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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Food allergy (FA) is one of the causes of atopic dermatitis (AD), of acute urticaria, of reactions of the gastrointestinal tract, and of acute systemic anaphylaxis, but its role in asthma appears to be less clear. The prevalence and incidence of subjects with food-induced wheezing have not been well studied. In addition, the number of subjects with proven food-induced wheezing by double-blind, placebo-controlled oral food challenge (DBPCOFC) has been small. At the moment wheezing is considered unusual in food-hypersensitive subjects, and wheezing as the unique symptom of FA is rare. Furthermore, most cases of food-induced asthma have been observed in children. Food allergy may trigger allergic respiratory symptoms through two main routes: ingestion or inhalation. Children with asthma, who are allergic to foods, present some particular features such as AD and a related significantly elevated total serum IgE level. Alternatively, FA may occur in patients who are "high IgE responder" and more prone to become sensitive to many allergens, including foods. Therefore, children with asthma and a history of AD and/or elevated total serum IgE level should be carefully assessed for FA. We have shown that a significant proportion of children with IgE-mediated cow's milk allergy experienced asthma following DBPCOFC with cow's milk.
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PMID:Food allergy and asthma. 754 49

We investigated whether some cases of chronic urticaria of unexplained cause might be related to food allergy which had remained undetected during routine examination. This investigation was undertaken as the consequence of the availability of a new in vitro assay for specific IgE with increased sensitivity. The following three groups of subjects were studied: 1) a control group of 60 nonatopic subjects, 2) 60 patients with allergy to perennial aeroallergens without skin involvement, and 3) 60 patients suffering from chronic urticaria with no evidence of any triggering factor despite careful clinical investigation. Specific IgE against 19 food allergens frequently involved in urticaria were investigated in all subjects with the new CAP System (Pharmacia). Positive results (CAP > 0.70 kU/l) for one or more food allergens were found in none of the nonatopic controls, in six of the subjects with respiratory allergy, and in 16 of the urticaria patients. The use of an in vitro test with an increased sensitivity allowed us to detect a significant prevalence of IgE specific for food allergens in patients with chronic urticaria of unknown origin. This suggests that, in several of those patients, chronic urticaria might be triggered by a food allergy undetected by the usual methods.
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PMID:Prevalence of IgE antibodies specific for food allergens in patients with chronic urticaria of unexplained etiology. 765 41

Ingested food antigens rapidly cross the gastrointestinal barrier and reach pro-inflammatory cells in the skin. Food allergy provokes urticaria/angioedema by classical, Type I, IgE-mediated hypersensitivity. Food-induced atopic dermatitis is the result of non-classical, IgE-directed hypersensitivity involving resident mast cells, Langerhans cells, CD4+, TH2 lymphocytes and monocytes. A form of gluten sensitivity provokes a characteristic eczematous-like rash and enteropathy (Dermatitis herpetiformis).
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PMID:Mechanisms in adverse reactions to food. The skin. 774 Dec 2

The AIDS progress in the world has led to a considerable increase in the request of medical gloves but also of condoms. At the same time latex hypersensitivity has a growing effect upon our allergology consultations; although the contact dermatitis and urticaria to condoms are frequent, asthma remains very rare. We report one case of condom nocturnal asthma in a patient also presenting a food allergy to sunflower with cross-reactivity to umbelliferae. The different steps of a latex allergy diagnosis are criticized, the populations at risk are mentioned. Nowadays, no standardized allergen exist, therefore we must put the stress on the prevention. Latex hypersensitivity raises an emergency public health issue.
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PMID:[Asthma by proxy (to latex of a condom). General review based on an observation]. 798 38

Food allergy gathers the bulk of pathologies linked to the immuno-allergic response to various foods. It is most often due to an IgE-dependent mechanism. Food allergy may be expressed by various clinical pictures: atopic dermatitis, asthma, anaphylactic shock, urticaria. Its actual incidence is probably underestimated. Diagnosis rests on logical and rigorous advance of thought based on history, physical examination and dietary inquiries. Skin prick-tests constitute the choice method for searching sensitization towards food allergens. Biological assays directed towards specific IgE are second-intention tests. Oral provocation tests constitute the gold standard for establishing the role of a food in the appearance of symptoms. They should be conducted under close medical supervision. Eviction-reintroduction methods represent a heavy diagnostic approach, with rare indications at the present time. The strictness of the methodology used by the allergologist is essential for establishing the diagnosis of food allergy.
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PMID:[Food allergies]. 802 75

Serum samples from 274 patients allergic to one or more of three pollens (birch, grass, mugwort), from 36 patients allergic to cat and/or Dermatophagoides pteronyssinus but not to pollen and from 55 non-allergic controls, as well as 20 cord blood samples, were examined for specific IgE to six 'pollen-associated' food allergens by using a new sensitive assay (CAP). A questionnaire asking for reactions to food was also sent to all patients. In the pollen group, 111 patients (47%) were positive (> or = 0.71 kU/l) for a food allergen (392 positive tests). Of these, 92 were sensitive to apple, 68 to potato, 64 to carrot, 63 to celery, 61 to peach and 44 to melon. In the non-allergic group, no IgE to any of the food allergens tested was found, whereas in the group allergic to non-pollen allergens, only one individual had such an IgE. The CAP assay was found to be more sensitive than RAST for the allergens studied. A history of clinical reactions (oral symptoms in 67, rhinoconjunctivitis in 65, asthma in 42 and urticaria in 39) to the corresponding food allergen was reported mainly by patients with positive CAP. In conclusion, we found a high prevalence of IgE to some food allergens in patients allergic to pollen and the absence of such antibodies in the control groups. The new in vitro assay, being more sensitive than previous ones, indicated a high prevalence of food specific IgE in pollen allergic patients, which in many cases did not correspond to clinical symptoms of food allergy.
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PMID:IgE to food allergens are highly prevalent in patients allergic to pollens, with and without symptoms of food allergy. 803 23

Shellfish is one of the most frequent causes of food allergy. We studied 48 patients (25 male and 23 female) with a mean age of 24.2 +/- 1.8 with shellfish hypersensitivity. A clinical questionnaire was carried out and prick tests were performed using a series of aeroallergens and a battery of extracts of squid, shrimp, lobster, crab, mussel and clam. Prick tests were also performed using raw and boiled extracts from fresh squid, octopus and limpet. Total and specific IgE to these allergens were determined. The most frequent causes of symptoms were shrimp (33 cases) and squid (24 cases). The most frequently found symptoms were Urticaria/angioedema (39 patients), asthma (18 patients) and rhinitis (14 patients). Clinical association was found between Cephalopoedae and Lamelibranquiae (p < 0.05 for clam and p < 0.01 for mussel), but not among both groups and Crustaceans. Association between history and Prick was statistically significant for Crustaceae and Cephalopoedae (p < 0.01) but not for Lamalibranquiae. Association between history and CAP was not found for shellfish. Significant differences among prick-tests with raw and boiled extracts were not found. These results suggest that prick test yields better results than CAP does it, in shellfish hypersensitivity, that clinical association among shellfish hypersensitivity can occurs within the same and different Phylum reflecting common epitopes and that squid, octopus and limpet extracts contain a large amount of heat-stable allergens.
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PMID:Shellfish hypersensitivity: clinical and immunological characteristics. 805 80

Food allergy (hypersensitivity) is a form of adverse food reaction in which the reaction is caused by an immunological response to a food. The majority of immediate allergic reactions to food are IgE-mediated. Although the true prevalence of food allergy is unknown, it is said to be higher in children than in adults. Data suggest that the prevalence in the general population is about 1%. In children the most common foods eliciting an allergic reaction are cow's milk, eggs, fish, peanuts and soy. In adults celery, fish, nuts, peanuts and shrimp are the major source of food allergy. Usually, food-allergic adults are sensitized to pollen, e.g. in the frame of the celery-carrot-mugwort-spice syndrome. There is some evidence that antigenic similarity exists between pollen and food proteins. Clinical signs and symptoms due to food allergy are cutaneous, respiratory, gastrointestinal reactions such as urticaria, laryngeal edema, asthma or diarrhea. Food anaphylaxis is the most severe generalized and sometimes fatal reaction. History, physical examination, skin tests and laboratory tests (RAST) provide the basic tools for identifying a food allergy. However, the "gold standard" for diagnosing allergic food reactions is the double-blind, placebo-controlled food challenge. The predictive accuracy of positive skin tests is less than 50%, as demonstrated by double-blind, placebo-controlled food challenges. The only proven form of management in food allergy is strict elimination of the offending food. Food-allergic individuals must be provided with an emergency kit containing an oral antihistamine of the second generation and a corticosteroid.(ABSTRACT TRUNCATED AT 250 WORDS)
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PMID:[Food allergy]. 814 11

Food origin seems to have a special place in the etiology of infantile urticaria, as it forms 62% of a series of 51 observations of urticaria in children, greater than drug etiology (22%), physical urticaria (8%) and contact urticaria (8%). Distinction between true and false food allergy, which is important for prognosis and evolution, puts true food allergy (55%) in the lead before false (7%). A reason for this, the atopic concept, was seen in 67% of the food urticarias, corresponding apparently to true food allergy. If in the majority of these cases the pathway of sensitizations was unknown, in very rare observations the sensitization pathway was reported as an inhalation or even a sensitization in utero. Finally, infantile urticaria, more serious because of the vital risks that may be associated with it, deserves a special comment from the etiological viewpoint: observation of urticaria (and shock) to peach in an infant of 4 months, to wheat flour at 5 months and egg at 6 months are a demonstration that between 4 and 6 months intolerance of cows milk proteins is not the only etiology of infantile urticaria. For prognosis, early detection of true food allergy in children gives hope of better results than in adults, with higher chances of regression of the sensitization.
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PMID:[Food urticaria in children. Review of 51 cases]. 826 44

In an open clinical study, 80 children and adolescents of 12 months to 20 years of age suffering from asthma bronchiale were treated for a minimum of 8 weeks with DNCG (acecromol) or ketotifen (Zatofug) or with both drugs. Both under the treatment with DNCG and with ketotifen the overall disease pattern was improved with a large proportion of the patients and the concurrent adjuvant medication with prednisolone and/or aminophyllin could be markedly reduced or in some cases discontinued altogether. Both substances appear to be comparable as far as the therapy result is concerned; however, the range of application of ketotifen is wider due to its additional antihistaminic action and oral administration, e.g. in case of concomitant urticaria or food allergy.
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PMID:[DNCG (acecromol) and ketotifen (Zatofug) in treatment of children with bronchial asthma]. 827 78


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