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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The author observed that in the throat and/or nasal culture of approximately 80% of little children admitted to hospital with urticaria-like toxic-allergic exanthem, exotoxin-producing strains of Staphylococcus aureus could be isolated. In 15 of the 19 cases presented. Toxic Shock Syndrome Toxin (TSST-1) and in 4 cases various enterotoxins were identified. With aimed antibiotic treatment the skin symptoms of the children healed up in 3-4 days. Thus, the following question is raised: when facing the Toxic Shock Syndrome Toxin for the first time, why do children develop only skin symptoms, without severe complications of the Toxic Shock Syndrome observed in adult patients. It is assumed that similarly to classic infectious diseases, the course of the illness is milder in little childhood and the frequency of complications are lower than in adulthood. This phenomenon may be attributed to the immature immune reactivity of little children.
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PMID:[Relationship between urticaria-like toxic allergic exanthema and infection by toxin-producing Staphylococcus strains in infants]. 799 Dec 43

Early recognition and treatment of life-threatening dermatoses can reduce morbidity and mortality. Pemphigus vulgaris can usually be brought under control with high doses of corticosteroids. In cases of necrotizing fasciitis, early, extensive debridement of involved tissue is essential, since antibiotic therapy alone has little effect. Patients with toxic epidermal necrolysis and occasionally those with Stevens-Johnson syndrome may need care similar to that required for a major burn. Therapy for toxic shock syndrome includes aggressive fluid replacement and beta lactamase-resistant antistaphylococcal antibiotics. Treatment of urticaria and acquired angioedema includes histamine receptor blockers, prednisone (for intractable cases), and epinephrine (for respiratory compromise); danazol (Danocrine) or stanozolol (Winstrol) may be useful for prophylaxis of hereditary angioedema.
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PMID:Dermatologic emergencies. When early recognition can be lifesaving. 793 18

A series of 30 cases of Kawasaki disease has been studied retrospectively over a period of 11 years. The aim was to reassess the diagnostic value of the dermatological manifestations. A modification of the extremities was observed in 28 patients (23 had early inflammatory lesions, 25 had late desquamation). Exanthema was constant, polymorphous and most often urticaria-like. Vesicles, pustules or purpura were noted during the course of the eruption in 7 patients. A perineal eruption was observed in 17 cases and was found of good diagnostic value even though not pathognomonic. Cheilitis was the most frequent of buccopharyngeal modifications (93 p. 100). Conjunctival hyperemia was noted in 26 patients. Eight children had cardiovascular complications. Among these cases, the modification of the extremities seemed to be more pronounced and stomatitis and arthritis were apparently more frequent. Most of all, the inflammatory syndrome was significantly more severe as concerns CRP and polymorphonuclear leukocytes counts. Dermatological examination often rules out other diagnoses, such as measles, scarlet fever and staphylococcal toxic shock syndrome. However, a complete etiological workup remains mandatory.
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PMID:[Cutaneous manifestations of Kawasaki disease. Apropos of 30 cases]. 816 Nov 12

Preview Several dermatoses are potentially fatal, and the mortality rate for some is quite high; prompt recognition and treatment are essential. Dr Gannon's succinct discussions of pemphigus vulgaris, necrotizing fasciitis, toxic epidermal necrolysis, Stevens-Johnson syndrome, toxic shock syndrome, and urticaria and angioedema will leave physicians well prepared to quickly identify these diseases and provide appropriate treatment.
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PMID:Dermatologic emergencies. 2921 50