Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040822 (tremor)
 18,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Many studies cite no more than 80% incidence of hand tremor during withdrawal in known alcoholics, although this symptom is one of the diagnostic signs of addiction. We found that of 48 patients tested, hand tremor increased in 29 Ss after the application of a passive relaxation technique while it decreased in 28. It was found that MMPI data obtained for both groups fitted the inverted U curve in that the most distressed Ss tremored as little as did the least distressed originally, while the tremor increased in the high stress group after relaxation therapy while it decreased in the least stressed group. Implications for alcoholism research and theory were discussed, and the possible superiority of the CES to drug therapy for withdrawal was noted.
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PMID:A curvilinear relationship between alcoholic withdrawal tremor and personality. 37 Jan 54

Most patients with fibromyalgia use complementary and alternative medicine (CAM). Properly designed controlled trials are necessary to assess the effectiveness of these practices. This study was a randomized, double-blind, placebo-controlled, early phase trial. Fifty patients seen at a fibromyalgia outpatient treatment program were randomly assigned to a daily soy or placebo (casein) shake. Outcome measures were scores of the Fibromyalgia Impact Questionnaire (FIQ) and the Center for Epidemiologic Studies Depression Scale (CES-D) at baseline and after 6 weeks of intervention. Analysis was with standard statistics based on the null hypothesis, and separation test for early phase CAM comparative trials. Twenty-eight patients completed the study. Use of standard statistics with intent-to-treat analysis showed that total FIQ scores decreased by 14% in the soy group (P = .02) and by 18% in the placebo group (P < .001). The difference in change in scores between the groups was not significant (P = .16). With the same analysis, CES-D scores decreased in the soy group by 16% (P = .004) and in the placebo group by 15% (P = .05). The change in scores was similar in the groups (P = .83). Results of statistical analysis using the separation test and intent-to-treat analysis revealed no benefit of soy compared with placebo. Shakes that contain soy and shakes that contain casein, when combined with a multidisciplinary fibromyalgia treatment program, provide a decrease in fibromyalgia symptoms. Separation between the effects of soy and casein (control) shakes did not favor the intervention. Therefore, large-sample studies using soy for patients with fibromyalgia are probably not indicated.
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PMID:Dietary soy supplement on fibromyalgia symptoms: a randomized, double-blind, placebo-controlled, early phase trial. 1899 Jul 24

Among the different types of nanoparticles (NPs) proposed for fingermark detection, silicon oxide nanoparticles (SiO2 NPs) are arguably the most promising due to their unique characteristics. In this study, carboxyl-functionalised SiO2 NPs doped with luminescent ruthenium complex-RuBpy-doped CES-SiO2 NPs-were further studied to investigate their effectiveness for latent fingermark detection. A modified version of the functionalised SiO2 NPs with a lower amount of surface functionalisation is proposed for improved fingermark detection effectiveness. A shaking incubator was also incorporated into the fingermark detection process to offer a more viable treatment approach in comparison to the previously published method. The shaking incubator offered a more robust application approach, as well as improved fingermark detection quality. To gain an insight into fingermark detection effectiveness relative to benchmark techniques, the performance of the optimised RuBpy-doped CES-SiO2 NPs was compared to that of a benchmark fingermark detection method-cyanoacrylate fuming (CAF) followed by luminescent dye staining. Relative fingermark detection effectiveness across the two techniques was evaluated via the treatment of 1724 fingermark specimens. It was concluded that, in general, the benchmark method provided superior detection results. It was evident that the SiO2 NPs are less affected by donor variability but are more dependent on substrate types. Such characteristics are encouraging as they could be favourable to practitioners in casework scenarios where the substrate is known but donor variability is obscure prior to fingermark processing. It should be noted that the overall effectiveness of the proposed NP-based technique will need to be improved before it could be considered for operational implementation.
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PMID:Latent fingermark detection using functionalised silicon oxide nanoparticles: Optimisation and comparison with cyanoacrylate fuming. 3277 89