Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042373 (
vascular disease
)
17,070
document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds)
.
Concepts found in the documents ranked by [
Frequency
|
Pointwise Mutual Information
|
Symmetric Conditional Probability
] .
Human Gene/Protein
Sep
1089
insulin
870
collagen
825
Mol
441
MRI
327
amyloid precursor protein
324
HDL
250
fibrinogen
228
apolipoprotein E
196
angiotensin II
188
cytokine
188
renin
187
cystatin C
184
C-reactive protein
176
nitric oxide synthase
164
vascular endothelium
163
albumin
160
amyloid beta
160
thrombin
147
hemoglobin
145
She
144
vascular endothelial growth factor
138
B12
124
endothelin-1
98
Ang II
97
von Willebrand factor
97
elastin
92
apolipoprotein
90
endothelial nitric oxide synthase
88
methylenetetrahydrofolate reductase
85
chronic renal failure
82
tumor necrosis factor
82
APOE
80
plasminogen activator inhibitor-1
79
Lp(a)
75
TNF
74
APP
74
apoE
73
ADP
71
IL-6
71
superoxide dismutase
70
calcium channel
69
vascular cell adhesion molecule-1
66
phosphodiesterase
66
PLA
65
Mal
65
VEGF
64
endoglin
62
glycoprotein
61
adiponectin
61
fibronectin
60
ACE
60
p38
59
eNOS
59
plasminogen
59
ATP
59
tissue factor
56
reductase
55
endoplasmic reticulum
53
plasminogen activator inhibitor
52
axonal
51
interleukin-6
51
matrix metalloproteinase
50
prothrombin
50
LDL receptor
50
CSF
50
CADASIL
49
platelet-derived growth factor
49
bradykinin
49
CD105
48
apolipoprotein B
47
protein C
46
serum albumin
46
antithrombin III
45
MAPK
44
Pol
43
cystathionine beta-synthase
43
E-selectin
43
catalase
43
ERK1
42
more...
Disease
vascular disease
17070
diabetes
2541
hypertension
2421
atherosclerosis
2079
stroke
1666
Alzheimer's disease
1496
cardiovascular disease
1227
dementia
904
myocardial infarction
647
coronary artery disease
612
plaque
601
pulmonary hypertension
555
cancer
524
ischemia
523
obesity
518
renal disease
496
type 2 diabetes
459
cognitive impairment
395
heart failure
369
coronary heart disease
365
vasculitis
312
hyperglycemia
298
heart disease
297
hyperhomocysteinemia
292
hyperlipidemia
280
peripheral vascular disease
263
myocardial ischemia
258
tumor
248
renal failure
243
neuropathy
242
systemic lupus erythematosus
233
hypercholesterolemia
233
retinopathy
232
amyloidosis
218
dyslipidemia
210
metabolic syndrome
209
arteriosclerosis
182
congestive heart failure
180
depression
169
transient ischemic attack
163
erectile dysfunction
147
diabetic retinopathy
145
PSS
144
abdominal aortic aneurysm
141
arteriopathy
139
CAA
138
Endothelial dysfunction
136
lung disease
124
rheumatoid arthritis
122
proteinuria
122
chronic renal failure
120
encephalopathy
120
lupus
117
leukoencephalopathy
116
subarachnoid hemorrhage
115
migraine
115
type 1 diabetes
110
ventricular hypertrophy
108
claudication
105
dysplasia
101
sepsis
101
HIV
100
Down syndrome
99
preeclampsia
99
cerebral ischemia
98
Parkinson's disease
98
anemia
97
cerebral infarction
95
lupus
94
HHT
93
sepsis
93
cardiomyopathy
93
scleroderma
93
microalbuminuria
93
moyamoya
92
acute myocardial infarction
91
osteoporosis
89
telangiectasia
89
interstitial pneumonia
89
blindness
89
more...
Symptom
pain
268
headache
176
seizures
143
angina
121
dyspnea
82
anesthesia
79
weakness
63
overweight
57
abdominal pain
56
diarrhea
36
vertigo
33
vomiting
33
cough
32
ataxia
31
chest pain
31
dizziness
29
fatigue
29
paresthesia
27
syncope
27
cyanosis
24
spasm
23
discomfort
22
hypothermia
22
paresis
22
discomfort
22
dysarthria
21
collapse
21
hemiplegia
21
tremor
21
numbness
20
erythema
20
livedo
19
thinning
18
myoclonus
18
respiratory distress
18
back pain
18
memory loss
16
nausea
16
pallor
16
myalgia
16
tinnitus
15
hypercapnia
14
sleepiness
14
exertional dyspnea
14
hemoptysis
13
cerebellar ataxia
13
paraparesis
12
arthralgia
12
fever of unknown origin
12
ophthalmoplegia
11
snoring
11
hyperoxia
11
functional recovery
11
analgesia
11
muscle cramps
11
flushing
11
splenomegaly
9
anorexia
9
agitation
9
lethargy
9
regurgitation
9
chorea
8
leg pain
8
insomnia
7
starvation
7
blurred vision
7
cachexia
7
neck pain
6
oliguria
6
loin pain
6
spasticity
6
tonic-clonic seizure
6
dystonia
6
HSA
6
bradykinesia
6
shortness of breath
6
chills
5
epigastric pain
5
wheezing
5
consciousness disturbance
5
more...
Drug
Cardiovasc
562
Dermatol
91
vitamin E
57
CSF
52
Dial
51
lysine
40
Angiotensin II
38
Gliclazide
36
Perindopril
36
ROS
32
ascorbate
28
Nephron
25
Clopidogrel
24
Monit
24
pyridoxal phosphate
21
nitroglycerin
20
Nephron
20
Spectrum
18
THF
18
Pravastatin
17
BH4
16
niacin
14
NADH
13
Simvastatin
13
Fluorescein
12
Vitamin B12
12
Nitric Oxide
11
Fluorescein
11
CTA
11
Heme
11
Albumin
10
Estrogens
10
caffeine
10
Vitamin K
10
MAP
10
Ramipril
9
ADM
8
Captopril
8
Vitamin E
8
ROC
8
IFN-gamma
8
EE2
8
Vitamin B
8
Asn
7
ICI
7
Norplant
6
CTX
6
uPA
6
Ezetimibe
6
ETA
6
ENT
6
Leaf
6
Bevacizumab
6
ABC
6
Rosuvastatin
6
Histamine
6
EPA
6
Abciximab
5
FAD
5
Arsenic trioxide
5
Cilostazol
5
Trental
5
MRC
5
Portal
5
Ranibizumab
5
IL-2
5
Xanthium
5
CVA
5
Iloprost
4
TAT
4
Troglitazone
4
Lovastatin
4
Frontal
4
CaCl2
4
Paraffin
4
Imatinib
3
ampicillin
3
Levonorgestrel
3
Glutathione
3
Aliskiren
3
more...
Enzyme
renin
187
mitogen-activated protein kinase
156
thrombin
144
ACE
109
NO synthase
103
NADPH oxidase
99
methylenetetrahydrofolate reductase
92
methylenetetrahydrofolate reductase
92
superoxide dismutase
85
protein kinase C
85
tissue plasminogen activator
76
ERK
71
NADPH oxidase
71
phosphodiesterase
66
protein kinase
64
APC
57
peroxidase
54
catalase
48
cystathionine beta-synthase
43
luciferase
38
NOS
37
focal adhesion kinase
36
plasmin
34
elastase
34
lipoprotein lipase
33
caspase-3
33
guanylate cyclase
29
glutathione peroxidase
27
thromboplastin
26
xanthine oxidase
26
paraoxonase
23
paraoxonase
22
phospholipase A2
22
CD10
21
acetylcholinesterase
21
alkaline phosphatase
21
MEK
20
ATPase
20
urokinase-type plasminogen activator
19
CAD
19
CAD
19
CAD
19
phosphatidylinositol 3-kinase
19
calcineurin
19
AMP-activated protein kinase
18
methionine synthase
16
arginase
16
kallikrein
15
methionine synthase
15
creatine kinase
15
heme oxygenase
15
collagenase
14
cholinesterase
13
proteasome
13
PAH
13
PKG
13
beta-galactosidase
13
alanine aminotransferase
12
aldose reductase
12
lipoxygenase
11
lipase
11
phospholipase C
11
IKK
10
lactate dehydrogenase
10
ACS
10
reverse transcriptase
10
neutrophil elastase
10
P-glycoprotein
9
AMPK
9
aspartate aminotransferase
8
MAP
8
phosphoinositide 3-kinase
8
MMP
8
PDE
8
PTA
8
3-hydroxy-3-methylglutaryl coenzyme A reductase
8
chymase
8
trypsin
8
RNase
8
alpha-galactosidase
8
more...
Compound
Clin
1428
Dec
1172
glucose
728
oxygen
690
homocysteine
618
Cardiol
581
nitric oxide
559
DNA
362
calcium
333
methionine
193
creatinine
182
sodium
171
prostacyclin
162
arginine
156
water
153
Homocysteine
136
Homocysteine
136
phosphate
123
acetate
109
cysteine
105
ASA
103
ADP
102
Insulin
102
hydrogen
85
iron
75
CO2
75
aldosterone
74
TNF
74
ADP
71
ADP
71
salt
65
sulfate
65
Ang II
64
Angiotensin II
62
Cholesterol
59
ATP
59
potassium
59
serine
59
tyrosine
58
nitrogen
57
CAA
55
cGMP
55
zinc
53
lysine
52
Cereb
51
Dial
51
Retinal
50
Congo red
50
PGA
48
His
42
copper
42
urea
40
silver
39
Collagen
37
ethanol
34
NADPH
34
threonine
34
NADPH
34
vitamin D
33
nitrate
30
adenosylmethionine
29
S-adenosylhomocysteine
29
leucine
28
glutamate
28
H2O2
28
GSH
27
AMP
27
GSH
27
alanine
27
Estrogen
26
Diabetol
26
NAD
25
THP
25
THP
25
ACh
25
nicotinamide
25
glutamine
24
galactose
24
prostaglandin E1
23
GMP
23
more...