Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042510 (ventricular fibrillation)
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Human Gene/Protein
DPP6 protein 10.6
cardiac sodium channel alpha subunit 10.0
alpha-1B adrenergic receptor 8.8
SCN5A 8.6
CXADR 8.6
LQT5 8.6
Bst1 8.5
KCR1 8.5
MysB 8.5
MiRP1 8.2
KCNK17 8.2
HPF4 8.2
SCN3B 8.1
KCNH2 8.0
Plakophilin-2 7.9
V1-3 7.9
CPR 7.8
CACNA2D1 7.8
SLC4A3 7.7
TALK-2 7.6
LQT1 7.2
HERG 7.2
KCNE2 7.1
KCND3 7.1
SLACK 7.1
TNNC1 7.1
DPP6 7.0
CCPG1 7.0
CACNB2 7.0
LAD 6.7
RYR2 6.7
HAST 6.7
Clerc 6.7
Aminopeptidase P 6.6
V1-2 6.6
CALL 6.5
KvLQT1 6.5
inward rectifier potassium channel 6.5
ATP synthase subunit 6 6.5
CASQ2 6.5
ms2 6.4
SP-22 6.3
SCN1B 6.3
HEY2 6.2
KCNQ1 6.2
UAP 6.1
IK1 6.1
GLI3 6.1
CACNA1C 6.1
Na+ channel protein 6.0
PRKAG2 6.0
gamma-butyrobetaine hydroxylase 6.0
granule membrane protein 140 6.0
C3a anaphylatoxin 6.0
preproET-1 5.9
SECT 5.9
Kir2.1 5.9
KChIP2 5.9
Nav1.5 5.9
tec 5.8
long chain acyl-CoA dehydrogenase 5.8
DIS3 5.8
CPI 5.8
BLS 5.8
VLCAD 5.8
sodium/hydrogen exchanger 5.8
SOD2 protein 5.7
sodium channel 5.7
DSC2 5.7
HLA-DRB1* 5.7
human ether-a-go-go related gene 5.7
CA6 5.6
KCNE1 5.6
MAPA 5.6
CA8 5.6
ICD 5.5
CPK 5.5
Kir2.2 5.5
RyR2 5.4
PCD 5.4
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Disease
PVCs, multifocal 11.6
Cardiocutaneous syndrome 11.6
Pulseless ventricular tachycardia 11.6
Helicoidal ventricular tachycardia 11.6
ventricular fibrillation 11.6
Secondary dilated cardiomyopathy 11.6
Rapid atrial fibrillation 11.6
Primary familial cardiomyopathy 10.6
hypertrichotic osteochondrodysplasia 10.6
Sinus node fibrosis 10.6
Polymorphic ventricular tachycardia 10.1
Sustained ventricular tachycardia 10.1
Atrial fibrillation with rapid ventricular response 10.0
INVM 10.0
Acute transmural myocardial infarction 9.6
Brugada syndrome 9.6
LQT6 9.5
Paroxysmal ventricular tachycardia 9.3
Toxic myocarditis 9.3
Intraventricular block 9.3
SQT3 9.2
Thyrotoxicosis factitia 9.0
Monomorphic ventricular tachycardia 9.0
Accelerated idioventricular rhythm 8.9
Non-sustained ventricular tachycardia 8.8
SQT1 8.8
Acute coronary insufficiency 8.8
pyohydronephrosis 8.8
Left anterior hemiblock 8.8
Radiocontrast nephropathy 8.8
LQT7 8.6
SQT2 8.6
Single vessel disease 8.6
LQT5 8.6
Coronary artery anomaly 8.5
Intraventricular conduction delay 8.5
Chronic hypokalemia 8.5
torsades de pointes 8.4
emotional outburst 8.3
Cocaine intoxication 8.3
Catecholaminergic polymorphic ventricular tachycardia 8.1
long QT syndrome 8.0
coronary occlusion 8.0
LQT3 7.9
Subendocardial ischemia 7.9
preexcitation syndrome 7.9
LQT2 7.8
Wolff-Parkinson-White syndrome 7.8
bradyarrhythmia 7.8
anterolateral myocardial infarction 7.8
LQT1 7.7
ACLS 7.7
Prinzmetal 7.7
SA block 7.6
coronary artery spasm 7.6
vasospastic angina 7.5
sinus tachycardia 7.5
right bundle branch block 7.4
multifocal atrial tachycardia 7.4
flutter 7.4
Febrile illness 7.3
Acute myocardial ischemia 7.3
arthritis of the shoulder 7.2
polyarthrosis 7.2
ARVD 7.2
anterior myocardial infarction 7.2
supraventricular tachycardia 7.2
Waldenstrom's disease 7.2
Jervell and Lange-Nielsen syndrome 7.2
myocardial hypoxia 7.1
Mobitz type II atrioventricular block 7.1
Primary HIV infection 7.1
acute alcoholism 7.1
Stunned myocardium 7.0
Adams-Stokes 7.0
atrioventricular block 7.0
Transient myocardial ischemia 7.0
first degree atrioventricular block 7.0
pentalogy of Fallot 6.9
Myocardial necrosis 6.8
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Symptom
Coronary spastic angina 11.6
Diffuse spasm 9.6
Induced hypothermia 8.2
trigeminy 8.0
bigeminal 7.4
syncope 7.3
Kussmaul's sign 7.2
syncopal episodes 7.2
presyncope 6.8
carpopedal spasm 6.1
cardialgia 5.9
Beau's lines 5.9
hypothermia 5.8
Gasping 5.7
atypical chest pain 5.5
spasm 5.4
exertional chest pain 5.3
Excitable 5.2
chest pain 5.1
asynergy 5.1
angina 5.0
bradypnea 5.0
rales 4.9
cardiovascular impairment 4.9
No pain 4.9
lightheadedness 4.6
sinus pressure 4.6
Anoxia 4.5
Severe pain 4.3
Excitability 4.3
precordial pain 4.2
Regurgitation 4.1
collapse 4.1
exertional angina 4.1
giddiness 4.0
giddiness 4.0
abnormal breathing 3.9
tonic-clonic seizure 3.6
body pain 3.6
consciousness disturbance 3.5
dizziness 3.5
lassitude 3.5
Physical findings 3.2
leg edema 3.2
intention tremor 3.2
chronic back pain 3.1
dyspnea 2.9
anesthesia 2.9
regurgitation 2.8
orthopnea 2.8
neurological disability 2.8
hypercapnia 2.8
cyanosis 2.7
functional recovery 2.7
rundown 2.7
asthenia 2.6
muscle rigidity 2.6
breath holding 2.5
hypocapnia 2.5
persistent cough 2.4
shortness of breath 2.3
drooling 2.2
CSR 2.2
nausea 2.1
chest tightness 2.0
hemiplegia 2.0
lethargy 2.0
tachypnea 1.9
exertional dyspnea 1.9
muscle cramps 1.8
flushing 1.8
blurred vision 1.6
seizures 1.6
fever of unknown origin 1.6
cough 1.5
discomfort 1.5
stridor 1.4
discomfort 1.4
vomiting 1.4
respiratory distress 1.4
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Drug
Encainide hydrochloride 11.6
Ornid 10.3
Nifekalant hydrochloride 10.2
Selectol 9.8
Transcainide 9.3
Conray 400 9.3
Quinidine sulfate 9.2
Aprindine 9.0
Tedisamil 9.0
Bethanidine 9.0
Apstatin 8.8
Cocarboxylase 8.8
Trimepranol 8.7
Deslanoside 8.6
Bidisomide 8.6
CPR 8.4
Ibutilide 8.3
Ioxilan 8.3
Ethmozine 8.2
Ethmozine 8.1
Rotigaptide 8.0
Propulsid 8.0
Iopentol 8.0
Indecainide 7.9
Cicletanine 7.8
Tolamolol 7.8
Carperitide 7.7
Flecainide acetate 7.7
Surfacten 7.6
Flecainide acetate 7.6
Pronestyl 7.5
Redux 7.5
Mifepriston 7.3
Oxfenicine 7.2
SUN 1165 7.2
Pentolinium 7.2
Flolan 7.2
Cordarone 7.0
Flolan 7.0
C4H10 7.0
Alupent 7.0
Acrivastine 6.9
Ergometrine 6.8
Dronedarone 6.8
Alupent 6.7
Prenylamine 6.7
Cordarone 6.7
Arfonad 6.7
Lubeluzole 6.6
Procaine hydrochloride 6.6
K201 6.6
Nadolol 6.6
Anexate 6.5
Diprolene 6.5
Ranolazine 6.5
Ranolazine 6.5
Dopexamine hydrochloride 6.5
Magnesium sulfate 6.4
LCBF 6.4
Molsidomine 6.4
Quinate 6.3
Doxifluridine 6.3
APD 6.3
Dazmegrel 6.3
Metoprolol tartrate 6.3
Alprenolol 6.3
Lidoflazine 6.2
Lugol's solution 6.2
Iomeprol 6.2
Visken 6.2
Omacor 6.1
Arfonad 6.1
Dormicum 6.0
Hydroxyethylstarch 5.9
Potassium citrate 5.9
Innovar 5.9
Nisoxetine 5.8
Dantrolene sodium 5.8
Iodixanol 5.8
Iohexol 5.8
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Enzyme
CPR 6.7
LMT 6.4
gamma-butyrobetaine hydroxylase 5.3
alliinase 4.7
creatine kinase 4.5
CCS 4.4
CAO 4.2
aminopeptidase P 3.9
CPN 3.9
FFT 3.8
ancrod 3.8
lysophosphatidylcholine acyltransferase 3.6
biliverdin reductase 3.5
thromboxane synthase 3.5
LIS 3.4
Alternating 3.3
propionyl-CoA carboxylase 3.2
propionyl-CoA carboxylase 3.2
Lys4 3.2
ACAT 3.1
SST 3.1
SCP 2.8
ACE 2.8
BIS 2.7
SPT 2.6
p80 2.5
lactate dehydrogenase 2.4
xanthine oxidase 2.3
tissue plasminogen activator 2.2
MDH 2.0
dihydropyrimidine dehydrogenase 2.0
SPS 2.0
MAP 1.9
PST 1.9
MDH 1.9
pyruvate dehydrogenase 1.9
succinic dehydrogenase 1.9
pyruvate dehydrogenase 1.9
SPT 1.8
IMP dehydrogenase 1.8
phosphorylase 1.8
diacylglycerol kinase 1.7
angiotensin-converting enzyme 2 1.6
adenosine deaminase 1.6
nucleotidase 1.6
cholesterol acyltransferase 1.6
adenosine deaminase 1.6
lysin 1.6
heme oxygenase 1.6
pyruvate dehydrogenase 1.5
phosphodiesterase 1.5
renin 1.5
lecithin:cholesterol acyltransferase 1.4
uricase 1.4
dihydropyrimidine dehydrogenase 1.4
superoxide dismutase 1.3
tissue kallikrein 1.3
diaphorase 1.2
aequorin 1.1
histidine decarboxylase 1.1
NO synthase 1.0
alpha-galactosidase 0.9
paraoxonase 0.9
AOR 0.8
ATPase 0.8
urokinase-type plasminogen activator 0.8
catalase 0.8
MPP 0.8
NADPH-diaphorase 0.7
paraoxonase 0.6
adenylate cyclase 0.6
CAD 0.5
CAD 0.5
soluble epoxide hydrolase 0.5
ADH 0.5
PDK1 0.5
CAD 0.5
alcohol dehydrogenase 0.4
N-acetyltransferase 0.4
aspartate aminotransferase 0.4
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Compound
Hoe 933 11.6
1,1-diphenyl-1-butanol 10.6
C3F7I 10.6
Bretylium tosylate 10.3
Chimyl alcohol 10.0
2,4,6-T 9.6
Sophoramine 9.6
Bretylium 9.5
Lorcainide hydrochloride 9.3
Quinidine sulfate 9.0
Regulin 8.9
Moricizine 8.7
Azimilide 8.5
Ibutilide 8.4
Corynanthine 8.3
Tiapamil 8.1
Disopyramide phosphate 8.0
Clofilium 8.0
Mexiletine 7.9
Amiodarone 7.8
Flecainide 7.7
2,3-naphthalenediol 7.7
Sotalol 7.7
Disopyramide 7.7
Encainide 7.6
Dofetilide 7.6
N-Acetylmethionine 7.5
Amiodarone hydrochloride 7.5
CE 2 7.5
Ergonovine 7.4
Procainamide 7.4
Aconitine 7.3
Aconitine 7.3
Quinidine 7.3
Propafenone 7.2
Berbamine 7.1
3-hydroxyquinidine 7.1
NFN 7.1
Etanidazole 7.1
Gallopamil 7.1
Cetiedil 6.9
E-4031 6.9
Lanatoside C 6.9
Dauricine 6.9
Lidocaine 6.8
Sooner 6.8
1H-indole-3-carboxylic acid 6.8
Sulfinpyrazone 6.8
Anexate 6.8
Bepridil 6.7
Syringin 6.7
Practolol 6.7
Cromakalim 6.6
Ajmaline 6.6
N-hydroxyguanidine 6.6
Pinacidil 6.6
Hearts 6.5
Protriptyline 6.5
Metaraminol 6.5
Dothiepin 6.5
Stearidonic acid 6.5
Metipranolol 6.5
Azaperone 6.3
Dormicum 6.3
Magnesium sulfate 6.3
Methylxanthine 6.3
X 21 6.2
Magnesium sulfate 6.2
Glibenclamide 6.2
propionyl-carnitine 6.2
Tocainide 6.1
Levobupivacaine 6.1
Dantrolene sodium 6.1
decahydroquinoline 6.0
PKF 6.0
Glimepiride 6.0
Danshensu 5.9
4-phenyl-3-buten-2-one 5.9
4-phenyl-3-buten-2-one 5.9
Moxonidine 5.9
more...