Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0040822 (tremor)
18,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eight beagles were experimentally inoculated intraotally with Malassezia pachydermatis to induce acute otitis externa. Three or 4 days after the inoculation, the animals showed the symptoms of otitis externa. All ear canals were erythematous and the dogs were shaking their heads. A large number of M. pachydermatis was noticed in exudate taken from every ear canal. Clinical signs of otitis externa were reduced after treatment with 0.1 ml (per canal) of 1% pimaricin suspension twice a day for 3 days. The amount of exudate decreased gradually and 12 of the 16 ear swabs examined, thereafter, were found to be negative for M. pachydermatis within 10 days. No side effects were observed in all the treated cases. These results suggested that M. pachydermatis could induce the canine otitis externa, and that pimaricin is effective agent for M. pachydermatis infection in ear canals.
...
PMID:Otitis externa induced with Malassezia pachydermatis in dogs and the efficacy of pimaricin. 139 Nov 68

A new antimicrobial ear cleanser was evaluated for the treatment of bacterial and yeast ear infection in dogs. Forty-five dogs with erythemato-ceruminous or purulent otitis externa were randomly allocated to two treatment groups: reference ear cleanser (Epiotic, Virbac) or test ear cleanser (Epiotic Advanced, Virbac). Ear cleansing was performed twice daily for 2 weeks, and no other treatment was allowed. By week 2, clinical (exudate quantity, erythema, stenosis, excoriation, and odor) and discomfort (pain, ear scratching, and head shaking) scores were significantly decreased (P < .0001 for all) and no microbial overgrowth could be detected in 25 (64.1%) and 32 (68.1%) ears treated with Epiotic and Epiotic Advanced, respectively. The new pH-balanced, propylene glycol-free test ear cleanser, which incorporates microbial adhesin-blocking carbohydrates, proved as effective as the reference acidic formula.
...
PMID:The efficacy of an antiseptic and microbial anti-adhesive ear cleanser in dogs with otitis externa. 1659 80

Since there is a lack of information about the normal appearance or pathological findings of the equine external ear canal (EEEC) and tympanic membrane (TM), we aimed to find a practical way to perform the otoscopic examination in standing, sedated horses. Therefore, we worked with common veterinary video endoscopes, which are normally used for gastroscopy or bronchoscopy. Both ears each of 38 randomly selected, chemically restrained horses were otoscopically examined. 33 of those horses had no history or signs of potentially ear-associated diseases. However, two horses with vestibular disease and three horses with head shaking were included in the otoscopic examinations. We created references of the normal appearance of the EEEC and TM on the basis of the characteristic anatomical landmarks, degree of debris, amount of keratin scales, shape of the intersection between the cartilaginous (CEEC) and osseous (OEEC) portion of the external ear canal, shape of the OEEC, formation of the keratin layer and its integrity, epithelium colour of the OEEC, and complexion of the TM. With this information, we were able to visualise tympanosclerosis in two equine eardrums, as well as low-grade to severe external otitis in three horses. Severe bilateral external otitis combined with temporohyoid osteoarthropathy (THO) was found in one of those horses. A foreign body was found in one OEEC. This study shows that otoscopic examination is a basic, easy to perform and beneficial diagnostic procedure for a complete work-up of ear-related diseases, such as THO, facial nerve paralysis, vestibular disease, head-shaking or head trauma. Plus, regarding animal welfare, well being of horses is highly influenced by noise exposure. Therefore research on equine audiological aspects needs to be promoted. The standardized otoscopic examination provides an important basis for further research on aural diseases.
...
PMID:Endoscopic findings of the external ear canal in a group of clinically normal horses and horses with head shaking or vestibular disease. 2469 53

Ear disease, such as otitis externa, resulting in aggressive head shaking or ear scratching, is the most common cause of the development of aural hematomas in dogs and cats. An underlying immunologic cause has also been proposed to explain cartilage and blood vessel fragility. Numerous options exist for management of aural hematomas, from medical management alone with corticosteroids, to simple hematoma centesis, to surgical intervention. Because this condition is usually secondary to another disease process, regardless of mode of treatment, likelihood of recurrence is low if the underlying condition is managed properly.
...
PMID:Current Treatment Options for Auricular Hematomas. 2701 35