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Query: UMLS:C0040425 (tonsillitis)
 1,594 document(s) hit in 31,850,051 MEDLINE articles (0.00 seconds)

Species composition and the potency of a microbial focus of the microorganisms on the surface and in the lacunae of the palatine tonsils were studied in 51 patients suffering from chronic tonsillitis and in 52 healthy indivisuals. The species composition of the microorganisms was identical in the groups under study. However, its quantitative indices displayed significant differences. The potency of the microbial focus of the beta-hemolytic streptococci in the tonsillar lacunae of healthy individuals averaged 0.010 +/- 0.02 million, in patients with simple chronic tonsillitis-0.16 +/- 0.05, and in toxicoallergic tonsillitis of the I degree-1.03 +/- 0.8 million microbial cells. The constancy and a marked increase of all the species of microorganisms in the tonsillar lacunae of patients suffering from chronic tonsillitis, and also a marked dependence of this phenomenon on the extent of decompensation of the pathological process led to the conclusion that all of them played a definite role in the pathogenesis of this disease. It is supposed that the pathogenic influence of the mentioned microbes on human organism was realized both on account of summation of the antigenic-allergic and the infectious action, and by its other possible mechanisms.
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PMID:[Role of the microbial flora of the palatine tonsils in the pathogenesis of chronic tonsillitis]. 33 75

The ability of normal canine tonsil cells, and that of humans with chronic tonsillitis, to lyse heteroerythrocytes in vitro is shown. Heterologous erythrocyte destruction by tonsil cells is markedly increased after immunization of the animal. Tonsil cells of patients with chronic tonsillitis lyse the erythrocytes coated with streptococcus and staphylococcus antigens more actively. An experimental tonsillitis increases the ability of tonsils to lyse erythrocytes. Since cytolytic activity of tonsil cells is not altered by the removal of phagocytes and treatment with antiglobulin serum, one can presume that it is caused by T-lymphocytes.
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PMID:Cytolytic activity of tonsil cells. 62 51

The authors studied imprints of tonsillar sections stained both by the method of Pappeneheim and that of Stockinger and Kellner taken from 205 patients with chronic non-complicated tonsillitis, chronic tonsillitis with tonsillocardiac syndrome and chronic tonsillitis with rheumatism, the rheumatic process being of various stages of activity. A comparison of the preparations received shows that the organism's immunologic reformation resulting from the rheumatic process is characterised by growing reticulolymphoblastic, plasmocellular and macrophage reactions and vivification of sinuslymphocytopoiesis which proved to be in strict correlation with the extent of rheumatic activity.
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PMID:[Cellular composition of palatine tonsil imprints in the differential diagnosis of uncomplicated chronic tonsillitis with a tonsillo-cardiac syndrome and chronic tonsillitis with rheumatism]. 98 17

The results are discussed of a retrospective study of 126 patients by whom an excess of the fusospirochaetal complex was found by direct microscopic examination of tonsillar material. These bacteria are not only found in unilateral ulcero-necrotic tonsillitis, but also in different other tonsillar and general diseases. Vincent's angina appears almost exclusively in young persons, aged from 16 to 25 years; in the adolescence (16-20 years) it forms about 40% of all cases of acute tonsillitis. The fusospirochaetal complex is also often found in chronic tonsillitis and even in morfologically normal tonsils, especially in patients with general diseases like rheumatic arthritis. In one third of the patients with infectious mononucleosis, the complex is present in the tonsillar lesions. The occurrence of Vincent's angina is double as high in women than in men. From our assessments we can conclude that the fusospirochaetal complex has a very low pathogenity, and that it only can grow in patients with a reduced local or general resistance, even without causing local lesions.
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PMID:[Significance of the fusospirillum complex (Plaut-Vincent angina)]. 101 88

The authors investigated 46 patients with chronic tonsillitis. Only in 5 (11% blockage in the craniocervical junction were absent. The most frequently affected segment was between the occipital bone and the atlas (in 36 patients), between the atlas and axis in two and between the axis and C3 in three patients. In 28 treatment was only surgical. There blockage disappeared only in four, in two blockage developed operation. Five patients were treated before operation also by manipulation. There the blockage relapsed only once. In 10 treatment was by manipulation only. During the observation period (from 3-9 months) not a single relapse of blockage or tonsillitis was observed during the winter period.
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PMID:[Chronic tonsillitis and the upper cervical spine (author's transl)]. 111 Oct 58

Toxoplasma gondii is known to have an affinity to lymphatic tissue. A series of 506 children with chronic tonsillitis were examined serologically for toxoplasmosis by means of CBR, IIR and ELISA. In 7.7% of the children examined low toxoplasma antibody titers were recorded. Isolation experiments performed on tonsillar tissue of the children with the highest toxoplasma antibody titers were negative. Direct microscopic evidence of tissue toxoplasma cysts failed to be established and the cytopathologic picture characteristic of nodal toxoplasmosis was not present in smears of cells aspirated from lymphatic nodes regional to palatine tonsils. The authors assumed that chronic toxoplasma tonsillitis did not occur in the series studied. In our ecological conditions, T. gondii may not be involved in the etiology of chronic tonsillitis, or it may participate to an extent which is epidemiologically negligible. (Tab. 4, Ref. 14).
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PMID:[The role of Toxoplasma gondii in the etiology of chronic tonsillitis in children]. 152 78

Toxoplasma gondii is know to have an affinity to lymphatic tissue. The authors studied whether after infection of the child's body T. gondii does or does not determine the chronic course of tonsillitis. In 712 children with chronic tonsillitis serological examinations for toxoplasmosis were carried out by means of RVK, NIR and ELISA. Low titers of toxoplasme antibodies were found in 8.0% of the children examined. In light of the following findings the authors conclude that toxoplasme tonsillitis did not occur in their series: toxoplasma antibodies failed to be increased; their titers in seropositive children were low; toxoplasma was not isolated from tonsillar tissue; no direct microscopic evidence of the parasite could be established in smears of cell aspirate from lymph nodes regional to the palatine tonsils; the same smears failed to present the cytopathologic picture characteristic of nodal toxoplasmosis. In our ecologic conditions T. gondii is presumably not involved in the etiology of chronic tonsillitis, or it may be involved but to an epidemiologically not appreciable extent. (Tab. 10, Ref. 18).
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PMID:[The role of Toxoplasma gondii in the etiology of chronic tonsillitis in children]. 180 71

Clinical and immunological examinations of 360 patients with chronic tonsillitis and 286 patients suffering from systemic complications of chronic tonsillitis at various post-tonsillectomy stages demonstrated that the major immunopathological factor in the case of chronic compensated tonsillitis was microbial allergy and in the case of chronic decompensated tonsillitis, autoimmune disorders. The high titer of autoantibodies to tonsillar antigen that persisted at various post-tonsillectomy stages made it necessary to use systemic immune correction as part of therapy of chronic tonsillitis.
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PMID:[The cause-effect interdependence in the pathogenesis of chronic tonsillitis as an infectious allergic process]. 236 Mar 10

The purpose of this study was to clarify the relationship between bacterial flora in tonsillar lacunae and antistreptococcal antibody in sera of the patients with pustulosis palmaris et plantaris (PPP). Since the pustules develops or worsens after tonsillitis in many patients with PPP, a pathogenic role of tonsillar bacteria is suggested, but no significant association has been proven so far. In this study, the aerobes in the tonsillar lacunae were identified and quantitated in 15 adult patients with PPP and 9 adult patients with chronic tonsillitis (CT). In addition, serum streptococcal antigen-specific antibody levels in 40 adult patients with PPP, 18 adult patients with chronic tonsillitis, and 11 healthy volunteers (controls) were examined by enzyme-linked immunosorbent assay (ELISA). The results were as follows. 1. A total of 53 strains (17 species) of aerobes were isolated and identified from the tonsillar lacunae in patients with PPP, while 35 strains (12 species) of aerobes were found in the patients with CT. 2. S. salivarius and S. pneumoniae were the dominant aerobes isolated from patients with PPP or CT. 3. Although the rates of isolation for Staphylococcus and S. pneumoniae were lower in PPP patients than in CT patients, the rate for S. sanguis I was higher in PPP patients than in CT patients. 4. The percentage of alpha, gamma-streptococci to total aerobes in PPP patients was higher than in CT patients. 5. The IgG antibody titers against S. sanguis and S. mitis, and the IgM antibody titers against all streptococci investigated in PPP patients were higher than those in both CT patients and controls. 6. Moreover, both the IgG antibody titers against S. pyogenes T4 and S. sanguis I and the IgM antibody titers against S. sanguis I and S. sanguis II of the patients in which PPP markedly improved after tonsillectomy were higher than those in which PPP showed less improvement postoperatively.
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PMID:[Investigation of the bacterial flora in the tonsillar lacunae and serum levels of streptococcal antigen-specific antibodies in patients with pustulosis palmaris et plantaris]. 238 34

The distribution and proportion of immunoglobulin-producing cells in palatine tonsil, including IgG and IgA subclasses, have been examined in chronic tonsillitis using an immunofluorescence method. Results obtained indicate that the percentage ratios of IgG1:IgG2:IgG3:IgG4 were 53.1:35.9:4.7:6.3. Higher percentages of IgG1- and lower percentages of IgG2-producing cells were found among 3 types of tonsillitis. Proportional ratios of IgA1:IgA2 were approximately 80:20, and a slight elevation of IgA2-producing cells was observed in chronic tonsillitis.
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PMID:Immunoglobulin subclasses in chronic tonsillitis. 247 Aug 82


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