Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040822 (tremor)
 18,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The effect of pressured environment from 1 to 24 ATA (Atmosphere Absolute) on total power spectrum (TP) of physiological tremor, whose value was the sum of power spectra for frequency range in 0.5-50 Hz, was investigated. The main effects obtained were as follows. (1) In the case of 3 ATA, TP during the pressure holding period denoted a similar value as the value in 1 ATA. In the latter half of the period, the TP increased. When the pressured environment is 4 ATA, in which the partial pressure of the nitrogen gas was 3.6 ATA, the TP decreased during the pressure holding period compared with the value in 1 ATA. Nitrogen narcosis was recognized at the partial pressure of 3.6 ATA, thus the effect denoted a decrease of TP. (2) In the cases of 16 and 19 ATA using heliox gas, during the pressure holding period, TP decreased compared with the value in 1 ATA, but in the case of 24 ATA the value increased. The partial pressure of helium gas of 23.6 ATA indicated a high pressure nervous syndrome, therefore, the influence of high pressure on TP was recognized as one of the causes of the increase of TP. (3) The influence of inhibitors of the autonomic nervous system on TP during the pressure holding period of 3 ATA was recognized. After intake of the inhibitor for the parasympathetic nerve (atropine) during the pressure period, TP increased, while for the intake of the inhibitor for the sympathetic nerve (propanol), TP decreased.
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PMID:Influence of hyperbaric environment on physiological tremor. 1185 Oct 12

Tremor is a well-recognized manifestation of the high pressure nervous syndrome (HPNS). As such, its measurement and analysis during deep hyperbaric exposures can be an important index of central nervous system integrity. During the U.S. Navy's experimental chamber dive to a depth equivalent to 1600 fsw (49.5 ATA), objective measures of intentional tremor were obtained at several depths. Six subjects were pressurized in 6 days to 49.5 ATA. After spending 7 days at this pressure, they were decompressed in 19 days to the surface. Measures of intentional tremor were obtained predive and at pressure levels of 13.1, 31.3, 49.5, 40.4, and 31.3 ATA using the Naval Medical Research Institute Mark 3 Mod 1 tremor device. Each subject's microtremor was measured while he produced a force of 50 grams and 500 grams against a finger force transducer. Unlike previous studies of HPNS tremor, special attention was given to amplitude rather than frequency analysis. All subjects displayed a marked increase in tremor that interfered with fine motor performance at depths greater than 1000 fsw. A statistically significant increase in signal frequency was also observed.
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PMID:Intentional tremor on a helium-oxygen chamber dive to 49.5 ATA. 1562 40


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