Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A report is given on a travel to Elba, the largest island of the Tuscany archepelago (Italy) and a holiday place preferred by German speaking tourists. In the last years some cases of visceral leishmaniasis and oriental sores, respectively, were introduced to Germany from this island. The geoecological background of this development was investigated. Reproduction and spread of the most abundant sandfly species Phlebotomus (Laroussius) perniciosus favour ruinous buildings, actually used as animal shelters sometimes in the immediate vicinity of new tourist bungalows. A typical allergic response upon sandfly bites occurs in almost all of the newcomers. This skin irritation is wellknown as urticaria multiformis endemica of Harara. Local people and tourists connect this itching disorder with certain types of sun trauma and do not take notice of their real etiology. Cortisone treatment in severe cases may facilitate the start of simultaneously transmitted leishmaniasis. The possible epidemiological role, which the dog travelling to southern countries in connection with leishmaniasis plays, is considered.
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PMID:[The Elba triad: harara, light dermatoses, leishmaniasis. The ecological background]. 701 13

Cortisone and corticotropin (ACTH) in adequate doses usually promptly relieve allergic rhinitis, bronchial asthma, atopic eczema, urticaria, drug reactions and poison oak and ivy dermatitis. However, as the symptoms recur upon discontinuance of the hormones, and longcontinued use entails certain hazards, it is necessary to determine the underlying allergic cause of the symptoms and to institute measures to overcome it. However, when adequate antiallergic treatment does not control symptoms, the continued use of small doses of these steroids or of larger doses for weeks or months in severe or intractable cases is justified. In the few cases in which prolonged use of these hormones is necessary, the patient ought to be told of the possible complications, of the expense of laboratory studies that must be carried out, and of the cost of the hormones.
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PMID:Cortisone and corticotropin in allergic disease. 1300 99