Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Solar urticaria was treated by means of repeated exposures of the skin to fluorescent lamps or natural sunlight. Repeated exposures over a period of hours induce a state of tolerance in the skin so that urticaria fails to develop. The state of tolerance can be maintained with regular daily exposures, and treatment can lead to complete symptomatic relief. Determination of the action spectrum for urticaria is advisable in order to choose the correct fluorescent lamp for treatment.
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PMID:Solar urticaria treatment by inducing tolerance to artificial radiation and natural light. 90 Sep 66

It is possible in the majority of patients with polymorphic light eruption to produce lesions experimentally. Only the reproduction of the clinical reaction is significant for the diagnosis. Irradiation is carried out in the same test area two or three times with a dose of up to eight times the minimal erythema dose. Sunlight is the best agent for the evaluation of this protocutaneous disorder. A localised area of the skin can be exposed to midday sunshine about half an hour on three consecutive days. But sunlight has the disadvantage of having a variable ultraviolet emission at different times. It is necessary to differentiate lupus erythematosus and photocontact dermatitis, which may produce identical reactions. Other light sources are the hot quartz lamp, fluorescent tube "sun lamp", solar simulator and the monochromater. Patients with polymorphic light eruption are sensitive to light in the range 300 to 320 nm. but some of them are sensitive to savelengths shorter or longer than this range. The methods of protection against solar radiation which have been tried include: 1) Avoidance of sunlight; 2) Promotion of melanin hyperpgimentation and thickening of the stratum corneum-by controlled exposure to sunlight; 3) Application of a film of a chemical compound that will act as a physical screen and absorb, scatter or reflect damaging radiation; 4) Chemical modification of the stratum corneum by topically applied substances which can conjugate chemically or be absorbed onto the stratum corneum and filter the damaging rays. Many authors at present consider the use of alcoholic solutions of para-aminobenzoic acid (PABA) to be the most effective method of preventing reactions from exposure to sunlight. Pathak and Fitzpatrick showed that 5 % PABA in 70 % ethanol and 2,5 % Escalol 506 in 65 % ethanol is the most effective sunscreen against radiation of the sunburn spectrum. A dihydroxyacetone (DHA) and naphthaquinone (lawsone) sunscreen provides photoprotection for all types of photosensitivity throughout the whole UV spectrum even into the visible region. Systemic photoprotection: The administration of beta-carotene to patients with erythropoietic protoporphyria has resulted in amelioriation of their photosensitivity. Antimalarials are valuable therapeutic agents and are highly effective in controlling cutaneous lupus erythematosus, polymorphic light eruption and occasionally solar urticaria.
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PMID:[Polymorphic light dermatitis. Photobiology and photoprotection]. 98 44

2380 sessions of ultraviolet blood irradiation have been analysed. A DRB-8 lamp was used as a source of irradiation. The complications observed were divided into 2 groups. Group 1 comprised complications associated with the technical performance of the manipulation, their rate being 1.3%. Group II comprised complications developed in ultraviolet blood irradiation. The complications observed in group II were as follows: rigor in 4 cases, hypotension in 2 cases, nasal bleeding in 3 cases, hypoglycemia in 1 patient, bronchospasm in 1 patient and urticaria in 1 patient. To prevent the onset of complications medical care and the oral intake of carbohydrates are recommended for 1.5-2 h after the session. Intramuscular injections are to be avoided for 1.5 h for fear of the appearance of hematomas.
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PMID:[Complications in ultraviolet irradiation of the blood]. 207 72

Purpura is provoked when the affected area is warmed up to 40 degrees C by means of an infrared lamp in cryoglobulinemia after exposition to cold with consecutive urticaria. For this way of causing purpura in two steps, we suggest the designation "bithermo-test".
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PMID:[Purpura following bithermotest in cryoglobulinemia]. 359 Sep 15

Solar urticaria, an uncommon photosensitivity disorder, may be disabling for affected patients, especially those who react after short exposures to artificial or natural light. The spectrodermograph, a newly developed instrument, permits rapid, accurate determination of the action spectrum of solar urticaria. It consists of a xenon arc lamp with an emission dispersed into used to establish the wavelengths responsible for solar urticaria in 12 patients during the past four years. Knowledge of the wavelengths responsible for producing the urticarial reaction has implications for selecting appropriate therapy. The clinical course of these patients is also reviewed.
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PMID:Solar urticaria. Clinical features and wavelength dependence. 706 79

A 42-year-old woman acquired solar urticaria approximately ten minutes after exposure to sunlight. Urticaria developed from visible light emitted from a projector lamp after a similar time lag. Monochromatic rays between 400 and 500 nm induced immediate urticaria by irradiation, with four times the minimal urticarial dose. Urticaria that was induced by monochromatic rays of the projector lamp was completely inhibited by immediate reirradiation of test sites with light waves longer that 530 nm. Radiant heat exposure from an electric hair dryer at 50 degrees C had no suppressive effects on the development of urticarial lesions.
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PMID:Solar urticaria. Determinations of action and inhibition spectra. 708 28

Physicians may administer intravenous dyes to patients, most commonly to delineate vascular or urinary anatomy, without an appreciation of the potential hazards associated with these compounds. We report two cases in which skin eruptions followed the intravenous administration of the dyes fluorescein and methylene blue; these eruptions were the same colors as the dyes. In our first patient, urticaria, which was yellowish in color and fluorescent under a Wood's lamp, occurred after the administration of fluorescein. In the second patient, painful blue macules appeared randomly on the forearm within 15 seconds after methylene blue was injected into a free-flowing intravenous cannula on the dorsal aspect of the hand.
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PMID:Dye rashes. 1007 43

THE CHIEF POINTS PRESENTED IN THIS PAPER ARE: 1. Following the ingestion of buckwheat (plant or seed) varicolored guinea pigs, white swine and goats exhibited symptoms of photosensitization, the degree of sensitization being in the order given. 2. Rabbits, dogs, white mice and rats did not manifest symptoms of photosensitization. 3. The symptoms and reactions were: agitation, itching, scratching of the ears, weakness, urticaria with sloughing and symptoms similar to those in anaphylaxis. 4. Microscopic examinations showed the lack of marked pathologic change. The lesions, such as petechial hemorrhage of the lungs, brain, liver, stomach and kidneys, suggest that profound toxemia has been present. 5. Lesions were not found which appeared to be suggestive of malignant neoplasms. 6. Irradiation by a quartz mercury vapor lamp apparently develops a resistance to photosensitization, probably because of increased pigmentation induced by ultra-violet light. 7. From the nature of the physiologic and pathologic reactions produced under various filters and from a consideration of the percentages of transmission of solar energy in the visible spectrum, it would seem that the region of photosensitization lies between 580 millimicrons (yellow) and the red end of the spectrum. This conclusion, moreover, is substantiated by the fact that irradiation by a quartz mercury vapor lamp (which radiates no energy in the visible spectrum at a wave-length greater than 579 millimicrons) produces no symptoms or reactions. 8. Spectrophotometric determinations of alcoholic extracts of grass (non-toxic) and of buckwheat (toxic) show the presence of two additional bands in the absorption spectrum of buckwheat with maxima at about 540 and 600 millimicrons, respectively, together with the common absorption zones at 430 to 490 millimicrons and 630 to 690 millimicrons. 9. Spectrophotometric determinations of blood serums of sensitized animals show, besides the usual absorption bands peculiar to oxyhemoglobin (with maxima at 540 and 580 millimicrons respectively), two zones with maxima at 600 and 660 millimicrons respectively. 10. The fluorescence of chlorophyll per se, as suggested by previous investigators, is not, in all probability, the cause of the sensitization induced by buckwheat. 11. Hematoporphyrine is not the photodynamic substance in all probability. 12. Phylloporphyrine may be the photodynamic substance. In this regard, also, the possibility of cholehematin is not to be ruled out.
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PMID:PHOTOSENSITIZATION OF ANIMALS AFTER THE INGESTION OF BUCKWHEAT. 1986 46

A 21-year-old male patient with no history of systemic disease or drug use presented to our clinic with redness and pain in the right eye. Best corrected visual acuity was 20/20 in both eyes. Inflamed pinguecula was observed on slit-lamp examination and the patient was prescribed ophthalmic nepafenac eye drops. After instilling the drops that day and the next day, the patient presented again due to pruritus and rash. Upon consultation with the dermatology department, the patient was diagnosed with drug-induced allergic urticaria and the nepafenac drops were discontinued. Although urticaria has been reported as a side effect after systemic non-steroidal anti-inflammatory drug (NSAID) use, such a reaction has not been reported with an ophthalmic NSAID and ours is the first reported case of urticaria following ophthalmic nepafenac use. This unique case highlights the fact that ophthalmologists must also keep urticaria in mind as a potential side effect when prescribing this drug.
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PMID:A Case of Allergic Urticaria After Ophthalmic Nepafenac Use. 2998 79