Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040822 (tremor)
 18,428 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Congenital tremor was experimentally induced in pigs. Eight sows of the Comborough breed that had farrowed for the first time were used, having a good body condition and a liveweight of 115 to 120 kg. Other 96 sows of the same breed and body weight were used as controls. The test animals were given metrifonate orally in the prescribed therapeutic and prophylactic doses (50 mg/kg) four times during pregnancy. Both test and control sows were fed a standard mixture No 16 during pregnancy, and were vaccinated against swine fever, leptospirosis, Aujeszky's disease, and erysipelas. Congenital tremor was manifested in 42 out of 78 offsprings. The following conclusions were drawn: 1. The induced congenital tremor was manifested morphologically by varying hypoplasia of the cerebellum. 2. The use of organic phospohrous compounds for therapeutic and prophylactic purposes should be reduced during pregnancy. 3. The induced congenital tremor in pigs clinically and morphologically similar to the spontaneous congenital tremor in these animals described previously by the same authors.
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PMID:[Metrifonate-induced congenital tremor in piglets]. 734 82

We present a 67 year old patient with erythema and swelling of the right arm. Suspected erysipelas and lymphedema are diagnosed at infectious department in the second month of the disease. He was treated with parenteral antibiotics (clindamycin + quinolon). After that, he was hospitalized at rheumatology department as right hand lymphedema, condition after erysipelas, cervicobrachial syndrome and ulnar epicondylitis of right elbow. Lymphatic drainage of right hand was performed, but with no effect. In the seventh month of the disease, the diagnosis of eosinophilic faciitis was established and started treatment with corticosteroids. Besides mentioned, dizziness, tremor, balance disorders, impaired hearing and pain in the cervical and lumbar spine were apeared. The therapy was introduced with levodopa and ropanirol and there is a slight improvement of neurological manifestations of extrapyramidal syndrome. After 18 months of disease the patient has a contracture of his right shoulder, induration and painful movements right forearm, pronounced tremor of the head and hands, balance disorders, neck pain and back pain, difficulty in walking.
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PMID:[Eosinophilic fasciitis associated with Parkinson's syndrome - a case report]. 2400 83