Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0040822 (
tremor
)
18,428
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hereditary spastic paraplegia
(
HSP
) is group of a rare neurodegenerative disorder with both genetically and clinically diverse neurologic features. Indeed, disease progression is varying greatly within the different forms and current treatment modalities are exclusively symptomatic for
HSP
.
Tremor
in
HSP
patients is only mentioned with rare case reports, so treatment option is lack in clinical ground. We reported a case of a
HSP
-15 girl with a previously reported novel mutation of SPG15 complained of a life disturbing
tremor
and topiramate as a drug therapy for
tremor
in our
HSP
patient.
...
PMID:Topiramate-Responsive Tremor in a Novel Pathogenic Variant of SPG15 Patient. 3250 58
