Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042109 (urticaria)
 6,569 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The treatment of cryptosporidiosis has focused primarily on controlling its main symptom, diarrhea. Cryptosporidiosis is found in 10 to 20 percent of people with AIDS who have diarrhea, and as many as 45 million people are exposed to it every year through municipal water systems. Nitazoxanide (NTZ) is an anthelminthic drug that has been available for several years in developing countries where tapeworm and liver fluke infestations are common, and physicians in Texas sometimes prescribe it because it is readily available in Mexican pharmacies. NTZ has not yet been approved in the United States, although Unimed Pharmaceuticals has submitted a New Drug Application for the drug. Results of several clinical trials are presented. Side effects associated with NTZ are rare, but include decreased liver function, discolored urine, and hives. Drug interaction studies have not been completed. Other treatments are reviewed, and information is provided for drug availability and Unimed's expanded access program.
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PMID:Nitazoxanide for cryptosporidial diarrhea. 1136 64