Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0040822 (
tremor
)
18,428
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Lithium inhibits the synthesis of prostaglandin (PG) EI by blocking the mobilisation of dihomogammalinolenic acid (DGLA). Toxicity due to lithium might re related to reduced PGEI formation. In five patients who developed toxic effects on low doses of lithium, linoleic acid in the forms of the safflower oil was given in an attempt to raise levels of the linoleic acid metabolite, DGLA. In al five patients the safflower oil was effective in remitting the symptoms of neurotoxicity.
Safflower oil
was also effective in a patient with familial
tremor
.
...
PMID:Linoleic acid in the treatment of lithium toxicity and familial tremor. 739 66
