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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Ophthalmological lesions enter in the definition of Cogan's syndrome, associated with vestibulo-auditory symptoms. They are present in almost one half of patients with Wegener's granulomatosis and in 10 to 20 p. 100 of patients with periarteritis nodosa, where they may be the initial symptom. Yet they are seldom described in leucocytoclastic angiitis of small vessels, 3 cases of which are reported here. The first case concerns a 71-year old woman with cutaneous leucocytoclastic angiitis which regressed within a few days under dapsone. However, the drug had to be withdrawn on account of acute haemolysis. Thereafter, new skin lesions and severe pain in the left eye with fall in visual acuity developed simultaneously. Eye examination showed a large, marginal ulceration of the cornea extending to the adjacent sclera and reflecting deep involvement of the sclerocorneal limbus. Systemic corticosteroid therapy in doses of 1 mg/kg/day was instituted, resulting in gradual disappearance of the skin lesions and stabilization of the ophthalmic lesion. There remains, however, thinning of the cornea and sclera which entails a definite risk of perforation should the angiitis recur. The second patient was a 54-year old man seen for fever, polyarthralgia, purpura of the lower limbs and rapidly extending necrotic ulceration of the scrotum. A few days previously, inflammatory chemosis of the right eye had suddenly developed. Under systemic corticosteroids (1.5 mg/kg/day), the ophthalmic symptoms rapidly regressed, but the patient died of digestive tract haemorrhage. The third case was that of a 36-year old woman with urticaria associated with arthralgias and diffuse myalgia.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Ophthalmologic manifestations of leukocytoclastic vasculitis. Apropos of 3 case reports]. 357 12

Condom sales rose in the 1980s because condoms protect against the spread of sexually transmitted diseases and AIDS. In anticipation of corresponding increase in the incidence of condom dermatitis, a dermatologist prepared a brief overview of the condition and ways to treat it to prepare health professional for the anticipated increase. In men, allergic reactions may consist of edema of the penis, especially the prepuce; penile itching; and eczematous dermatitis which extends to the scrotum, inguinal areas, and the inner thighs. Symptoms in women vary and may include pubic and groin dermatitis, vulvitis, pruritus vulvae, a burning vaginal sensation, vulval redness and edema, and eczema on nearby skin. Antioxidants or accelerators in the rubber are generally responsible for condom dermatitis. When a health professional believes the dermatitis to be allergic rubber condom dermatitis, he/she should request patch tests for the same make of condom that came in contact with the patient and for rubber chemicals known to induce an allergic reaction, e.g., mercaptobenzothiazole (MBT). To assist, the dermatologist includes a patch test series for such allergens. Natural latex condoms and condoms made of processed sheep intestine cecum may prevent most allergic reactions. Sometimes patients are allergic to condom lubricants, and not the rubber itself. Health professionals must be sure to inform dermatitis patients allergic to the lubricant to not switch to oils or petroleum jelly because they destroy the rubber. Spermicidal contraceptive agents also can cause contact dermatitis, particularly nonoxynol 9. A condom with corn starch can produce urticaria. Further, paralyzed male patients are especially prone to allergic dermatitis from either the rubber in the condom urinals and/or the medical adhesive.
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PMID:Condom dermatitis in either partner. 358

Urticaria is a common complaint characterized by the eruption of cutaneous wheals, accompanied by redness and itching and in which mast cells are thought to play a central role. Wheals range from a few millimeters to several centimeters in diameter and are usually short lasting, except in case of urticarial vasculitis in which they last longer than 24 hours. Urticaria may occur alone or be associated with angioedema, that can be defined as a deep dermal and subcutaneous edema typically affecting the lips, face, hands, feet, penis or scrotum. Angioedema may also involve the submucosal tissue, and when the swellings occur in the oropharynx they can be alarming and occasionally life-threatening. In many cases the cause of acute urticaria or angioedema may be determined, whilst the pathogenetic and diagnostic aspects of the chronic forms are more complex and variable. The clinical features of, as well as the diagnostic and therapeutic approaches to the different forms of urticaria and angioedema are here reviewed, focusing on chronic idiopathic urticaria.
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PMID:[Urticaria and angioedema]. 1273 24