Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040822 (tremor)
 18,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Research has been carried out into the effects of a new vasoactive substance, buflomedil hydrochloride, on two groups of patients suffering from cerebrovascular insufficiency and obliterating arteriopathy at the lower extremities. Ten clinical parameters were assessed in the first group of patients (insomnia, headache, vertigo, tinnitus, asthenia, shaking, changes in reflexes, anorexia, memory disturbances, problems of concentration and character disturbances); in the second group, the muscular flow of the gastrocnemius as measured by the muscular clearance of NaI131 at rest, during standard exercise conditions, during ten minutes following exercise and in the post-ischaemic phase. The results can be considered satisfactory in both groups, especially after prolonged treatment and in the early stage of the disease. Drug tolerance was very good.
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PMID:[Treatment of chronic cerebrovascular insufficiency and chronic obliterating arteriopathy of the lower extremities with buflomedil hydrochloride]. 404 47

Using cyclosporine as an immunosuppressive drug allowed increasing survival of grafts as well as patients. Despite this drug is being safely used for many years, it can cause complications. The most often complications are nefrotoxicity, hepatotoxicity, diabetes mellitus, arterial hypertension and neurotoxicity. The most often manifestation of neurotoxicity are tremor, leucoencephalopathia, headache and even seizures. Among risk factors we can enumerate arterial hypertetension, low cholesterol level, hypomagnesemia and previous cerebrovascular insufficiency.
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PMID:[Neurotoxicity of cyclosporine]. 1720 51