Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040584 (tracheitis)
 384 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Outbreaks of illness and deaths in sheep after the concurrent administration of a cobalt, copper and zinc mineral supplement and laevamisole are described. Clinical illness was characterised by profound dyspnoea and inability to exercise. The consistent postmortem finding was severe, necrotising tracheitis with partial occlusion of the airway. This lesion was reproduced experimentally by intratracheal administration of the mineral supplement dissolved in one particular formulation of laevamisole but not in water or another preparation of laevamisole. Further experiments revealed that combined zinc sulphate and copper sulphate dissolved in the particular formulation of laevamisole would produce the tracheal lesions.
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PMID:Tracheitis in sheep after oral administration of a mineral supplement. 51 37

An outbreak of mycotic tracheitis was observed in 8000 2-month-old, female White Leghorn birds. The birds were showing difficult respiration and there was mortality of 7-8 birds daily in the flock. On post-mortem examination of the affected birds, the trachea was found to be occluded with a white caseous mass. Microscopically hyphae were found invading the tracheal epithelium, cartilage and serosal layer along with infiltration of macrophages and lymphocytes. Aspergillus fumigatus was isolated in pure culture from the trachea. The birds responded to oral copper sulphate treatment. The ubiquitous occurrence of the organism and the conditions of the harvesting season have been found to be responsible for the outbreak of the disease.
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PMID:Outbreak of mycotic tracheitis in domestic fowl. 831 63