smooth pursuit test (31.3%) and in saccadic test (43.8%) were seen. The multifocal nature of MS explain why this disease are so commonly subject to defect different part of nerve system. Careful neuro-otologic assessment of every patient with MS is necessary to confirm and monitoring the course of disease.
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PMID:[Neuro-otologic findings in multiple sclerosis]. 1635 94