Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040586 (tracheobronchitis)
 449 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

A 3-mo-old female presented with growth retardation, vomiting, reflux esophagitis, recurrent aspiration pneumonias, and was found to have megaesophagus and microgastria. After the failure of conservative therapy a double-lumen jejunal (Hunt-Lawrence) pouch with distal Roux-en-Y anastomosis was anastomosed to the stomach to increase the gastric reservoir. One year later, there has been progressive weight gain, the megaesophagus and gastroesophageal reflux have lessened significantly, pneumonia has not recurred, and the tracheobronchitis and esophagitis have resolved. This suggests that the gastroesophageal reflux and megaesophagus were due to an inadequate reservoir with a secondary gastric overflow as the esophagus dilated to enlarge the reservoir capacity of the upper gastrointestinal tract. Utilization of a jejunal pouch increased the size of the gastric reservoir, allowed resolution of the secondary esophageal changes, and permitted normal growth to proceed.
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PMID:Management of congenital microgastria with a jejunal reservoir pouch. 746 90

A 3-month-old infant with tetralogy of Fallot and absent pulmonary valve developed necrotizing tracheobronchitis following a radical repair. Right ventricular reconstruction using an equine pericardial valved conduit and plication of the main pulmonary arteries relieved compression of the left main bronchus by the dilated pulmonary artery. However, respiratory distress increased when bronchitis developed. Eventually, both main stem bronchi became stenotic secondary to inflammation, and the patient died 154 days following surgery. Necrotizing tracheobronchitis is a potentially lethal complication in patients with tetralogy of Fallot and absent pulmonary valve.
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PMID:[Necrotizing tracheobronchitis following radical repair in tetralogy of Fallot with absent pulmonary valve--a case report]. 805 26