Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ammonium persulfate is widely used to "boost" peroxide hair bleaches. These persulfates can produce a variety of cutaneous and respiratory responses, including allergic eczematous contact dermatitis, irritant dermatitis, localized edema, generalized urticaria, rhinitis, asthma, and syncope. Some of these reactions appear to be truly allergic while others appear to be due to the release of histamine on a nonallergic basis. Patch tests may be performed with 2% to 5% aqueous solution of ammonium persulfate. Scratch tests may result in asthma and syncope. In some patients, merely rubbing a saturated solution of ammonium persulfate into the skin will evoke a large urticarial wheal. Hairdressers should be made aware that these ammonium persulfate hair bleach preparations may provoke severe reactions and should seek medical attention if the client complains of severe itching, tingling, a burning sensation, hives, dizziness, or weakness.
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PMID:Persulfate hair bleach reactions. Cutaneous and respiratory manifestations. 96 35

There is an increasing incidence of contact urticaria (CU) and systemic reactions to rubber products. 34 patients are presented: Most were atopic (22/34) and women (29/34). 24 worked in the medical field. 13 patients showed signs of hand dermatitis. In 31 patients, rub and/or pricktests with liquid latex in different dilutions and with latex gloves led to positive reactions. The allergen(s) appear in part to be watersoluble: 23 of 31 patients revealed positive test reactions to an aqueous glove extract. In two patients, urticarial test reactions to TMTD, Mercapto-Mix, and PPD-mix were considered as possible contributing factor of CU. Scratch tests with corn-starch were negative in all patients. 17 of 29 sera showed RAST (radioallergosorbent test) class 0 using latex allergen disks. SDS-PAGE (sodiumdodecylsulfate-polyacrylamide-electrophoresis) determined protein bands of less than or equal to 14 kD (not allergen specific) and approximately 28 kD. The Western Blot detected the 28 kD protein as allergen in the sera of three patients. Isoelectric focusing (IEF) proved no protein bands. Immunoprinting performed with sera of five patients presented allergen bands in an pH range between 3.8 and 4.55. This shows that radiostaining (immunoprint) is more sensitive than the Coomassie Blue staining. Although three sera showed RAST class 0, immunoblotting detected allergen bands. In these cases the immunoblot appears to be more sensitive than the RAST. A cross reactivity between latex and banana could not be established. Alternative gloves are Neolon (neoprene) or Elastyren (styrene-butadiene polymer).
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PMID:[Immediate allergic reaction to natural latex with special reference to surgical gloves]. 138 94

We report on veterinarians showing itching, swelling, and urticaria on hands and arms after contact with amniotic fluid of cows and/or pigs. Scratch tests with the corresponding fluid gave positive results. RAST investigations were done with self-prepared allergen discs. In all 6 cases, the RAST on amniotic fluid was positive, correlating well with the results of the skin tests. RAST tests on sera from the cattle were positive, too, whereas tests on the epithelia remained negative. Our findings show that the allergen causing contact urticaria is a compound of amniotic fluid and serum but not of the epithelia of these animals. Thus we can conclude that sensitized veterinarians do not have to avoid all contact with these species, but we recommend special protection.
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PMID:[Detection of specific IgE antibodies in veterinarians with contact urticaria]. 293 18

In 164 patients with chronic recurrent urticaria, the value of skin tests was investigated, Patch tests carried out with the standard series of the International Contact Dermatitis Research Group and with a series of penicillins revealed positive reactions in 22 (35/162) and 6.9% (11/158), respectively. IN 21.5% (33/152) positive intracutaneous tests to cilligen and/or penicillin G were observed. 35% (51!147) of the patients had one or more positive intracutaneous tests with inhalants. Scratch tests with food allergens showed positive reactions in 12.5% (12/95). There was no difference in results between patients with idiopathic urticaria or angio-oedema and those with physical urticaria. The value of these findings is discussed. Most of the patients with penicillin allergy, were recommended to be on a diet free from milk and milk products. In 50% this was successful.
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PMID:Skin testing in chronic urticaria. 645 49

Comparative study of 13 patients (group A) with severe attacks of angio-oedema and urticaria after eating celery and 143 atopics with hypersensitivity to mugwort-pollen (group B). Due to the severity of the reactions (group A) no oral provocation tests were performed. Scratch chamber tests with raw and cooked celery (and related plants) confirmed the case histories. RAST answers to celery were compared for both groups. RAST inhibition indicated that celery and mugwort-pollen and also celery and birch-pollen allergens cross-react. Whether or not the reactions (in group A) are type I allergic or non-specific reactions is discussed. The term celery-"contact urticaria syndrome" should be used (Maibach and Johnson, 1975).
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PMID:[Celery allergy (celery contact urticaria syndrome) and relation to allergies to other plant antigens]. 667 Feb 80

A 27-year-old woman had for 2 years performed manual grinding of metal castings that contained nickel. She had previously had allergic contact dermatitis from nickel but started to get contact urticaria, rhinitis and asthmatic attacks at work. The symptoms disappeared at weekends and on holiday. Scratch chamber tests, open tests, specific IgE determinations (RAST), and RAST-inhibition test indicated that she had developed an IgE-mediated allergy to nickel; the bronchial provocation reaction with NiSO4 was, however, a late one. Patch tests confirmed her allergic contact dermatitis to be caused by nickel. This is the first patient, to the best of our knowledge, reported to have developed allergic contact dermatitis, allergic contact urticaria, rhinitis and asthma from nickel.
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PMID:Immediate and delayed allergy to nickel with contact urticaria, rhinitis, asthma and contact dermatitis. 831 28

A 37-year-old meat inspector presented with a 5-month history of forearm eczema. His symptoms improved at weekends and over holidays but flared within a day of work. Scratch patch tests were strongly positive to fresh venison diaphragm and venison liver and weakly positive to venison hide and blood, and lamb blood. They were negative to other venison and lamb components. Type IV allergy tests with Standard European and fragrance batteries were negative. The eczema cleared with a change in work role, clobetasol-17-propionate cream, flucloxacillin and aqueous cream. He was then able to return to meat inspecting. Provided he was diligent about applying 'Dermashield' barrier foam and minimizing contact with irritants, his eczema has remained well controlled over the last 4 years. Attention to irritant contact dermatitis is important in the management of protein contact urticaria.
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PMID:Venison contact dermatitis. 1186 15