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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A few minutes after sucking a lozenge for a sore throat a 68-year-old man developed an anaphylactic shock. At a heart rate of 110/min there was no palpable blood pressure. A red confluent exanthem, predominantly of the trunk, was noted. After brief intensive-care treatment the patient was completely well again and diagnostic tests for allergy were performed. The prick test for the 14 individual ingredients of the throat lozenge produced massive reddening and urticaria on the test arm with carbowax, a polyethylene glycol which serves as a vehicle in the remedy and does not have to be listed. Later there were an urge to cough and urticaria all over the trunk. There was no systemic reaction. Neither specific IgE antibodies nor any complement-consuming reaction could be demonstrated. Thus the precipitating mechanism remains unexplained.
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PMID:[Anaphylactic shock after sucking on a throat lozenge]. 169 39

Exercise-induced asthma is a common but frequently undiagnosed problem. The patient may not wheeze, but rather have shortness of breath, chest tightening, and coughing. The coach and the physician must be particularly alert to the signs and symptoms of exercise-induced asthma to recognize this syndrome. Proper conditioning, warming up, inducing refractoriness, participating in sports less likely to provoke exercise-induced asthma, and the aggressive use of appropriate medications allow patients to enjoy sports and compete effectively. A rare but potentially fatal syndrome is exercise-induced anaphylaxis. Accurate diagnosis and differentiation from other exertion-related syndromes are critical, and appropriate precautions are necessary. A third clinical entity, exercise-induced cholinergic urticaria, although not life-threatening, can be quite annoying. Aggravating factors, such as increased heat, compound the problems. In summary, exercise-induced allergic phenomena are common and should be recognized by the practicing physician.
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PMID:Exercise-induced asthma, anaphylaxis, and urticaria. 178 58

In a national study of almost 7000 primary school children, parents' perceptions were used to test the hypothesis that the child's irritability was associated with food intolerance independently of other symptoms. After adjustment in a multiple regression analysis for asthma or wheeze, cough, eczema, hives, diarrhoea and vomiting, rhinitis, hay fever and headache, and the social factors of father's social class, maternal education and maternal age, a highly significant association between perception of food intolerance and irritability (P less than 0.001) remained. Though we cannot rule out that irritable children's parents could be biased towards diagnosing food intolerance the possibility that some children do have behavioural disturbance associated with reactions to food needs to be explored further, preferably with a double blind challenge assessment.
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PMID:Associations of excessive irritability with common illnesses and food intolerance. 236 72

Oral and/or parenteral amoxycillin was used to treat 52 young and adult patients suffering from moderately severe to severe bronchitis, bronchopneumonia or acute lobar pneumonia. The mean time between onset of disease and start of treatment was 3.8 days. Patients received doses of amoxycillin ranging from 375 mg to 1 g 2 to 3-times daily depending on the severity of the condition for a mean of 6.4 days. There was complete resolution of clinical symptoms such as fever, cough and pleural pain after 3 days in all but 3 of the patients. Response was considered excellent or good in 77% of patients and satisfactory in 14%. Mild to moderate side-effects such as urticaria and nausea were reported in 8 patients but were not severe enough to interrupt treatment. Overall, amoxycillin was considered to be effective in 82% and partially so in 11% of the patients treated.
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PMID:[Oral and parenteral amoxicillin in the treatment of pneumonia and acute bronchitis]. 259 21

Exercise and physical fitness are becoming increasingly popular in our society. As a result there are more individuals who are at risk for the development of acute respiratory emergencies associated with sports and athletics. EIB is a common feature of asthma and is characterized by a postexercise fall in FEV1 of more than 10 per cent. Although a variety of medications have been used for the prevention of EIB, cromolyn sodium and inhaled adrenergic agonists have been shown to be the most effective. EIA and cholinergic urticaria are two physical allergies in which hypotension can be brought on by exercise. In some individuals, EIA develops only in association with the ingestion of a particular food. Associated with sports and recreational activities in alpine areas is the risk of developing acute high-altitude medical problems. One of the most dramatic and potentially life threatening is high-altitude pulmonary edema. The management of this condition can be problematic, particularly if rapid descent to lower elevations is not possible. Although rare, spontaneous pneumothorax and pulmonary emboli do develop in the otherwise well-conditioned athlete. These entities must be considered when the physician evaluates any athlete in whom acute cough and dyspnea develop.
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PMID:Acute respiratory emergencies in emergency treatment of the injured athlete. 266 79

We assessed the relationships of clinical symptoms and serum antibody levels during follow-up of 47 patients, aged 3 to 66 months, who were shown by formal milk challenge to have cow milk allergy. Three groups of patients were identified. Group 1 patients (n = 15) were sensitized to IgE and responded rapidly to small volumes of milk with urticaria, an exacerbation of eczema, wheeze, or vomiting. In the second group (n = 24), symptoms of milk enteropathy (vomiting and diarrhea) developed between 1 and 20 hours after milk ingestion. In the group 3 patients (n = 8), coughing, diarrhea, eczematoid rashes, or a combination of these developed more than 20 hours after normal volumes of milk were given. Serum levels of IgG, IgA, IgM, and IgE and of milk-specific anti-cow milk antibodies of these isotypes were measured initially and then at a median follow-up time of 16 months (range 6 to 39 months). In this investigation, changes in these immunologic measures during the study period were related to whether or not clinical tolerance to cow milk was achieved. At follow-up, six patients from group 1, ten from group 2, and two from group 3 were milk tolerant. No consistent change in any of the immunologic measurements was associated with remission of the disease. These findings raise the question of whether acquisition of clinical tolerance to cow milk in cow milk allergy can be attributed solely to immunologic events.
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PMID:Recovery from milk allergy in early childhood: antibody studies. 271 89

To identify and measure the incidence of adverse effects of the angiotensin converting enzyme inhibitor enalapril 13,713 patients were studied for one year by prescription-event monitoring. Precise information about the duration of treatment was available for 12,543 patients. The frequency of many events was calculated, including dizziness (483 patients; 3.9%), persistent dry cough (360; 2.9%), headache (310; 2.5%) hypotension (218; 1.7%), and syncope (155; 1.2%). Less common reactions included angioedema, urticaria, and muscle cramps. Altogether 1098 (8%) patients died and the notes of 913 of them (83%) were obtained for detailed scrutiny. With the exception of a few patients with renal failure who deteriorated during treatment (reported on separately), no death was attributed to enalapril. Enalapril was considered to be effective, even in patients with advanced cardiac failure. These results for enalapril are reassuring and provide further evidence of the value of prescription-event monitoring.
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PMID:Postmarketing surveillance of enalapril. I: Results of prescription-event monitoring. 284 1

Bronchial hyperreactivity was studied in 79 patients who gave a history of allergic symptoms. Twenty-nine of them suffered from rhinitis, 28 from eczema, 21 from urticaria and one from gastrointestinal allergy. Forced expiration in the first second (FEV1) was measured in each. If FEV1 was greater than 1 l a histamine challenge was done. Histamine (0.6 mg/ml) was inhaled by tidal breathing for one minute. FEV1 was measured before the inhalation and two min after cessation of the inhalation. If FEV1 dropped greater than 20% the inhalation was assessed as positive and the provocation was stopped. If the challenge was not positive another inhalation with histamine (2.4 mg/ml, l min) was done. If FEV1 dropped greater than 20% when measured two min after the inhalation the provocation was called positive. Twenty-two patients with rhinitis had a negative bronchial challenge, six had a positive. One of them had asthma, three suffered also from cough and/or serous sputum production, and two had hay fever. Out of 28 with eczema, 20 had negative histamine challenge and five a positive. Four of these suffered from daily cough and/or serous sputum production, one had no airway symptoms. Fifteen out of 21 suffering from urticaria had a negative histamine challenge, three had a positive. Two of them suffered from asthma and one complained of daily cough and/or serous sputum production. It is concluded that allergic subjects without symptoms from the airways, have a bronchial reactivity to inhaled histamine similar to the general population.
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PMID:Bronchial hyperreactivity in allergic subjects. 346 10

Out of 2.513 clinical files of allergic children, we have found 200 pollen-allergic patients, which represent 7.9% of the total allergic pathology in children, in our environment. We have studied in these 200, the most important epidemiological parameters and the influence that this can cause upon the characteristics of this disease. A male predominance has been found (70%) and it has been discovered that 52% of the total were born in spring (p less than 0.0005). An hundred per cent have shown grass-pollen sensitiveness and 52% have also shown other kinds of pollen hypersensitivity. It has been found familiar allergic background in 76.5% of the cases and in 32.5% familiar allergic history of pollinosis. Unexpectedly, those who were in lack of familiar allergic history began their clinical symptoms earlier; 51.06% before 6 years of age (p less than 0.05). Other kinds of allergic manifestations were found in 51%, being respiratory symptoms the most important (35.5%), followed by the cutaneous (23.5%) and digestive ones (10.5%). Allergy to drugs was found in 10.5%. The more frequent symptoms of pollinosis were in order of importance: rhinitis (86.5%), conjunctivitis (77%), asthma (48%), spasmodic cough (27.5%) and urticaria (4%). Asthma induced by grass-pollen hypersensitivity was equally suffered by the males as by the females, and this was more frequent among the patients who had previously suffered from non-pollinic respiratory allergies.
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PMID:[Natural history of pollinosis in childhood]. 370 20

A nasal provocation test was performed by consecutively placing allergen discs on the nasal mucosa of patients with pollinosis. This brought easily the systemic symptoms such as cough, periorbital oedema, and urticaria. Similarly, the nasal administration of large doses of the allergen induced a change in the respiratory response in sensitized guinea pigs. These results indicate that nasal mucosa absorbs a high molecular substance such as allergens.
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PMID:The mechanisms of systemic symptoms following nasal administration of allergens. 403 44


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