Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Pivot Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Target Concepts:
Gene/Protein
Disease
Symptom
Drug
Enzyme
Compound
Query: UMLS:C0040425 (
tonsillitis
)
1,594
document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)
Hereditary angioedema (HAE) is a rare genetic disorder causing a deficiency in
C1 esterase inhibitor
(
C1-INH
) that is manifested through unpredictable oedema. We describe a case of a patient with HAE who had previously been refused surgery for
tonsillitis
due to the potential for oedema, in whom regular monitoring of
C1-INH
levels combined with intensified therapy with danazol, tranexamic acid and
C1-INH
concentrate enabled an uncomplicated procedure with no oedema crisis. However, clinicians should be alerted that higher overall dosages of
C1-INH
concentrate for perioperative prophylaxis may be required than those typically used to treat acute HAE attacks.
...
PMID:Successful management of hereditary angioedema during tonsillectomy: a case report. 2219 15
