Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0040425 (tonsillitis)
 1,594 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

From January 1967 to August 1978, 65 patients with cervical abscesses were referred to the ENT Clinic of Turku University Hospital. The origin of these deep neck infections was odontogenic in 19, tonsillitis or tonsillectomy in 14, trauma in seven, salivary glands in five and branchiogenic cysts in five and other known causes in three cases. In 12 cases the origin was unknown. The cervical abscesses of odontogenic origin were located mostly in the submandibular space (11/19). The rest of the deep cervical infections were mostly found in the parapharyngeal space (25/46). Etiological factors and treatment of these severe infections are discussed.
 ...
PMID:Deep neck infections. 12 Mar 37

The etiology of middle ear disease in Nijmegen, The Netherlands was studied on the basis of a data set collected in a prospective epidemiological study on otitis media with effusion (OME) in a cohort of 1439 preschool children. A factor analysis was used to evaluate two hypotheses: (1) that OME, acute otitis media (AOM), common cold and tonsillitis are manifestations of the same pathological entity, and (2) that a group of children can be distinguished who develop these conditions more frequently than average. The results only partly supported these hypotheses. The correlation between OME, AOM, common cold and tonsillitis was lower than expected from a review of the literature. Common cold appeared to be the ubiquitous ENT disease in childhood and, depending on the child's predisposition, could be accompanied by OME, AOM or tonsillitis. The course of middle ear and upper airway disease showed a gradual scale from "healthy" to "ill" with most of the children suffering from these conditions at an average frequency.
 ...
PMID:An epidemiological approach to the etiology of middle ear disease in The Netherlands. 148 34

In order to evaluate effectiveness and safety of tiaprofenic acid (TA), a multicenter study involving outpatients followed by ENT specialists was carried out. Since October 1988, the trials have prospectively enrolled 4231 patients. The demography of the study's population was: 2165 male and 2066 female, mean age 39.6 +/- 15.8 years. The patients were divided into the following groups by pathology: 1281 (30.4%) otitis, 654 (15.5%) rhinosinusitis, 2178 (51.6%) pharyngo-laryngo-tonsillitis, and 112 (2.6%) flue syndrome, 300 mg b.i.d. of TA was orally administered for seven consecutive days. At T0 and T7 parameters ranged from 75-90% for symptoms related to inflammation of the oral tract, 80% for nasal edema and 100% for otalgia. The physician's judgement about the drug's effectiveness was 90.6% excellent or good. Side effects were reported in 409 cases (9.6%) mainly related to the gastrointestinal tract. There were 72 drop-out (1.7%): 38 (0.9%) for drug intolerance. In conclusion, TA showed excellent safety and effectiveness in improving the recovery of ENT's outpatients.
 ...
PMID:[Efficacy and tolerance of tiaprofenic acid in acute inflammatory ORL diseases: a multicenter study of 4231 patients]. 224 31

Tonsillectomy and adenoidectomy are among the most frequently held operations in the ENT field. In our hospital, the number of cases of tonsillectomy has been decreasing recently as compared with 10 to 15 years ago. Especially the number of cases under 10 years old has shown a decrease. It is sometimes difficult to decide the indication for tonsillectomy even for habitual tonsillitis. In this paper, the post operative course of tonsillectomy with habitual tonsillitis was investigated during 1976 to 1986 using a questionnaire. Answers evaluable were obtained from 207 cases. The efficacy of the operation on sore throats, high temperatures and recurrent colds was very high, but a few cases complained that a foreign sensation of the throat had occurred or worsened after operation. The incidence of nasal allergy gradually increased after tonsillectomy, but further studies may be necessary to decide the exact relationship. Laboratory examinations, such as ASLO, CRP, white blood cell counts, immune complex, C3a and C5a, were not particularly helpful in deciding the indication of tonsillectomy for habitual tonsillitis. In general, it is thought that tonsillectomy is very effective for habitual tonsillitis, but we must be more careful in deciding such an indication.
 ...
PMID:Long-term observation of postoperative course of habitual tonsillitis. 322 63

From a number of medically useful lasers, mainly the neodymium YAG and the carbon dioxide laser are employed in otorhinolaryngology. Until now, the neodymium YAG laser has been used only for coagulation of vessels in Osler's disease and for palliative treatment of malignant tracheo-oesophageal disease. However, the deep coagulation necrosis of the adjacent tissues severely restricts its use. The most widely utilised laser in ENT surgery is the carbon dioxide laser. Its main effect of precise cutting with an extremely fine zone of coagulation reduces bleeding after incision considerably. Secondary tissue reactions, delayed healing, decreased fibroblast activity and maybe more prominent subepithelial scarring, limit its use especially in the glottic region. Therefore, minor vocal cord alterations such as vocal nodules, cysts or polyps suitable for excision with scissors, should not be removed by laser. Optional indications are Reinke's oedema, intubation granulomas and contact pachydermas. Clear advantages of laser use are seen in the treatment of juvenile papillomas of the vocal fold and of smaller vocal cord carcinomas or recurrences after irradiation therapy of these. The carbon dioxide laser is superior to all other indications in the removal of large and obstructing laryngeal carcinomas to prevent tracheostomy. Very reliable is its use in the ablation of lingual tonsillar tissue to improve or eliminate symptoms in recurrent lingual tonsillitis. Transoral resection of small malignant lesions in the oral and pharyngeal cavity may be performed in analogy to electric cautery. The advantages of the laser compared to electrical surgery are a smaller postoperative oedema and less pain, as well as good spontaneous epithelialisation of defects.(ABSTRACT TRUNCATED AT 250 WORDS)
 ...
PMID:[Laser surgery in ENT surgery]. 340 25

Fifty-two adult patients affected by infectious otorhinolaryngological diseases were treated rectally with clofoctol, a new chemotherapeutic phenol derivative. The clinical diagnoses included tonsillitis, paranasal sinus infections, nose and nasopharyngeal infections, external ear canal and middle ear infections. Evaluation of the results was based on clinical and bacteriological data; the effectiveness of the drug was also confirmed by statistical reference to a control group consisting of 52 adult patients affected by otorhinolaryngological infections treated only with topical agents or not treated at all. In the patients treated with clofoctol, good therapeutic results were obtained in over 90% of cases. Only four patients showed mild adverse reactions. On the whole, results demonstrated that clofoctol is very valuable for the management of most of the infectious diseases common in ENT practice.
 ...
PMID:Treatment of ear, nose and throat infections with clofoctol. 391 68

Clinical specimens from 243 patients attending the ENT clinics at King Abdul Aziz University Hospital, Riyadh, Saudi Arabia were investigated for the pathogens attributing to otitis media and tonsillitis. In children as well as in adults with otitis media, the main bacterial causative organisms were Staph, aureus and Ps. aeruginosa; Asp. flavus was detected in 1% and 4% of adult and children cases of otitis media. In tonsillitis H. influenzae, Strept. pneumoniae, Staph. aureus, Strept. gr. A were isolated in only 18% of the children and Strept. pneumoniae, Strept. gr A in 16% of adults. A possible involvement of viruses in tonsillitis is indicated.
 ...
PMID:Ear, nose and throat diseases in Saudi Arabia. Microbiology and clinical observations. 401 55

The efficacy of two commercially available throat lozenges (test preparation with lysozyme, papain and bacitracin as active ingredients, comparative preparation with a disinfectant only) has been tested under conditions of a randomized clinical study. Two groups of 50 patients each with the indications pharyngitis and/or tonsillitis, acute or subacute, have been compared under the conditions of an ENT-practice. The efficacy of the test preparation was established by the general amelioration evaluated by physician and patient and the symptoms reddening, swelling and coating of the throat, pain on swallowing and hoarseness, swelling and pain of lymph nodes. It is supposed that this superiority is due to the enzyme lysozyme and papain in the test preparation.
 ...
PMID:[Therapeutic comparison of throat lozenges (author's transl)]. 678 26

We became aware that a range of antibiotics were being used in our unit to treat patients suffering from tonsillitis or peritonsillar abscess (quinsy). There appeared to be no rationale to determine which antibiotics were used, and we felt that we were possibly using expensive antibiotics when cheaper equally effective ones were available. An audit project was therefore devised to establish the current practice in the ENT Unit at the City Hospital at Edinburgh. Following a six-month prospective pilot study, a protocol for the treatment of tonsillar and peritonsillar sepsis was drawn up and subsequent practice and outcome was then audited, thus completing the audit cycle. As a result substantial savings in the cost of prescribed antibiotics have been made without compromising patient care.
 ...
PMID:Audit of the treatment of tonsillar and peritonsillar sepsis in an ear, nose and throat unit. 764 94

The dynamics in schoolchildren's health status varies in time, as the incidence of some chronic diseases decreases and that of the others increases. As a result, the health status of schoolchildren has deteriorated due to a reduction in the number of healthy children and an increase in the number of chronic patients in the past 30 years. Nervous, immune (allergic), and blood diseases have become frequent. Chronic ENT diseases have been encountered more infrequently due to the noticeable reduction in the incidence rates of tonsillitis and otitis. The positive trend is that schoolchildren have no rheumatism, infective allergic myocarditis, chronic pneumonia and diffuse glomerulonephritis and that the prevalence of locomotor disorders, renal and metabolic (obesity) diseases is low. During school time, the health status of children slightly improves due to the lower incidence rates of chronic diseases and the higher proportion of healthy children, but it has remained still worse than it was 30 years ago. The formation of chronic diseases has been found to occur in health group II children, who have morphological and functional changes, in 50% of cases from the first to the sixth forms and in 20% of cases from the seventh to the tenth forms. The present-day children are characterized by a combination of abnormalities and functional disturbances. This all require active and timely prophylactic measures to block chronization at the premorbid stage. Lifestyle (to keep the hygienic school regime, to do exercises and to go in for sports), sociohygienic conditions and genetic factors have profound effects on the health status.
 ...
PMID:[The health status dynamics of schoolchildren and the importance of biomedical factors in its development]. 768 98


1 2 3 4 5 Next >>