Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0042024 (incontinence)
13,409 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Questionnaires concerning ailments were sent postpartum (mean two years) to 62 women with anal sphincter ruptures (ASR), who were compared with a matched control population. The frequency of anal sphincter rupture at the hospital during delivery in the period, 1978-82, was 0.7% (n = 63). Primiparity, instrumental deliveries, abnormal presentation, large babies and oxytocin stimulation were all risk factors. Of 59 women answering the questionnaire 37 (63%) stated that they had had ailments three months postpartum, mainly with pain and involuntary passage of flatus but also with dyspareunia and occasional incontinence of faeces. Long-term symptoms were noted by 28 (48%) of the women, mainly with involuntary passage of flatus but also perineal pain, dyspareunia and occasional incontinence of faeces. Long-term symptoms occurred in 7 (88%) of women with ASR also involving the anal mucosa, but only in 21 (39%) of those with ASR only. Three of the patients subsequently underwent reconstructive surgery, and three complained of psychological problems.
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PMID:Long-term ailments due to anal sphincter rupture caused by delivery--a hidden problem. 333 6

Three hundred fifty patients who underwent open or closed lateral internal anal sphincterotomy for acute or chronic anal fissure between January 1981 and June 1985 were reviewed. Minimum follow-up was 14 months (mean, 37 months). No patient underwent an additional procedure at the time of sphincterotomy. Twenty-one failed to heal or developed a recurrence in the interval (6 percent). Five of these individuals were found subsequently to have Crohn's disease. Excluding these patients, the incidence of nonhealing was 4.6 percent. Eight patients (2.3 percent) developed postoperative infections requiring drainage, one half of which were associated with fistulas. Sixty patients (17 percent) complained of incontinence for flatus or feces. For two thirds, this was transient. There was no statistically significant difference in rate of healing or morbidity when comparing the open with the closed method.
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PMID:Long-term results of open and closed sphincterotomy for anal fissure. 336 36

A series of 32 patients operated on for rectal carcinoma is reported. A new technique by using the gracilis muscles to reconstruct a functional anal sphincter after abdominoperineal resection was performed. No operative mortality was recorded. Functionality of the new sphincter was guaranteed by electromyostimulation. Electrostimulation has been useful in both increasing the muscular trophic level and in improving the postoperative bio-feedback. Perineal infection was recorded in 9 patients being the most common complication although it did not compromise the functionality of the new sphincter. In one case acute colonic ischaemia was treated by resection and definitive left colostomy. 17 out of the 27 patients in which a functional follow-up was obtained, scored a "very good" continence to stool and flatus while in 6 patients occasional episodes of incontinence to liquid stool are referred. Local or distant metastases presented in 6 patients. The obtained results encourage in continuing the research with this technique in the attempt to reduce the number of patients that must pay the high price of a definitive abdominal colostomy for cure.
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PMID:Construction of a continent perineal colostomy by using electrostimulated gracilis muscles after abdominoperineal resection: personal technique and experience with 32 cases. 344 42

In a randomized trial we compared the treatment of perianal abscess by incision only (18 patients) with that by incision followed by fistulotomy 3 days later (20 patients). All patients were observed for 12 months. There were no differences between the two groups with regard to recurrent abscess/fistula, but the fistulotomy group had a statistically significantly higher prevalence of flatus incontinence. Further, fistulotomy was followed by significantly longer duration of hospitalization and by delayed healing. We recommend that fistulotomy is used only in patients with recurrent abscess.
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PMID:A randomized trial of fistulotomy in perianal abscess. 355 92

The aim of this study was to evaluate the results of anal surgery performed in 105 patients for perianal symptomatic complications of Crohn's disease. The patients were divided into 3 groups: group I: 45 patients with simple fistulae; group II: 53 patients with complex fistulae; group III: 7 patients with other symptomatic perianal lesions. All patients underwent a resection of their perianal lesions. Complete wound healing was obtained in 95 patients after a mean interval of 11 weeks. Satisfactory results persisted during a mean follow-up of 5 years. The functional results were clinically evaluated in 100 patients: 90 patients were asymptomatic, 6 patients complained of soiling and 4 patients noticed occasional incontinence for flatus and liquid stools. Anorectal function was studied by manometry in the last 31 patients who underwent surgery. Before surgery, the resting anal pressure and the maximal voluntary squeezing pressure were significantly lower than in control subjects. After surgery, there was no statistical difference between the pre- and postoperative results for both parameters. In conclusion, anal surgery in Crohn's disease is hazardous because of the complexity of lesions and preoperative anorectal dysfunction. However, the clinical and functional results obtained in our patients were satisfactory.
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PMID:[Anal surgery in Crohn's disease. Clinical and functional results]. 373 31

To evaluate the application of Parks' classification in the management of patients with fistula-in-ano, a study was undertaken to assess the outcome of surgery, especially with respect to the recurrence rate and alteration of continence. A retrospective analysis of 160 consecutive patients who were classified at the time of operation was conducted. The distribution of fistulas was as follows: intersphincteric, 41.9 percent, transsphincteric, 52.1 percent, suprasphincteric, 1.3 percent, extrasphincteric, 0. A horseshoe extension occurred in 8.8 percent of the fistulas and 3.8 percent did not exactly conform to the classification as they were either complex or combinations of more than one type of fistula. The sole immediate postoperative complication was bleeding, which occurred one week postoperatively and ceased spontaneously (0.7 percent). Alteration in continence occurred in 6 percent of patients with 2.6 percent experiencing temporary incontinence to flatus, 1.3 percent to liquid stool, and 0.7 percent to solid stool. Permanent loss of control for flatus occurred in one patient (0.7 percent) and for liquid stool in one patient (0.7 percent). No patients suffered loss of control for solid stool. Recurrence developed in 6.3 percent of patients, all between five and 25 months postoperatively. Classification was found to be a useful guide in the operative management of patients with fistula-in-ano.
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PMID:Results of treatment of fistula-in-ano. 397 23

Nine women with severe chronic constipation who were unable to expel a water-filled rectal balloon underwent posterior division of the puborectalis muscle. Pre-operative concentric needle electromyography and measurement of the anorectal angle at rest and during straining suggested that the puborectalis muscle failed to relax during attempted defaecation in these patients. Two patients reported improvement after surgery and had normal balloon expulsion after operation. However seven patients reported no benefit from surgery and tests of defaecatory function and anorectal angle did not change. Incontinence for solid stool was not reported following puborectalis muscle division although five patients reported incontinence of flatus, liquid stool and mucus.
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PMID:Experience of posterior division of the puborectalis muscle in the management of chronic constipation. 401 17

This study reviewed 20 cases of extensive squamous carcinoma in situ of the vulva and posterior perineum. Two patients had concurrent, overt invasive carcinoma of the vulva, 14 patients had concurrent extensive vulvar carcinoma in situ, three patients had previous skinning vulvectomy for carcinoma in situ, and one patient had prior treatment for invasive vulvar cancer. Six patients had microinvasive carcinoma in the perianal region, which was unsuspected in five of the women. Nineteen of the 20 patients had involvement of the anal canal, and eight patients had disease extending to, or above, the pectinate line. Nineteen patients were managed by regional resection of the involved perianal/anal skin and mucosa with split thickness skin graft. Routine resection of the anal mucosa to the pectinate line was performed, with margin checks when there was dysplasia in the anal canal. The only noteworthy, long-term adverse effect of resecting the anal mucosa and replacing it with a split thickness skin graft was occasional incontinence of flatus in three of the 19 patients. The skinning procedure with split thickness skin graft produced excellent functional and cosmetic results.
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PMID:Anal involvement by carcinoma in situ of the perineum in women. 646 70

95% of our patients have a simple fistula in ano. The majority of these fistulas were following a cryptoglandular abscess. No definitive incontinence occurred after laying open the fistula penetrating the anal sphincter and excision of the extrasphincteric part. In only 7% there was a temporary incontinence for faeces or flatus respectively. The recurrence rate was 5%. High fistulas are seldom an indication for a seaton. In 5% we found a complex fistula with supralevator or extrasphincteric extension. Thereby we usually performed a defunctioning colostomy. This became the permanent treatment for more than half of these patients.
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PMID:[Treatment of anorectal fistulas: a still current problem]. 651 77

One hundred and seventeen patients with chronic anal fissure were submitted to subcutaneous internal lateral sphincterotomy. Immediate pain relief was observed in all patients except two, in whom sphincterotomy was incomplete. One hundred and ten patients had their first painless bowel movement 24 to 48 hours after the operation. Temporary incontinence to flatus was reported by 38 patients, whereas fecal incontinence was never observed. Healing time of the wound was six days, that of the fissure four weeks. In the 98 patients followed at six months and one year, no complications or recurrences were reported. If particular technical precautions are taken, this type of operation presents several advantages over other procedures, namely posterior midline sphincterotomy and anal stretching.
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PMID:Subcutaneous lateral internal sphincterotomy in the treatment of chronic anal fissure. 667 92


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