Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042384 (
vasculitis
)
20,525
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Paroxetine (
Paxil
) is a widely prescribed antidepressant of the selective serotonin reuptake inhibitor (SSRI) class for which multiple cutaneous adverse effects have been reported, including urticaria, ecchymoses,
vasculitis
, and pruritus. In contrast, fluoxetine (Prozac) is the only SSRI previously reported to cause urticarial
vasculitis
. Urticarial vasculitis is a chronic disorder marked by recurrent episodes of erythematous, indurated wheals that histologically manifest the features of leukocytoclastic
vasculitis
. This case represents the first reported incidence of paroxetine-induced urticarial
vasculitis
, and highlights the need to consider the entire SSRI class as s as a potential cause of the condition.
...
PMID:Urticarial vasculitis secondary to paroxetine. 1737 54
