Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042024 (
incontinence
)
13,409
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Laparoscopic radical prostatectomy is an extremely challenging procedure for even experienced laparoscopic surgeons, and it is not practical to expect most urologists to learn the technique. Nevertheless, it is a feasible procedure and has short-term results comparable with conventional radical prostatectomy. For LRP to be an acceptable and reasonable alternative, the oncologic results must be equivalent to the results of
RRP
, and significant advantages is morbidity (hospital stay, pain,
incontinence
, impotence) must be attained; otherwise, the steep learning curve and the additional expense of the procedure make it difficult to justify as an alternative therapeutic modality. Beside a reduction in the transfusion rate, no other significant advantages of LRP over radical prostatectomy have been demonstrated definitively to date. As a result, the role of LRP in the management of prostate cancer remains investigational, and patients should be informed appropriately. The oncologic results and low morbidity of nerve-sparing
RRP
set a high standard for a laparoscopic technique to equal.
...
PMID:Laparoscopic radical prostatectomy: is it feasible and reasonable? 1159 Aug 20
Beginning in the 1980s, a series of anatomical discoveries were introduced to modify the classic retropubic radical prostatectomy proposed by Millin in 1942 in an effort to reduce intra and postoperative complications such as intraoperative bleeding and postoperative erectile dysfunction and
incontinence
.
Urinary incontinence
post retropubic "anatomical" radical prostatectomy remains a distressing problem for the patient and the physician rating from 6 to 20% even in the hands of experienced surgeons from high volume Academic Centers. The reason for the discrepancy in results is unclear and should be searched in surgical experience of the surgeon, volume of surgical activity of the Center, and selection of the patients undergoing the radical retropubic procedure. In the Literature we identified methodological factors which can bias the data on post radical retropubic prostatectomy such as 1) Consensus is lacking on definition of continence and/or
incontinence
following radical retropubic prostatectomy 2) Different surgical techniques are compared: sphincter damaging, versus repairing, versus preserving; bladder neck sparing versus non sparing; nerve sparing versus non sparing 3) Patients with preoperative
urinary incontinence
are included in the series and the preoperative continence status is not known. 4) Different timing in registration of
incontinence
. 5) Different methods in data collection. This latter seems to be the most important reason for discrepancy in the collection of the data. Self administered questionnaires oriented to evaluate
incontinence
analyzed by a third party seem to be the most powerful and objective tool for post prostatectomy
incontinence
rating. Post prostatectomy
incontinence
may be attributed to sphincter dysfunction as a result of surgical injury during prostatic surgery and/or to bladder dysfunction including detrusor instability and decreased compliance resulting in stress or urge or mixed stress/urge postoperative
incontinence
. In the Literature bladder dysfunction is considered to be responsible or jointly responsible for post
RRP
incontinence
in a rate as high as 93%. More recently, a major role is considered to be played in post
RRP
incontinence
pathophysiology by intrinsic sphincter insufficiency. Rarely bladder dysfunction is an isolated cause of
incontinence
. Moreover the symptom of stress incontinence accurately predicts the finding of intrinsic sphincter deficiency. The apical dissection and the preservation of the intrinsic sphincter remain the most complex parts of
RRP
and the keys to the maintenance of postoperative urinary continence.
...
PMID:[Epidemiology and physiopathology of urinary incontinence after radical prostatectomy]. 1182 53