Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0040584 (tracheitis)
384 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Eight clinically healthy calves were inoculated intranasally, four with either noncytopathic or four with cytopathic bovine viral diarrhea virus, and were necropsied 5 or 12 days post-inoculation. The most frequent gross lesion associated with noncytopathic or cytopathic viral infection was proximal colonic mural edema. Consistent microscopic findings were acute to subacute tracheitis, mild enterocolitis with edema, petechial hemorrhages of mesenteric lymph nodes with mild follicular lymphocytic depletion, and paracortical lymphocytic hyperplasia. At necropsy, cytopathic virus was recovered from 4/4 calves and noncytopathic virus was isolated from 2/4 calves. Neutralizing antibodies to noncytopathic bovine viral diarrhea virus were detected in the two calves from which noncytopathic virus was not recovered. Immunohistochemical analysis of lymphoid tissues demonstrated a small, randomly distributed population of mononuclear cells that contained bovine viral diarrhea viral antigen in 7/8 calves.
...
PMID:Experimental primary postnatal bovine viral diarrhea viral infections in six-month-old calves. 216 64

Cytomegalovirus (CMV) infection in patients with the acquired immunodeficiency syndrome (AIDS) can present as either disseminated disease, pneumonitis, retinitis, gastroenteritis, neuropathy, or a subclinical infection. We report a patient whose initial manifestation of CMV infection was severe central airways obstruction due to necrotizing tracheitis. At bronchoscopy, the lesion appeared deeply ulcerated, distinctly different from previously described airway lesions in patients with AIDS. Mucosal biopsies showed characteristic intranuclear and intracytoplasmic inclusions and cultures yielded only CMV. The patient responded partially to ganciclovir, steroids, and antibiotics against suspected anaerobic superinfection but died as a result of central nervous system disease believed due to toxoplasmosis or lymphoma. CMV infection of the upper airway should be considered in the patient with AIDS presenting with atypical cough or stridor and ulcerated endobronchial lesions.
...
PMID:Central airway obstruction due to cytomegalovirus-induced necrotizing tracheitis in a patient with AIDS. 217 87

An adenovirus (isolate 1452) associated with inclusion body hepatitis of bobwhite quails (Colinus virginianus) was characterized as a group I, serotype 1 avian adenovirus and was indistinguishable from quail bronchitis virus. Bobwhite quails were inoculated via the intratracheal or intraperitoneal route with 10(6) mean tissue-culture infective dose of isolate 1452 at 1, 3, 6, or 9 weeks of age. Lesions produced by either route of inoculation were similar to those of quail bronchitis and included necrotizing tracheitis, proliferative and necrotizing bronchitis and pneumonia, and multifocal necrotizing hepatitis, necrotizing splenitis with or without hyperplasia of splenic macrophages, and lymphoid necrosis and atrophy of the bursa of Fabricius. Basophilic intranuclear viral inclusions were present in respiratory mucosal epithelium, hepatocytes and occasionally bile duct epithelium, and the mucosal epithelium overlying follicles of the bursa. Results indicate that isolate 1452 is a field isolate of quail bronchitis virus and that inclusion body hepatitis of bobwhite quails is a manifestation of quail bronchitis.
...
PMID:Further characterization of an avian adenovirus associated with inclusion body hepatitis in bobwhite quails. 217 32

An unusual case of mycotic tracheitis in a young chick caused by Aspergillus fumigatus was recorded from Anand, India, during 1987. The pathogen was demonstrated in the tracheal exudate by potassium hydroxide technique and also recovered from the trachea on Sabouraud dextrose agar at 37 degrees C. The characteristic hyphae of Aspergillus spp. were demonstrated in tracheal mucosa in histopathological sections stained by periodic acid Schiff method. Interestingly, the lesions were confined only to the trachea. Environmental investigations established the source of infection in the farm where the litter was highly contaminated with A. fumigatus.
...
PMID:Aspergillus fumigatus as a cause of mycotic tracheitis in a chicken. 219 Dec 21

The exact diagnosis of pharyngitis remains a problem despite the advent of rapid streptococcal screening. An apparent resurgence of rheumatic fever outbreaks makes it more important to attempt to accurately diagnose pharyngitis. Positive identification of streptococci should be followed by treatment with penicillin, or erythromycin in the patient with penicillin allergy. The patient without positive identification of streptococci will need either observation or further evaluation depending on the degree of illness. Classic croup or laryngotracheobronchitis is a clinical entity that can be diagnosed with reasonable confidence. The few patients that require hospitalization can be treated with humidity, racemic epinephrine, corticosteroids, parental and child support, or any combination of these with good results. Continued observation of all patients with croup is necessary to recognize the uncommon complication of bacterial tracheitis when it occurs. Epiglottitis has a varied clinical appearance and management according to age groups. Infants show a mixed clinical picture similar to croup, but with more obstruction. The classic epiglottitis with acute airway obstruction is seen in the 3-8-year-old age group. Adults have a less fulminant form of supraglottitis. Infants and children will need artificial airway management in most cases, whereas many adults can be treated simply with observation.
...
PMID:Pharyngitis, croup, and epiglottitis. 219 14

A bronchofibroscopy study of cases with histologic investigation of the bronchi and pulmonary mucous biopsy of 29 asbestos-textile workers, revealed diffuse bilateral endo-bronchitis (DBE) with concomitant tracheitis at different stages. No correlation was found between the endoscopy pictures and the clinical manifestations of asbestosis and dust bronchitis. The asbestosis diseased patients displayed pulmonary fibrosis++ without granulomatous inflammation in the asbestos dusts zone. In some cases, bronchial epithelium diffuse metaplasia was diagnosed with some dysplasia elements, as well as papillomatosis and malignant tumours in the lungs. Dust bronchitis++ and asbestosis can perform precancerous conditions in the lungs, what should be taken into account in cancer prevention measures for asbestos industry workers.
...
PMID:[Endoscopic and morphological characteristics of the bronchi and lungs in asbestosis and dust-induced bronchitis in asbestos-textile industry workers]. 221 Apr 23

Acute laryngo-tracheitis in infants represents a common cause of respiratory distress with stridor accompanied with hospital admission. The prognosis is usually favorable in light of the available medical and environmental management. We performed a retrospective analysis of 1739 case reports from 1974 to 1989 with special attention being paid to infants admitted three times or more for recurrent acute laryngo-tracheitis. An ENT consultation was requested in 406 infants which resulted with an endoscopy being performed. Narrowing of the airway was noted in 75% of cases. Dynamics of fluids explains why a silent lesion becomes symptomatic as soon as an inflammatory process is also present. As there are pathologies which are life-threatening, we advocate routine endoscopy as a precautionary method of investigation, followed by close reassessments, in all cases of recurrent acute laryngo-tracheitis with dyspnea. Preferably, this procedure should be performed between dyspneic episodes.
...
PMID:[The value of endoscopy in recurrent acute laryngotracheitis in children. Apropos of 406 cases]. 222 16

Bacterial tracheitis, previously referred to as nondiphtheritic laryngitis with marked exudate, was commonly discussed in pediatric textbooks before 1940. It seemed to disappear as a clinical entity after that time, but it has been recorded with increasing frequency in the pediatric literature since 1979. We describe eight new cases and review 110 previously described cases. The clinical course consists of a prodromal upper respiratory illness with stridor, fever, and a variable degree of respiratory distress. Unlike patients with croup, patients with bacterial tracheitis do not respond to aerosolized racemic epinephrine. Most patients require endotracheal intubation; some require tracheostomy. Reported complications include pneumonia, pneumothorax, formation of pseudomembranes, toxic shock syndrome, and cardiopulmonary arrest. Bacterial tracheitis is a secondary bacterial infection following a primary viral respiratory infection. The most common preceding viral infection is parainfluenza. Staphylococcus aureus and Haemophilus influenzae are the predominant causes of bacterial tracheitis. Secondary bacterial infection may occur as a result of tracheal mucosal injury or impairment of normal phagocytic function due to viral infection.
...
PMID:Bacterial tracheitis: report of eight new cases and review. 223 9

Long-term exposure of rabbits to SO2 gas caused the following changes in the respiratory tract system: decreases in the respiratory rate and pO2 blood level; an increase in the viscosity of sputum associated with increases in protein, unsaturated phosphatidylethanolamine and sphingomyelin; subacute rhinitis, tracheitis and multiple bronchopneumonia. Pretreatment with repeated administrations (inhalations) of N-acetylneuraminic acid remarkably prevented these inflammatory changes. The significance of this finding is discussed.
...
PMID:Effect of N-acetylneuraminic acid on respiratory tract secretion and inflammation in the bronchitic rabbit. 224 15

A 64-year-old man with chronic obstructive pulmonary disease presented with pneumococcal pneumonia that progressed to respiratory failure within one week, requiring mechanical ventilation. Despite a low minute ventilation and clear chest roentgenogram, multiple weaning attempts failed. Bronchoscopy revealed significant narrowing of the distal trachea with erythema, edema, and ulceration of the mucosa. Cytology of tracheal washings was consistent with herpes simplex virus, and the patient was successfully extubated following treatment with intravenous acyclovir. Bronchoscopy following acyclovir therapy demonstrated resolution of the inflammation and narrowing. Herpetic tracheitis is a rarely recognized reversible cause of tracheal stenosis, especially in a nonimmunocompromised patient. It should be suspected in patients without an obvious cause of failure to wean from mechanical ventilation, and can be successfully treated with acyclovir.
...
PMID:Tracheal stenosis and failure to wean from mechanical ventilation due to herpetic tracheitis. 224 99


<< Previous 1 2 3 4 5 6 7 8 9 10 Next >>