Gene/Protein Disease Symptom Drug Enzyme Compound
Pivot Concepts:   Target Concepts:
Query: UMLS:C0040425 (tonsillitis)
 1,594 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Radioimmunoassay measured serum levels of hydrocortisone in children with chronic decompensated tonsillitis (CDT) before and 7 days, 2-3 months, 3-5 years after tonsillectomy. Hydrocortisone in CDT patients tended to decrease irrespective of decompensation form. The hormone levels were higher in long-term, recurrent course and small mass of the removed tonsils. On posttonsillectomy day 7 hydrocortisone lowered in patients with metotonsillar complications (MTC), remained unchanged in quinsy recurrence and rose in protracted CDT. 2-3 months after the operation adrenal cortex of the majority of patients enhanced its hydrocortisone-producing function. Hydrocortisonemia returned to normal 3-5 years after tonsillectomy, though in MTC its mean values stood higher than in quinsy recurrence.
 ...
PMID:[Cortisol levels in the sera of children with chronic decompensated tonsillitis in different periods after tonsillectomy]. 1059 99

This investigation examined the impact of a multistressor situation on salivary immunoglobulin A (sIgA) levels, and incidence of upper respiratory tract infection (URTI) during the French commando training (3 weeks of training followed by a 5-day combat course). For the URTI, the types of symptoms were classified according to the anatomical location of the infection. Saliva samples were collected (8 a.m.) from 21 males [21 (2) years] before entry into the commando training, the morning following the 3 weeks of training, after the 5-day combat course, and after 1 week of recovery. sIgA, protein and cortisol concentrations were measured. Symptoms of URTI were recorded during the study from health logs and medical examinations. After the 3 weeks of training, the sIgA concentration was not changed, although it was reduced after the 5-day course [from 120 (14) mg l(-1) to 71 (9) mg l(-1), P<0.01]. It returned to pre-training levels within a week of recovery. The incidence of URTI increased during the trial (chi(2)=53.48; P<0.01), but was not related to sIgA. Among the 30 episodes of URTI reported, there were 12 rhino-pharyngitis, 6 bronchitis, 5 tonsillitis, 4 sinusitis and 3 otitis. Cortisol levels were raised after the 3-week training (P<0.01), dropping below baseline after the combat course (P<0.01). Stressful situations have an adverse effect on mucosal immunity and incidence of URTI. However, the relationship between sIgA and illness remained unclear. The large proportion of rhino-pharyngitis indicated that the nasopharyngeal cavity is at a higher risk of infection.
 ...
PMID:Intense training: mucosal immunity and incidence of respiratory infections. 1549 Feb 19