Gene/Protein Disease Symptom Drug Enzyme Compound
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Query: UMLS:C0040425 (tonsillitis)
 1,594 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

The present study is a comparison of malonaldialdehyde (MDA) level and superoxide dismutase (SOD) activity between controls and in tonsillitis patients of different degree before (pre) and after (post) surgery (tonsillectomy). The SOD activity increases in pretonsillectomy cases according to severity of disease and there is a rise in MDA level whereas after tonsillectomy although the increase in SOD is marginal but MDA declines sharply as compared to pretonsillectomy patients indicating that the SOD exerts its protective effect after surgery.
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PMID:A study of free radicals and scavenging enzyme in tonsillitis. 906 74

Superoxide radicals generated in the palatal tonsils by recurrent local infections cause an organic response consistent in synthesis of superoxide dismutase. Tonsillar concentrations of this enzyme correlate with the incidence of tonsillitis. Moreover, superoxide dismutase levels in erythrocytes rise in children proportional to tonsillar concentration in a statistically significant way (y = 0.2356x - 64.918; R2 = 0.9266). The similarities in local and systemic changes in recurrent tonsillitis suggest that the determination of superoxide dismutase in peripheral blood could be a good screening method for determining who should undergo tonsillectomy.
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PMID:[The measurement of superoxide dismutase levels in recurrent tonsillitis. Its practical use]. 1050 8