Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042373 (vascular disease)
17,070 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
Sep 1089
insulin 870
collagen 825
Mol 441
MRI 327
amyloid precursor protein 324
HDL 250
fibrinogen 228
apolipoprotein E 196
angiotensin II 188
cytokine 188
renin 187
cystatin C 184
C-reactive protein 176
nitric oxide synthase 164
vascular endothelium 163
albumin 160
amyloid beta 160
thrombin 147
hemoglobin 145
She 144
vascular endothelial growth factor 138
B12 124
endothelin-1 98
Ang II 97
von Willebrand factor 97
elastin 92
apolipoprotein 90
endothelial nitric oxide synthase 88
methylenetetrahydrofolate reductase 85
chronic renal failure 82
tumor necrosis factor 82
APOE 80
plasminogen activator inhibitor-1 79
Lp(a) 75
TNF 74
APP 74
apoE 73
ADP 71
IL-6 71
superoxide dismutase 70
calcium channel 69
vascular cell adhesion molecule-1 66
phosphodiesterase 66
PLA 65
Mal 65
VEGF 64
endoglin 62
glycoprotein 61
adiponectin 61
fibronectin 60
ACE 60
p38 59
eNOS 59
plasminogen 59
ATP 59
tissue factor 56
reductase 55
endoplasmic reticulum 53
plasminogen activator inhibitor 52
axonal 51
interleukin-6 51
matrix metalloproteinase 50
prothrombin 50
LDL receptor 50
CSF 50
CADASIL 49
platelet-derived growth factor 49
bradykinin 49
CD105 48
apolipoprotein B 47
protein C 46
serum albumin 46
antithrombin III 45
MAPK 44
Pol 43
cystathionine beta-synthase 43
E-selectin 43
catalase 43
ERK1 42
more...
Disease
vascular disease 17070
diabetes 2541
hypertension 2421
atherosclerosis 2079
stroke 1666
Alzheimer's disease 1496
cardiovascular disease 1227
dementia 904
myocardial infarction 647
coronary artery disease 612
plaque 601
pulmonary hypertension 555
cancer 524
ischemia 523
obesity 518
renal disease 496
type 2 diabetes 459
cognitive impairment 395
heart failure 369
coronary heart disease 365
vasculitis 312
hyperglycemia 298
heart disease 297
hyperhomocysteinemia 292
hyperlipidemia 280
peripheral vascular disease 263
myocardial ischemia 258
tumor 248
renal failure 243
neuropathy 242
systemic lupus erythematosus 233
hypercholesterolemia 233
retinopathy 232
amyloidosis 218
dyslipidemia 210
metabolic syndrome 209
arteriosclerosis 182
congestive heart failure 180
depression 169
transient ischemic attack 163
erectile dysfunction 147
diabetic retinopathy 145
PSS 144
abdominal aortic aneurysm 141
arteriopathy 139
CAA 138
Endothelial dysfunction 136
lung disease 124
rheumatoid arthritis 122
proteinuria 122
chronic renal failure 120
encephalopathy 120
lupus 117
leukoencephalopathy 116
subarachnoid hemorrhage 115
migraine 115
type 1 diabetes 110
ventricular hypertrophy 108
claudication 105
dysplasia 101
sepsis 101
HIV 100
Down syndrome 99
preeclampsia 99
cerebral ischemia 98
Parkinson's disease 98
anemia 97
cerebral infarction 95
lupus 94
HHT 93
sepsis 93
cardiomyopathy 93
scleroderma 93
microalbuminuria 93
moyamoya 92
acute myocardial infarction 91
osteoporosis 89
telangiectasia 89
interstitial pneumonia 89
blindness 89
more...
Symptom
pain 268
headache 176
seizures 143
angina 121
dyspnea 82
anesthesia 79
weakness 63
overweight 57
abdominal pain 56
diarrhea 36
vertigo 33
vomiting 33
cough 32
ataxia 31
chest pain 31
dizziness 29
fatigue 29
paresthesia 27
syncope 27
cyanosis 24
spasm 23
discomfort 22
hypothermia 22
paresis 22
discomfort 22
dysarthria 21
collapse 21
hemiplegia 21
tremor 21
numbness 20
erythema 20
livedo 19
thinning 18
myoclonus 18
respiratory distress 18
back pain 18
memory loss 16
nausea 16
pallor 16
myalgia 16
tinnitus 15
hypercapnia 14
sleepiness 14
exertional dyspnea 14
hemoptysis 13
cerebellar ataxia 13
paraparesis 12
arthralgia 12
fever of unknown origin 12
ophthalmoplegia 11
snoring 11
hyperoxia 11
functional recovery 11
analgesia 11
muscle cramps 11
flushing 11
splenomegaly 9
anorexia 9
agitation 9
lethargy 9
regurgitation 9
chorea 8
leg pain 8
insomnia 7
starvation 7
blurred vision 7
cachexia 7
neck pain 6
oliguria 6
loin pain 6
spasticity 6
tonic-clonic seizure 6
dystonia 6
HSA 6
bradykinesia 6
shortness of breath 6
chills 5
epigastric pain 5
wheezing 5
consciousness disturbance 5
more...
Drug
Cardiovasc 562
Dermatol 91
vitamin E 57
CSF 52
Dial 51
lysine 40
Angiotensin II 38
Gliclazide 36
Perindopril 36
ROS 32
ascorbate 28
Nephron 25
Clopidogrel 24
Monit 24
pyridoxal phosphate 21
nitroglycerin 20
Nephron 20
Spectrum 18
THF 18
Pravastatin 17
BH4 16
niacin 14
NADH 13
Simvastatin 13
Fluorescein 12
Vitamin B12 12
Nitric Oxide 11
Fluorescein 11
CTA 11
Heme 11
Albumin 10
Estrogens 10
caffeine 10
Vitamin K 10
MAP 10
Ramipril 9
ADM 8
Captopril 8
Vitamin E 8
ROC 8
IFN-gamma 8
EE2 8
Vitamin B 8
Asn 7
ICI 7
Norplant 6
CTX 6
uPA 6
Ezetimibe 6
ETA 6
ENT 6
Leaf 6
Bevacizumab 6
ABC 6
Rosuvastatin 6
Histamine 6
EPA 6
Abciximab 5
FAD 5
Arsenic trioxide 5
Cilostazol 5
Trental 5
MRC 5
Portal 5
Ranibizumab 5
IL-2 5
Xanthium 5
CVA 5
Iloprost 4
TAT 4
Troglitazone 4
Lovastatin 4
Frontal 4
CaCl2 4
Paraffin 4
Imatinib 3
ampicillin 3
Levonorgestrel 3
Glutathione 3
Aliskiren 3
more...
Enzyme
renin 187
mitogen-activated protein kinase 156
thrombin 144
ACE 109
NO synthase 103
NADPH oxidase 99
methylenetetrahydrofolate reductase 92
methylenetetrahydrofolate reductase 92
superoxide dismutase 85
protein kinase C 85
tissue plasminogen activator 76
ERK 71
NADPH oxidase 71
phosphodiesterase 66
protein kinase 64
APC 57
peroxidase 54
catalase 48
cystathionine beta-synthase 43
luciferase 38
NOS 37
focal adhesion kinase 36
plasmin 34
elastase 34
lipoprotein lipase 33
caspase-3 33
guanylate cyclase 29
glutathione peroxidase 27
thromboplastin 26
xanthine oxidase 26
paraoxonase 23
paraoxonase 22
phospholipase A2 22
CD10 21
acetylcholinesterase 21
alkaline phosphatase 21
MEK 20
ATPase 20
urokinase-type plasminogen activator 19
CAD 19
CAD 19
CAD 19
phosphatidylinositol 3-kinase 19
calcineurin 19
AMP-activated protein kinase 18
methionine synthase 16
arginase 16
kallikrein 15
methionine synthase 15
creatine kinase 15
heme oxygenase 15
collagenase 14
cholinesterase 13
proteasome 13
PAH 13
PKG 13
beta-galactosidase 13
alanine aminotransferase 12
aldose reductase 12
lipoxygenase 11
lipase 11
phospholipase C 11
IKK 10
lactate dehydrogenase 10
ACS 10
reverse transcriptase 10
neutrophil elastase 10
P-glycoprotein 9
AMPK 9
aspartate aminotransferase 8
MAP 8
phosphoinositide 3-kinase 8
MMP 8
PDE 8
PTA 8
3-hydroxy-3-methylglutaryl coenzyme A reductase 8
chymase 8
trypsin 8
RNase 8
alpha-galactosidase 8
more...
Compound
Clin 1428
Dec 1172
glucose 728
oxygen 690
homocysteine 618
Cardiol 581
nitric oxide 559
DNA 362
calcium 333
methionine 193
creatinine 182
sodium 171
prostacyclin 162
arginine 156
water 153
Homocysteine 136
Homocysteine 136
phosphate 123
acetate 109
cysteine 105
ASA 103
ADP 102
Insulin 102
hydrogen 85
iron 75
CO2 75
aldosterone 74
TNF 74
ADP 71
ADP 71
salt 65
sulfate 65
Ang II 64
Angiotensin II 62
Cholesterol 59
ATP 59
potassium 59
serine 59
tyrosine 58
nitrogen 57
CAA 55
cGMP 55
zinc 53
lysine 52
Cereb 51
Dial 51
Retinal 50
Congo red 50
PGA 48
His 42
copper 42
urea 40
silver 39
Collagen 37
ethanol 34
NADPH 34
threonine 34
NADPH 34
vitamin D 33
nitrate 30
adenosylmethionine 29
S-adenosylhomocysteine 29
leucine 28
glutamate 28
H2O2 28
GSH 27
AMP 27
GSH 27
alanine 27
Estrogen 26
Diabetol 26
NAD 25
THP 25
THP 25
ACh 25
nicotinamide 25
glutamine 24
galactose 24
prostaglandin E1 23
GMP 23
more...