Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.01 seconds) .

Concepts found in the documents ranked by [ Frequency | Pointwise Mutual Information | Symmetric Conditional Probability ] .
Human Gene/Protein
IgE 1029
Sep 377
mast cell 263
She 159
cytokine 78
NALP3 58
C1 inhibitor 57
scratch 56
AII 47
bradykinin 46
IL-4 41
gut 40
IgA 37
Pol 36
CD4 35
Mol 33
CAP 33
substance P 33
C-reactive protein 33
ASA 28
kallikrein 27
cyclooxygenase 27
IL-5 27
serum albumin 27
IL-1 27
NLRP3 26
collagen 24
interferon 24
insulin 23
tumor necrosis factor 22
por 22
IL-6 20
CIAS1 20
albumin 20
histamine H1 receptor 20
TNF 20
eosinophil cationic protein 19
C1-INH 19
CD8 19
kit 19
COX-2 19
EDF 19
esterase 18
reserved 18
IFN 17
SDS 17
IL-13 16
ACE 15
IL-17 15
COX-1 15
CRP 15
rheumatoid factor 15
peroxidase 15
lymphoid 15
thyroglobulin 14
Pseudomonas 14
alpha-chain 14
HLA 14
IL-10 14
hemoglobin 13
GPT 13
IL-8 12
ICAM-1 12
chemokine 12
olfactory 12
lipopolysaccharide 12
cyclooxygenase-1 11
CD20 11
cytochrome P450 11
JAMA 11
myeloperoxidase 11
superoxide dismutase 10
Mil 10
MRI 10
pyrin 10
SARS 10
thrombin 10
cage 9
fibrinogen 9
IFN-gamma 9
PGD2 9
interferon-gamma 9
IL-31 9
granulocyte 9
thyroid peroxidase 9
IL-2 9
catalase 9
lamp 9
TNF receptor 9
Mal 9
TNF-alpha 9
tyrosine kinase 8
HLA-DR 8
tap 8
P-selectin 8
TPO 8
SPT 8
IgG3 8
CSF 8
tropomyosin 8
protease inhibitor 8
microsomal 8
vascular cell adhesion molecule-1 8
P-glycoprotein 7
San 7
tissue factor 7
E-selectin 7
tumor necrosis factor receptor 7
Hop 7
alkaline phosphatase 7
IL-33 7
PLCG2 7
interferon alpha 7
mucin 7
ESI 7
ferritin 7
vascular endothelial growth factor 7
polypeptide 7
ANA 7
casein 7
diamine oxidase 7
IL-18 7
CD25 7
B10 7
c-kit 7
COX 6
Itch 6
inducible nitric oxide synthase 6
interleukin-6 6
calcium channel 6
proton pump 6
Cytokine 6
PAF 6
MEFV 6
ATP 6
interleukin-2 6
nerve growth factor 6
xenobiotic 6
surface antigen 6
PGD 6
RANTES 6
BP180 6
PPD 6
calcitonin 6
glycoprotein 6
calcineurin 6
ELAM-1 6
cyclooxygenase-2 6
P450 5
castor 5
angiotensin II receptor 5
lymphokine 5
interleukin-4 5
parvalbumin 5
factor VIII 5
mevalonate kinase 5
TCTP 5
epidermal growth factor receptor 5
5-lipoxygenase 5
serum amyloid A 5
more...
Disease
urticaria 6569
asthma 1097
anaphylaxis 748
pruritus 746
chronic urticaria 660
atopic dermatitis 505
rash 395
Contact Dermatitis 391
cold 357
eczema 320
dermatitis 312
rhinitis 308
vasculitis 303
allergic rhinitis 285
food allergy 274
psoriasis 206
skin disease 170
bronchospasm 141
systemic lupus erythematosus 133
cancer 127
erythema multiforme 119
conjunctivitis 119
eosinophilia 101
hay fever 101
purpura 100
lupus 99
arthritis 90
photosensitivity 85
Hereditary angioedema 84
drug hypersensitivity 82
acne 82
mastocytosis 76
depression 69
tumor 67
lupus 61
Stevens-Johnson syndrome 58
serum sickness 58
Muckle-Wells syndrome 57
prurigo 56
autoimmune disease 53
Anisakis 52
infectious diseases 49
vitiligo 49
infestation 47
rheumatoid arthritis 46
lichen planus 45
hepatitis 42
diabetes 41
lymphadenopathy 41
pemphigoid 41
pneumonia 40
systemic disease 40
thrombocytopenia 39
hypertension 38
Acute urticaria 37
rosacea 35
Contact urticaria 34
alopecia areata 33
CAP 33
virus infection 33
respiratory disease 32
scabies 32
Schnitzler syndrome 31
lymphoma 31
erythema nodosum 31
erythroderma 30
Solar urticaria 29
Infection 29
penicillin allergy 29
pemphigus 28
cryoglobulinemia 28
glomerulonephritis 28
immunodeficiency 28
anemia 27
hepatitis B 27
HIV 27
amyloidosis 27
allergic conjunctivitis 27
Hashimoto's thyroiditis 26
deafness 26
Cold urticaria 25
melanoma 25
warts 25
leukemia 25
influenza 25
hepatitis C 25
AIDS 24
seborrheic dermatitis 24
proteinuria 23
neutropenia 23
celiac disease 23
folliculitis 23
fungal infection 23
petechiae 23
dermatitis herpetiformis 23
skin hypersensitivity 22
renal disease 22
erythropoietic protoporphyria 22
familial Mediterranean fever 22
migraine 22
multiple sclerosis 21
herpes simplex 21
cellulitis 21
polyposis 21
Echinococcus 21
sinusitis 20
rare disease 20
porphyria cutanea tarda 20
Graves' disease 20
urticaria pigmentosa 20
Wells 19
bronchitis 19
acne vulgaris 19
Hodgkin's disease 19
allergic urticaria 19
gastritis 19
renal failure 19
irritable bowel syndrome 19
esophagitis 19
hyperthyroidism 19
plaque 18
hidradenitis 18
bacterial infection 18
porphyria 18
Atopic 18
ulcerative colitis 17
autoimmune thyroid disease 17
multiple myeloma 17
malaria 17
West 17
carcinoma 17
SDS 17
Crohn's disease 17
mycosis fungoides 17
enterocolitis 17
Autoimmune progesterone dermatitis 16
polyarthritis 16
stomatitis 16
bronchitis 16
malnutrition 16
Sweet 16
sarcoidosis 16
skin cancer 16
melasma 16
Exercise-induced anaphylaxis 15
liver disease 15
pityriasis rosea 15
Toxic epidermal necrolysis 15
dermographia 15
Chronic idiopathic urticaria 15
Helicobacter pylori infection 15
Allergic contact dermatitis 15
dysphagia 15
ichthyosis 15
herpes 15
ichthyosis 15
pyoderma gangrenosum 15
dermatomyositis 15
Kawasaki disease 15
tetanus 14
more...
Symptom
erythema 275
Welt 212
diarrhea 167
vomiting 163
dyspnea 162
pain 148
nausea 142
headache 133
abdominal pain 115
wheezing 108
arthralgia 107
flushing 89
collapse 88
cough 64
sleepiness 64
anesthesia 61
fatigue 45
dizziness 44
syncope 43
discomfort 40
discomfort 40
respiratory distress 35
chills 34
sneezing 33
chest pain 31
shortness of breath 28
weakness 28
Ill 26
Urticarial vasculitis 26
seizures 26
rhinorrhea 22
myalgia 21
nausea and vomiting 20
nasal congestion 19
livedo 18
constipation 15
bone pain 15
colic 14
stridor 14
anorexia 13
hepatosplenomegaly 13
hoarseness 13
vertigo 13
chest tightness 13
angina 11
paresthesia 11
epigastric pain 11
numbness 10
abdominal cramps 10
splenomegaly 10
dry skin 10
tingling 9
cyanosis 9
spasm 9
agitation 8
analgesia 8
rigors 8
pallor 8
chronic cough 8
skin irritation 8
asthenia 7
lethargy 7
sore throat 7
Scratch 7
periorbital edema 7
Sedation 6
acute abdomen 6
nasal discharge 6
blurred vision 6
hypothermia 5
Food intolerance 5
stomach pain 5
ENT 5
tinnitus 5
tense 4
dystonia 4
low back pain 4
HSA 4
oliguria 4
generalized rash 4
generalized erythema 4
insomnia 4
Skin symptoms 4
tachypnea 4
lightheadedness 4
tremor 4
exhaustion 3
overweight 3
dysuria 3
dysesthesia 3
muscle cramps 3
photophobia 3
stigma 3
throat irritation 3
Generalized urticaria 3
bloating 3
Wind 3
Vibratory angioedema 3
ataxia 3
glossodynia 3
acidity 3
Flare 3
hepatomegaly 3
thinning 3
back pain 3
vaginal itching 2
intestinal bleeding 2
Burning 2
Stinging 2
hypotonia 2
enuresis 2
clubbing 2
presyncope 2
Gastrointestinal symptoms 2
excessive sweating 2
night sweats 2
physical appearance 2
Macula 2
General symptoms 2
polyuria 2
Generalized pruritus 2
generalized pain 2
pedal edema 2
localized erythema 2
peau d'orange 2
heartburn 2
Delayed dermographism 2
Cholinergic pruritus 2
Respiratory symptoms 2
regurgitation 2
hemoptysis 2
neck stiffness 2
abdominal discomfort 2
acute abdominal pain 2
acute stress 2
leg edema 2
Ear swelling 2
acute pain 2
generalized abdominal pain 2
masculinization 1
Cardiovascular symptoms 1
Infantile colic 1
leg cramps 1
syncopal episodes 1
leg pain 1
hypocapnia 1
Bitot's spots 1
otalgia 1
polydipsia 1
hot flushes 1
localized edema 1
skin damage 1
urinary frequency 1
prickling sensation 1
Nasal symptoms 1
physical symptom 1
lassitude 1
spasticity 1
koilonychia 1
Overlying 1
more...
Drug
Dermatol 1020
Asthma 261
Omalizumab 96
Histamine 87
Honey 67
Loratadine 29
ampicillin 29
Allergen 24
Ketotifen 13
lysine 12
CSF 10
IFN-gamma 9
IL-2 9
Mizolastine 8
Ebastine 8
Diphenhydramine 7
ENT 7
caffeine 7
Rituximab 6
Dial 6
lactose 6
Bifidobacterium 5
Cardiovasc 5
Monit 5
Indomethacin 5
Azithromycin 4
Infliximab 4
Amoxicillin 4
Methylprednisolone 4
Captopril 4
Estrogens 4
nitroglycerin 4
Acacia 4
Atarax 4
Infliximab 4
MAP 4
p75 3
Gastro 3
Cimetidine 3
Zyrtec 3
Ecallantide 3
Xanthium 3
citric acid 3
Leaf 3
EE2 3
Iohexol 3
CTM 3
Omeprazole 3
Cimetidine 3
Zyrtec 3
Prednisone 3
Norplant 3
niacin 3
Taxol 3
Ranitidine 3
IL-1ra 3
Cremophor EL 3
Gel 2
Cetuximab 2
Asparaginase 2
Aloe 2
Biltricide 2
Zyban 2
Gleevec 2
Acyclovir 2
EPI 2
Acrivastine 2
Anakinra 2
Alesion 2
TES 2
Olopatadine hydrochloride 2
Kenyan 2
Mesalazine 2
MDM 2
vitamin E 2
Cinnarizine 2
Xylocaine 2
Phenytoin 2
ROS 2
Eusolex 2
Natalizumab 2
Eusolex 2
Papain 2
mepivacaine hydrochloride 2
Allegra 2
Clofibrate 2
Tranilast 2
Idursulfase 2
Allegra 2
Adalimumab 2
Imatinib 2
Alarin 2
Bactrim 2
Japanese encephalitis vaccine 2
Levonorgestrel 2
CAM 2
Iopamidol 2
Syrup 2
Antivenin 2
Cyanoacrylate 2
Lenalidomide 2
Nephron 2
Ethanol 2
IPD 1
Ketorolac 1
Iopromide 1
MDS 1
Portal 1
Thyroglobulin 1
Rokitamycin 1
EPA 1
TAC 1
DEL 1
ABC 1
Fluticasone propionate 1
Mononine 1
Aredia 1
Marcaine 1
Emedastine difumarate 1
Prozac 1
Norplant 1
Tinidazole 1
Plavix 1
Levocabastine 1
Synthroid 1
Gelfoam 1
VCR 1
Leucovorin 1
CTC 1
Iodixanol 1
Hexabrix 320 1
Vardenafil 1
Parsol 1
Plaquenil 1
Emla 1
Epinastine 1
Kelp 1
CCL 1
Gestodene 1
Trib 1
Copaxone 1
Dimethindene maleate 1
Primperan 1
CTM 1
Dipentum 1
HCH 1
FMOX 1
Zovirax 1
Bufexamac 1
NAG 1
Glafenine 1
Paxil 1
MgSO4 1
TAK 1
Pantopaque 1
Benzoic Acid 1
Quinine sulfate 1
Aldurazyme 1
Humulin 1
Fructose 1
more...
Enzyme
tryptase 51
trypsin 50
kallikrein 30
peroxidase 27
plasmin 23
thyroid peroxidase 20
ACE 20
alanine aminotransferase 18
ERK 16
superoxide dismutase 13
catalase 11
thrombin 10
diamine oxidase 9
SPT 8
focal adhesion kinase 8
SPT 8
mitogen-activated protein kinase 7
caspase-1 7
alkaline phosphatase 7
aspartate aminotransferase 7
P-glycoprotein 7
calcineurin 6
mevalonate kinase 5
lysozyme 5
AAE 5
CYP3A4 4
xanthine oxidase 4
phospholipase C 4
C1 esterase 4
urease 4
arylsulfate sulfotransferase 4
tissue plasminogen activator 4
prostate-specific antigen 4
chymase 4
lipoxygenase 3
lipase 3
NO synthase 3
chymotrypsin 3
asparaginase 3
monoamine oxidase 3
BAT 3
chymopapain 3
thromboplastin 3
lactate dehydrogenase 3
chymopapain 3
GSK 3
reverse transcriptase 3
neutrophil elastase 3
tyrosinase 3
pepsin 3
prostaglandin synthetase 3
acetylcholinesterase 3
lactase 3
glutathione peroxidase 3
hexosaminidase 3
FAST 3
cholinesterase 2
UDP-glucuronosyltransferase 2
glutathione S-transferase 2
papain 2
luciferase 2
chloramphenicol acetyltransferase 2
creatine kinase 2
CPN 2
transglutaminase 2
protein kinase C 2
urease 2
granzyme B 2
indoleamine 2,3-dioxygenase 2
phospholipase A2 2
elastase 2
gamma-glutamyl transpeptidase 2
ornithine decarboxylase 2
cathepsin G 2
Hageman factor 2
histidine decarboxylase 2
histamine N-methyltransferase 2
sulfite oxidase 2
lysin 2
renin 2
sulfite oxidase 2
DNA polymerase 2
caspase-3 2
CD13 1
complex I 1
hyaluronate lyase 1
cathepsin B 1
aminopeptidase P 1
transcriptase 1
MAT 1
SOR 1
CEP 1
aldehyde dehydrogenase 1
succinate dehydrogenase 1
RNA polymerase 1
MAT 1
EC 2.3.1.27 1
aldehyde dehydrogenase 1
pyruvate kinase 1
isocitrate dehydrogenase 1
SOR 1
C3 convertase 1
C3b inactivator 1
ferrochelatase 1
deaminase 1
C3 convertase 1
isocitrate dehydrogenase 1
carboxylesterase 1
glucose oxidase 1
beta-glucuronidase 1
AST 1
protein kinase 1
beta-secretase 1
thrombin-activatable fibrinolysis inhibitor 1
IKK 1
aldehyde dehydrogenase 1
arginine kinase 1
BMA 1
dipeptidyl peptidase IV 1
carboxypeptidase A 1
hyaluronidase 1
aldehyde dehydrogenase 1
hyaluronidase 1
urokinase-type plasminogen activator 1
Der p 1 1
proteinase-3 1
lipoprotein lipase 1
BMT 1
phosphorylase kinase 1
aldehyde dehydrogenase 1
cGMP phosphodiesterase 1
uricase 1
glucocerebrosidase 1
beta-lactamase 1
CEP 1
ricin 1
ALA synthase 1
NQO1 1
mannitol dehydrogenase 1
mannitol dehydrogenase 1
aspirin esterase 1
sulfatase 1
chondroitinase 1
MTD 1
Thy1 1
bromelain 1
acid phosphatase 1
legumain 1
phosphoinositide 3-kinase 1
NOS 1
murein hydrolase 1
transpeptidase 1
insulin-degrading enzyme 1
Compound
Clin 932
Dec 413
water 152
sodium 88
Histamine 87
ASA 72
DNA 69
sulfate 40
ethanol 40
oxygen 39
nickel 39
acetate 36
His 34
CAM 33
CAP 33
CAP 33
Pac 32
Cetirizine 31
potassium 31
calcium 30
benzoic acid 25
Caffeic acid phenethyl ester 24
iron 22
SDS 20
TNF 20
nitric oxide 20
creatinine 19
salicylic acid 18
vitamin D 17
iodine 17
salt 15
phosphate 14
LTC4 14
GPT 13
Fexofenadine 13
galactose 13
Terfenadine 13
formaldehyde 13
formaldehyde 13
nitrogen 12
Cardiol 12
methanol 12
lysine 12
Amantadine 12
zinc 12
hydroxide 11
leucine 11
Thyroid 11
vinyl 11
acetic acid 11
Cyclosporine 11
PGD2 11
Bradykinin 11
hydrogen 11
Adrenal 10
aldehyde 10
copper 10
glucose 10
barium 10
glutamate 10
urea 10
Doxepin 9
mercury 9
APAP 9
Chlorhexidine 9
LTE4 9
Imidacloprid 8
A 42 8
formic acid 8
formic acid 8
thymol 8
formic acid 8
Astemizole 8
Parenteral 8
formic acid 8
formic acid 8
DSS 8
formic acid 8
formic acid 8
formic acid 8
aldehyde 8
formic acid 8
formic acid 8
ammonium 7
PGE2 7
caffeine 7
ANA 7
acetonitrile 7
ethyl acetate 7
Diphenhydramine 7
Optimal 7
chromium 7
cadmium 7
Tartrazine 7
methyl nicotinate 7
ANA 7
ATP 6
PPD 6
GD3 6
6-12 6
cysteine 6
Dial 6
Penicillin 6
Penicillin 6
methionine 6
Estrogen 6
Phe 6
PPD 6
DMSO 6
hexane 6
noradrenaline 6
TSH 6
COX 6
Insulin 5
piperazine 5
A 3 5
DPPH 5
bromide 5
Montelukast 5
Chlorpheniramine 5
kaempferol 5
GSH 5
Hemoglobin 5
cobalt 5
BRL 5
propylene glycol 5
Chlorpheniramine 5
GSH 5
Isoproterenol 5
LIN 5
Vitamin D 5
Indomethacin 5
Off 5
phenol 5
propylene glycol 5
Minocycline 5
Argentine 4
Amoxicillin 4
tyrosine 4
alanine 4
PGE 4
quinoline 4
Coumaphos 4
Ethylene oxide 4
A 71 4
2-hydroxyethyl 4
Azithromycin 4
quinoline 4
glycerol 4
oxalic acid 4
PAP 4
methylhistamine 4
PAP 4
Paclitaxel 4
Salix 4
Yellow 4
Etanercept 4
AMP 4
Arachidonic acid 4
arginine 4
more...