Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0042024 (
incontinence
)
13,409
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Antimuscarinic medications have long been the mainstay of drug treatment for overactive bladder. This article describes mirabegron, one of a new class of agents that relaxes the detrusor muscle directly via a
beta3 adrenoceptor
agonist. Mirabegron's efficacy on frequency, urgency, and urge
incontinence
was tested in several trials before its wide clinical introduction. However, caution is still needed as data are lacking on the drug's efficacy and safety in frail older adults and for long-term therapy.
...
PMID:Mirabegron: A new option in treating overactive bladder. 2650 73
