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Query: UMLS:C0042373 (vascular disease)
 17,070 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

In a review of his experience with thoracic outlet compression, the author attempts to define factors that will help select patients for operation. Fifty-three patients underwent 59 transaxillary resections of the first rib. In almost all cases the diagnosis was clinical, based mainly on the history. Aortography was useful only when intrinsic vascular disease was suspected. Nerve-conduction studies were not helpful and were used only to confirm a diagnosis of peripheral nerve compression. Of 44 patients followed up, 33 had good or excellent results. Of the 11 patients with poor results, 8 complained of persistent neck and shoulder pain. The author concludes that the diagnosis of thoracic outlet compression is clinical and is based mainly on the patient's history. Transaxillary resection is safe and effective, particularly for patients whose symptoms are mainly in the hand and arm. It is not effective for those whose predominant complaint is neck and shoulder pain.
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PMID:Thoracic outlet compression. 646

Necrotizing fasciitis is a rare, aggressive, soft-tissue infection that results in necrosis of skin, subcutaneous tissue, and fascia. It spreads rapidly and may progress to sepsis, multi-organ failure, and death. Predisposing conditions include diabetes, chronic alcoholism, advanced age, vascular disease, and immunosuppression and many cases are preceded by an injury or invasive procedure. Necrotizing soft-tissue infection of the breast is uncommon, with only a few reported cases in the literature. We present a 53-year-old diabetic woman who presented to the emergency room with several weeks of worsening breast and shoulder pain, swelling, and erythema. Upon formal evaluation by the surgical service, a necrotizing soft-tissue infection was suspected, and the patient was scheduled for emergent, surgical debridement. Because of the aggressive nature and high mortality of this disease, immediate surgical intervention, coupled with antibiotic therapy and physiologic support, is necessary to prevent complications and death.
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PMID:Necrotizing Fasciitis of the Breast Requiring Emergent Radical Mastectomy. 2763 8