Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Tranilast is an anti-allergic drug clinically used for the treatment of atopy or urticaria. The drug has been shown to have an anti-fibrotic effect as well. We treated two cutaneous sarcoidosis patients with tranilast, resulting in remission within three months of administration. This drug should be an excellent tool for the treatment of other granulomatous diseases.
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PMID:Treatment of cutaneous sarcoidosis with tranilast. 753 63

Tranilast (Rizaben) is an antioxidant and an antiallergic antiangiogenesis, and anti-inflammatory agent that has been used to treat disorders ranging from bronchial asthma to keloids to oligozoospermia. In addition to its application in such therapeutically challenging conditions, tranilast in topical form provides relief from many relatively minor but compromising discomforts, such as hives or seasonal nasal congestion, that affect the quality of everyday life. Easily compounded and easy to apply, topical tranilast is a popular preparation sought in many compounding pharmacies. Larry J. Frieders, RPh, owner of The Compounder in Aurora, Illinois, describes his innovative use of tranilast and explains the value of that drug in the compounding armamentarium. The brief case reports of two staff members of The Compounder attest to the success of treatment with tranilast.
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PMID:Innovative Uses of Compounded Tranilast: An Interview with Compounding Pharmacist Larry J. Frieders, RPh. 2397 19