Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042109 (
urticaria
)
6,569
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Contact urticaria may occur following contact of the skin or mucous membranes with a large number of diverse substances. When localized angioedematous reactions of the eyes or oropharynx are caused by proteinaceous substances, the distinction between contact
urticaria
and common inhalant or food allergies is subtle. The time course of the reaction, negative controls, or occurrence of generalized symptoms do not constitute unequivocal evidence of immunologic contact
urticaria
, and confirmation by RAST or passive transfer testing is required. Clinical symptoms range from mild,
localized erythema
to generalized anaphylaxis. When contact
urticaria
becomes superimposed on eczematous skin, immediate reactions that resemble eczema more than
urticaria
may occur. Dermatologists must increase their awareness of these clinical reactions and evaluate the external environment when searching for causes of localized urticarial reactions.
...
PMID:The contact urticaria syndrome. 391 89
A case of contact
urticaria
to the silicone rubber in the MCU-2A/P gas mask is presented. Contact urticaria is a type I hypersensitivity reaction mediated by immunoglobulin E that usually manifests as
localized erythema
, edema, pruritus, and urticarial plaques. It can also cause systemic reactions, including anaphylaxis. Allergic reactions to silicone rubber have been increasingly reported and are of importance in medical and military personnel. The implication of such a diagnosis in an active duty military member is significant because the individual cannot be worldwide-qualified. The correct diagnosis of allergic skin reactions to personal protective gear is critical to maintaining a strong fighting force and protecting military personnel from potentially life-threatening allergic reactions.
...
PMID:Contact urticaria to the MCU-2A/P gas mask. 1033 82