Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042384 (
vasculitis
)
20,525
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Drug-induced leukocytoclastic
vasculitis
is a small-vessel
vasculitis
that most commonly manifests with palpable purpuric lesions on gravity-dependent areas.
Vasculitis
occurs within weeks after initial administration of medication and demonstrates clearance upon withdrawal of medication.
Levetiracetam
, a pyrrolidone derivative, is used as an adjunctive therapy in patients with refractory focal epilepsy, myoclonic epilepsy, and primary generalized tonic-clonic seizures. We present a case of a 14-year-old female, who developed cutaneous small-vessel
vasculitis
within 8 days of initiation of levetiracetam.
Vasculitis
was successfully managed by discontinuation of medication and systemic corticosteroids. This adverse reaction, to the best of our knowledge, has not been previously reported in literature.
...
PMID:Levetiracetam-induced leukocytoclastic vasculitis. 2845 37
